1,664 research outputs found
Persistent LHPA Activation in German Individuals Raised in an Overprotective Parental Behavior
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.Parental upbringing may affect their offspring’s mental state across the entire lifespan. Overprotective parental child-rearing style may increase the disease burden in the offspring. Furthermore, this child-rearing style may also play a pathogenetic role by transmitting trauma- and stressor-related disorders (TSRD) across generations. Studies with animals have demonstrated that the mother’s immediate and expansive protection of the newborn decreases the limbic-hypothalamic-pituitary-adrenal (LHPA) axis activity in the offspring. However, few studies have investigated how stress impact humans raised in an overprotective manner. In a cross-sectional study with 40 healthy students recalling their overprotective upbringing, we show an increase in the dehydroepiandrostendione (DHEA) concentration and a reduction in the cortisol/DHEA-ratio in hair. Additionally, this child rearing style was associated with heightened indications of mental burden, depressiveness, and sense of coherence. Our results provide insight into the roots and consequences of psychological trauma across several generations. Further investigations focusing particularly on multigenerational transmission in extremely burdened families will augment our results
The Ni(n,) cross section measured with DANCE
The neutron capture cross section of the s-process branch nucleus Ni
affects the abundances of other nuclei in its region, especially Cu and
Zn. In order to determine the energy dependent neutron capture cross
section in the astrophysical energy region, an experiment at the Los Alamos
National Laboratory has been performed using the calorimetric 4 BaF
array DANCE. The (n,) cross section of Ni has been determined
relative to the well known Au standard with uncertainties below 15%.
Various Ni resonances have been identified based on the Q-value.
Furthermore, the s-process sensitivity of the new values was analyzed with the
new network calculation tool NETZ.Comment: 11 pages, 13 page
Non-Statistical Effects in Neutron Capture
There have been many reports of non-statistical effects in neutron-capture
measurements. However, reports of deviations of reduced-neutron-width
distributions from the expected Porter-Thomas (PT) shape largely have been
ignored. Most of these deviations have been reported for odd-A nuclides.
Because reliable spin (J) assignments have been absent for most resonances for
such nuclides, it is possible that reported deviations from PT might be due to
incorrect J assignments. We recently developed a new method for measuring spins
of neutron resonances by using the DANCE detector at LANSCE. Measurements made
with a 147Sm sample allowed us to determine spins of almost all known
resonances below 1 keV. Furthermore, analysis of these data revealed that the
reduced-neutron-width distribution was in good agreement with PT for resonances
below 350 eV, but in disagreement with PT for resonances between 350 and 700
eV. Our previous (n,alpha) measurements had revealed that the alpha strength
function also changes abruptly at this energy. There currently is no known
explanation for these two non-statistical effects. Recently, we have developed
another new method for determining the spins of neutron resonances. To
implement this technique required a small change (to record pulse-height
information for coincidence events) to a much simpler apparatus: A pair of C6D6
gamma-ray detectors which we have employed for many years to measure
neutron-capture cross sections at ORELA. Measurements with a 95Mo sample
revealed that not only does the method work very well for determining spins,
but it also makes possible parity assignments. Taken together, these new
techniques at LANSCE and ORELA could be very useful for further elucidation of
non-statistical effects.Comment: 8 pages, 3 figures, for proceedings of CGS1
Spin measurements for 147Sm+n resonances: Further evidence for non-statistical effects
We have determined the spins J of resonances in the 147Sm(n,gamma) reaction
by measuring multiplicities of gamma-ray cascades following neutron capture.
Using this technique, we were able to determine J values for all but 14 of the
140 known resonances below En = 1 keV, including 41 firm J assignments for
resonances whose spins previously were either unknown or tentative. These new
spin assignments, together with previously determined resonance parameters,
allowed us to extract separate level spacings and neutron strength functions
for J = 3 and 4 resonances. Furthermore, several statistical test of the data
indicate that very few resonances of either spin have been missed below En =
700eV. Because a non-statistical effect recently was reported near En = 350 eV
from an analysis of 147Sm(n,alpha) data, we divided the data into two regions;
0 < En < 350 eV and 350 < En < 700 eV. Using neutron widths from a previous
measurement and published techniques for correcting for missed resonances and
for testing whether data are consistent with a Porter-Thomas distribution, we
found that the reduced-neutron-width distribution for resonances below 350 eV
is consistent with the expected Porter-Thomas distribution. On the other hand,
we found that reduced-neutron-width data in the 350 < En < 700 eV region are
inconsistent with a Porter-Thomas distribution, but in good agreement with a
chi-squared distribution having two or more degrees of freedom. We discuss
possible explanations for these observed non-statistical effects and their
possible relation to similar effects previously observed in other nuclides.Comment: 40 pages, 13 figures, accepted by Phys. Rev.
