135 research outputs found

    Internal audit function and application of good corporate governance at public Indonesian commercial banks

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    This study aims to analyze the internal audit function, analyze the application of good corporate governance and analyze the influence of the internal audit function on the implementation of good corporate governance. Deviations that occur in a company can be prevented by the implementation of good corporate governance adequately, and to achieve the application of good corporate governance, a quality internal audit is needed. The method used in this research is descriptive verification method. The sample of this study was 60 respondents, consisting of leaders and audit teams from three government commercial banks. The sampling technique is Nonprobability sampling, namely census sampling by collecting data using questionnaires and interviews. The results showed that the internal audit function was carried out adequately, the implementation of good corporate governance was carried out adequately and the internal audit function had an effect on the implementation of good corporate governance. To maximize the internal audit function in a government commercial bank (SOE’s Bank), internal auditors must be able to provide property protection to the company, and to achieve the principles of good corporate governance in accordance with what has been outlined, employee competency is needed in accordance with the internal.peer-reviewe

    Klon Gen Penisilin Asilase Pada Cosmid Phc79

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    Penicillin acylase plays an important role in the catalysis of benzylpenicillin hydrolytic reaction, prodeucing 6-aminopenicilanic acid (6- APA), a precursorfor the formation of penicillinderivatives. Cloning of the penicillin acylase gene of Escherichia coli B130 chromosomal DNA on pHC79 cosmid vector to increase the enzyme activity has been investigated. The cloning was cooducted with several steps, including isolation of the chromosomal DNA. digestion by restriction enzyme, ligation by T4-DNA ligase, transformation of the recombinant DNA, and selection of the transformans. Microbial assay utilizing Serratia marcescens was carried out for screening the penicillin acylase colony, whereas the determination of the enzyme activity was examined based on Kornfeld method. From 2070 colonies screened by S. marcescens, only 4 positive colonies were obtained. The enzyme activity of these colonies was 4-6 fold higher than the penicillin acylase activity from E. coli B 130

    Studi Efektivitas Kepemimpinan Kepala Sekolah

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    A Study on the Effectiveness of Principal LeadershipThe main aim of the present study is to describe empirical description and to analyze how far the influence of principal leadeship's effectiveness and its impact to the increasing of the school performance from variables. The variabels are personal characteristic, leading behavior, work qualification, and the task context of the principal. The subject and respondents of the present study are teachers from Private Junior High School in Cimahi, West Java. This study uses qualitative approach by applying path analysis to desribe and explain each variable condition in detail and to examine the causality relationship between the variables. The research sample studied is the entire private junior high school in the town of Cimahi, calculated to as much as 24 schools with research respondents as many as 390 people (teachers) from all the private junior high school

    A Multisectoral Approach in Dengue Management in Seremban Malaysia: an Ecobiosocial Perspective

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    Background: Dengue has been established as a major public health issue in many parts of the world particularly those in the tropical regions. In Malaysia, the rising rate of dengue cases had remained uncurbed, alarming to both the public and the local authorities. Despite the existence of legislations and control activities, why does the number of dengue cases keep on increasing every year? The objective of this study was to assess the existing environmental and health policies/strategies towards sustainable prevention and control of dengue/DHF in Malaysia. In addition, it also aimed to review the eco-bio-social approach and its advantages in prevention and control of dengue. Subjects and Method: Series of in-depth interviews were conducted on 12 key- informants aged between 36-58 years old. They were selected based on their roles that were divided into three categories, i.e. (1) policy makers, (2) middle managers, and (3) implementers at the ground level. Each interview explored in detail, on the important domains which were the ecology, biology, and social factors. Each session took an average of 45 minutes to 1 hour. There were a total of 10 males and 2 females selected for the in-depth interview. Open-ended questions were asked and the interviews were voice recorded, after obtaining consent from the respondents. The interviews were terminated once data saturation was achieved. The qualitative data was analyzed using Atlas.ti software. Results: The three main themes that emerged and were identified to contribute to sustainable dengue control and prevention were (1) adequate implementation of existing health policy, (2) good integration and coordination between agencies, (3) commitment from political and community leaders. Local data showed that areas which did not have these important components became hot spots for dengue with high number of dengue cases. Conclusion: It is vital that the community and relevant authorities focus on these themes/domains that will significantly improve the chances of having sustainable denguecontrol and management program in their localities. Keywords: multisectoral approach, ecobiosocial, engue control, sustainable managemen

    Pengembangan Media Pembelajaran Berbasis Android Pada Mata Pelajaran Fisika Menggunakan APPYPIE di SMK Armida Abdulladin Polewali Mandar

