47 research outputs found

    Hyperfine interaction limits polarization entanglement of photons from semiconductor quantum dots

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    Excitons in quantum dots are excellent sources of polarization-entangled photon pairs, but a quantitative understanding of their interaction with the nuclear spin bath is still missing. Here we investigate the role of hyperfine energy shifts using experimentally accessible parameters and derive an upper limit to the achievable entanglement fidelity. Our results are consistent with all available literature, indicate that spin noise is often the dominant process limiting the entanglement in InGaAs quantum dots, and suggest routes to alleviate its effect

    Urinary CD4 T cells identify SLE patients with proliferative lupus nephritis and can be used to monitor treatment response

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    OBJECTIVES: Proliferative lupus nephritis (LN) is one of the major concerns in the treatment of systemic lupus erythematosus (SLE). Here we evaluate urinary CD4 T cells as a biomarker of active LN and indicator of treatment response. METHODS: Urinary CD3CD4 T cells were quantified using flow cytometry in 186 urine samples from 147 patients with SLE. Fourteen patients were monitored as follow-up. Thirty-one patients with other nephropathies and 20 healthy volunteers were included as controls. RESULTS: In SLE, urinary CD4 T cell counts >/=800/100 ml were observed exclusively in patients with active LN. Receiver operator characteristic analysis documented clear separation of SLE patients with active and non-active LN (area under the curve 0.9969). All patients with up-to-date kidney biopsy results showing proliferative LN had high urinary CD4 T cell numbers. In patients monitored under therapy, normalisation of urinary CD4 T cell counts indicated lower disease activity and better renal function. In contrast, patients with persistence of, or increase in, urinary T cells displayed worse outcomes. CONCLUSIONS: Urinary CD4 T cells are a highly sensitive and specific marker for detecting proliferative LN in patients with SLE. Furthermore, monitoring urinary CD4 T cells may help to identify treatment responders and treatment failure and enable patient-tailored therapy in the future

    Electronic stopping of slow protons in oxides: Scaling properties

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    Electronic stopping of slow protons in ZnO, VO2 (metal and semiconductor phases), HfO2, and Ta2O5 was investigated experimentally. As a comparison of the resulting stopping cross sections (SCS) to data for Al2O3 and SiO2 reveals, electronic stopping of slow protons does not correlate with electronic properties of the specific material such as band gap energies. Instead, the oxygen 2p states are decisive, as corroborated by density functional theory calculations of the electronic densities of states. Hence, at low ion velocities the SCS of an oxide primarily scales with its oxygen density.Financial support of this work by the FWF (FWF-Project No. P22587-N20 and FWF-Project No. P25704-N20) is gratefully acknowledged. M. A. and J. I. J. acknowledge financial support by the Gobierno Vasco-UPV/EHU Project No. IT756-13, and the Spanish Ministerio de Economía y Competitividad (Grants No. FIS2013-48286-C02-02-P and FIS2016-76471-P). Fabrication and characterization of VO2 films at Vanderbilt University (CMG and RFH) was supported by a grant from the National Science Foundation (DMR-1207507). A research infrastructure fellowship of the Swedish Foundation for Strategic Research (SSF) under Contract No. RIF14-0053 supporting accelerator operation is acknowledged.Peer Reviewe
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