Pattern formation and localization in the forced-damped FPU lattice
We study spatial pattern formation and energy localization in the dynamics of
an anharmonic chain with quadratic and quartic intersite potential subject to
an optical, sinusoidally oscillating field and a weak damping. The
zone-boundary mode is stable and locked to the driving field below a critical
forcing that we determine analytically using an approximate model which
describes mode interactions. Above such a forcing, a standing modulated wave
forms for driving frequencies below the band-edge, while a ``multibreather''
state develops at higher frequencies. Of the former, we give an explicit
approximate analytical expression which compares well with numerical data. At
higher forcing space-time chaotic patterns are observed.Comment: submitted to Phys.Rev.
Global Inverse Consistency for Interactive Constraint Satisfaction
International audienceSome applications require the interactive resolution of a constraint problem by a human user. In such cases, it is highly desirable that the person who interactively solves the problem is not given the choice to select values that do not lead to solutions. We call this property global inverse consistency. Existing systems simulate this either by maintaining arc consistency after each assignment performed by the user or by compiling offline the problem as a multi-valued decision diagram. In this paper, we define several questions related to global inverse consistency and analyse their complexity. Despite their theoretical intractability, we propose several algorithms for enforcing global inverse consistency and we show that the best version is efficient enough to be used in an interactive setting on several configuration and design problems. We finally extend our contribution to the inverse consistency of tuples
Integration of airborne and ground observations of nitryl chloride in the Seoul metropolitan area and the implications on regional oxidation capacity during KORUS-AQ 2016
Nitryl chloride (ClNO2) is a radical reservoir species that releases chlorine radicals upon photolysis. An integrated analysis of the impact of ClNO2 on regional photochemistry in the Seoul metropolitan area (SMA) during the Korea-United States Air Quality Study (KORUS-AQ) 2016 field campaign is presented. Comprehensive multiplatform observations were conducted aboard the NASA DC-8 and at two ground sites (Olympic Park, OP; Taehwa Research Forest, TRF), representing an urbanized area and a forested suburban region, respectively. Positive correlations between daytime Cl2 and ClNO2 were observed at both sites, the slope of which was dependent on O3 levels. The possible mechanisms are explored through box model simulations constrained with observations. The overall diurnal variations in ClNO2 at both sites appeared similar but the nighttime variations were systematically different. For about half of the observation days at the OP site the level of ClNO2 increased at sunset but rapidly decreased at around midnight. On the other hand, high levels were observed throughout the night at the TRF site. Significant levels of ClNO2 were observed at both sites for 4-5 h after sunrise. Airborne observations, box model calculations, and back-trajectory analysis consistently show that these high levels of ClNO2 in the morning are likely from vertical or horizontal transport of air masses from the west. Box model results show that chlorine-radical-initiated chemistry can impact the regional photochemistry by elevating net chemical production rates of ozone by 25% in the morning
FishFace: interactive atlas of zebrafish craniofacial development at cellular resolution
Background: The vertebrate craniofacial skeleton may exhibit anatomical complexity and diversity, but its genesis and evolution can be understood through careful dissection of developmental programs at cellular resolution. Resources are lacking that include introductory overviews of skeletal anatomy coupled with descriptions of craniofacial development at cellular resolution. In addition to providing analytical guidelines for other studies, such an atlas would suggest cellular mechanisms underlying development. Description We present the Fish Face Atlas, an online, 3D-interactive atlas of craniofacial development in the zebrafish Danio rerio. Alizarin red-stained skulls scanned by fluorescent optical projection tomography and segmented into individual elements provide a resource for understanding the 3D structure of the zebrafish craniofacial skeleton. These data provide the user an anatomical entry point to confocal images of Alizarin red-stained zebrafish with transgenically-labelled pharyngeal arch ectomesenchyme, chondrocytes, and osteoblasts, which illustrate the appearance, morphogenesis, and growth of the mandibular and hyoid cartilages and bones, as viewed in live, anesthetized zebrafish during embryonic and larval development. Confocal image stacks at high magnification during the same stages provide cellular detail and suggest developmental and evolutionary hypotheses. Conclusion: The FishFace Atlas is a novel learning tool for understanding craniofacial skeletal development, and can serve as a reference for a variety of studies, including comparative and mutational analyses
- …