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    Penelitian ini bertujuan untuk menghasilkan pengembangan media pembelajaran berbasis androidmenggunakan online builder appypie pada materi Gerak dan Gaya di SMK Armida Abdulladin. Penelitian ini menggunakan metode penelitian dan pengembangan (research and development) menggunakan model Dick and Carey yang terdiri dari tahapan menentukan tujuan pembelajaran, melakukan analisis pembelajaran, mengidentifikasi karakteristik siswa, merumuskan tujuan pembelajaran, mengembangkan instrumen penilaian, mengembangkan strategi pembelajaran, mengembangkan dan memilih bahan pembelajaran, mendesain dan melaksanakan evaluasi formatif, dan merevisi produk pembelajaran. Subjek penelitian ini adalah siswa kelas X jurusan Multimedia SMK Armida Abdulladin. Data penelitian diperoleh dari hasil angket validasi ahli materi, angket validasi ahli media, dan angket tanggapan siswa. Hasil dari tingkat kelayakan berdasarkan penilaian ahli materi, ahli media, dan tanggapan atau respon siswa. Hasil penilaian media pembelajaran berdasarkan penilaian ahli materi mendapatkan nilai 4,48 dengan kategori sangat baik, penilaian ahli media mendapatkan nilai 3,97 dengan kategori baik, serta hasil uji coba media pembelajaran appypie mendapat nilai 89,6% dengan kategori sangat baik, dan respon siswa untuk penggunaan langsung media pembelajaran mendapatkan nilai 91,37 dengan kategori sangat baik dari siswa kelas X jurusan Multimedia SMK Armida Abdulladin. Dari penilaian ahli media, ahli materi, dan tanggapan/respon siswa, media pembelajaran appypie berbasis android pada materi Gerak dan Gaya termasuk dalam katergori layak untuk digunakan. Keywords— Media pembelajaran, Gerak dan Gaya, Android, Appypie

    Pengaruh Peningkatan Lipofilisitas Pada Senyawa Analog Uk-3a Dalam Menghambat Pertumbuhan Sel Kanker P-388

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    Antibiotic UK-3A contains a 9-membered dilactone ring. It had been isolated as a minor component from the mycelium of 5trepyomyces sp. 51701.The antibiotic was hypothesized to be potential to inhibit the growth of leukemia cancer cell line of P388 and KB with ICso 38 and 20 Dg/mL, respectively. To understand the effect of lipophilicity increase of the analogues on their anticancer activities based on QSAR parameter (Log P) and binding energy to BcL-xL protein. To produce analogues of UK-3A, 3hydroxypicolinyl serine methyl ester (A) was synthesized from 3-hydroxypicolinic acid and L-serine methyl ester. The product was then esterified by pentanoic (1), hexanoic (2), heptanoic (3), and octanoic (4). The final products were confirmed with IHand 13C FT-NMR and FTIR spectra, and also MS spectra. Then they were tested against P388 Murine Leukemia cells. The result of bioassay showed lipophilicity increase of3hydroxypicolinyl serine methyl octhyl ester (PSMOE) correlated positively with their anticancer activity increase, withICso 15.4mg/mL against P388 cell lines

    Survei Cepat terhadap Tikus dan Keong Perantara Schistosomiasis di Daerah Endemis, Dataran Tinggi Bada Kabupaten Poso, Sulawesi Tengah

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    Schistosomiasis merupakan penyakit terabaikan (neglected disease) yang ditemukan endemis di Sulawesi Tengah, yaitu di Dataran Tinggi Lindu, Napu dan Bada. Dataran tinggi Bada merupakan daerah endemis schistosomiasis yang baru ditemukan pada tahun 2008. Survei cepat ini bertujuan untuk mendapatkan informasi mengenai infection rate schistosomiasis pada keong Oncomelania hupensis lindoensis dan tikus, serta identifikasi tikus sebagai mamalia hospes definitif selain manusia di Bada. Survei dilakukan pada bulan Januari 2015. Pemeriksaan serkaria keong dilakukan dengan metode crushing. Tikus yangdiperoleh diidentifikasi kemudian dibedah untuk memperoleh cacing chistosoma japonicum dan penentuan infection rate pada tikus. Ditemukan tiga keong positif serkaria S.japonicum (infection rate 15%) dari 20 keong yang diperiksa. Diperoleh tiga ekor tikus positif cacing S.japonicum dari 20 perangkap yang dipasang (infection rate 100%). Jenis tikus yang diperoleh adalah Rattus norvegicus, R.argentiventer dan Paruromys dominator. Hasil survei menunjukkan bahwa tingkat infeksi schistosomiasis pada binatang cukup tinggi, sehingga menyebabkan siklus silvatik terus berlangsung
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