Prediction of emissions and profits from a biomass, tyre, and coal fired co-gasification CHP plant using artificial neural network: Nigerian and South African perspectives

Abstract : The local sourcing of feedstock for energy generation will reduce costs in the power plant, and promote energy sustainability. Most times, potential investors in this area show interest about understanding the profitability of the business because, the information boosts the confidence of the investors in the project, and gives them the opportunity of making a short and long term plans about the business. The emissions arising from the energy plant is an important aspect of the venture that requires proper attention, otherwise the costs of emission control may consume a greater part of the profit, hence rendering the business un-viable. Nigeria and South Africa (SA) have abundant biomass (e.g. corn cob, sugarcane bagasse, & pine saw dust) coal and tyre that can be used as fuel in an energy plant. A 10 MW CHP plant was fired with coal and biomass, and tyre obtained from Nigeria and South Africa (SA) respectively, at ratios of 1:1, 3:2, and 4:1 to study the emissions and profits in the plant. An empirical model was employed to estimate the annual amount of feedstock and feed rate required for the plant, after which, an artificial neural network (ANN); LevenbergMarquardt algorithm was used to predict the emissions and profits in the plant for 20-year- investment period with feedstock costing (WFC) and without feedstock costing (WOFC). The profit obtained from the South African feedstock, WFC and WOFC; produced about 45.18 % and 36.83 % ($3,900,000.07 and$3,179,184.49) higher profits than the Nigerian feedstock, but the CO, NOX, & SO2 emissions from Nigerian feedstock were lower than that of SA. The findings from this study could be used as a platform for decision making by potential investors and stake-holders, and further research and development in the area

Review of prostate cancer research in Nigeria

Prostate cancer (CaP) disparities in the black man calls for concerted research efforts. This review explores the trend and focus of CaP research activities in Nigeria, one of the ancestral nations for black men. It seeks to locate the place of the Nigerian research environment in the global progress on CaP disparities. Literature was reviewed mainly through a Pubmed search with the terms “prostate cancer”and “Nigeria”, as well as from internet and hard copies of journal pages

Prevalence of intestinal parasitic infections among HIV patients in Benin City, Nigeria

This study was carried out to determine the presence of intestinal parasites and their correlation with CD4+ T-cell counts and demographics among human immunodeficiency virus (HIV)-positive patients in Benin City, Nigeria. Stool specimens from 2,000 HIV-positive patients and 500 controls (HIV-negative individuals) were examined for ova, cysts, or parasites, using standard procedures. In addition, patient's blood samples were analyzed for CD4 counts by flow cytometry. An overall prevalence rate of 15.3% was observed among HIV-positive patients while 6.2% was noted among non-HIV subjects. HIV status was a significant (P<0.0001) risk factor for acquiring intestinal parasitic infections. Male gender, CD4 count <200cell/µl, and diarrhea were significantly associated with an increased prevalence of intestinal parasitic infections among HIV-positive patients. The level of education, occupation, and source of water among HIV patients significantly (P<0.0001) affected the prevalence of intestinal parasitic infections. Ascaris lumbricoides was the most predominant parasite in both HIV-positive patients and controls. A CD4 count <200 cells/µl was significantly associated with only Isospora belli and Cryptosporidium infections. The presence of pathogenic intestinal parasites such as A. lumbricoides, hookworm, Giardia intestinalis, Entamoeba histolytica, Trichuris trichiura, and Taenia species among HIV-infected persons should not be neglected. Cryptosporidium species and I. belli were the opportunistic parasites observed in this study. Routine screening for intestinal parasites in HIV-positive patients is advocated

Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer's disease: An international overview

Introduction: The current practice of quantifying cerebrospinal fluid (CSF) biomarkers as an aid in the diagnosis of Alzheimer's disease (AD) varies from center to center. For a same biochemical profile, interpretation and reporting of results may differ, which can lead to misunderstandings and raises questions about the commutability of tests. Methods: We obtained a description of (pre-)analytical protocols and sample reports from 40 centers worldwide. A consensus approach allowed us to propose harmonized comments corresponding to the different CSF biomarker profiles observed in patients. Results: The (pre-)analytical procedures were similar between centers. There was considerable heterogeneity in cutoff definitions and report comments. We therefore identified and selected by consensus the most accurate and informative comments regarding the interpretation of CSF biomarkers in the context of AD diagnosis. Discussion: This is the first time that harmonized reports are proposed across worldwide specialized laboratories involved in the biochemical diagnosis of AD

The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact

\ua9 2024 The Authors. Alzheimer\u27s &amp; Dementia published by Wiley Periodicals LLC on behalf of Alzheimer\u27s Association.Two of every three persons living with dementia reside in low- and middle-income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs occur in high-income countries (HICs), with dementia research predominantly focusing on HICs. This imbalance necessitates LMIC-focused research to ensure that characterization of dementia accurately reflects the involvement and specificities of diverse populations. Development of effective preventive, diagnostic, and therapeutic approaches for dementia in LMICs requires targeted, personalized, and harmonized efforts. Our article represents timely discussions at the 2022 Symposium on Dementia and Brain Aging in LMICs that identified the foremost opportunities to advance dementia research, differential diagnosis, use of neuropsychometric tools, awareness, and treatment options. We highlight key topics discussed at the meeting and provide future recommendations to foster a more equitable landscape for dementia prevention, diagnosis, care, policy, and management in LMICs. Highlights: Two-thirds of persons with dementia live in LMICs, yet research and costs are skewed toward HICs. LMICs expect dementia prevalence to more than double, accompanied by socioeconomic disparities. The 2022 Symposium on Dementia in LMICs addressed advances in research, diagnosis, prevention, and policy. The Nairobi Declaration urges global action to enhance dementia outcomes in LMICs

Production of yeast biomass with elevated content of glutathione

Research on biosynthesis of glutathione (GSH) by yeast Saccharomyces cerevisiae was undertaken with the aim of achieving high content of this compound intracellularly. The effect of GSH-amino-acids free and GSH-amino-acids enriched media added alone or in combination at different concentrations were examined. Furthermore, the combined effect of carbon and sulphur were also investigated. Cultivations were performed in shake-flasks at 28°C for 24-48 h in a synthetic medium with saccharose and ammonium sulphate as the sources of carbon and sulphur. The strain Saccharomyces cerevisiae cultured in GSH-amino-acids enriched media accumulated about 11-20 mg GSH/g d:ry biomass and the content of biomass was 6.5-12.5 g dry biomass/dm3 after 24 h of cultivation. Cysteine added alone to the medium was confirmed as the key amino-acid responsible for the increased biosynthesis of GSH in the yeast cell. In addition, increase in the sulphur content exerted a marked positive effect on its biosynthesis

The relationship between prevalence and severity of lower urinary tract symptoms (LUTS), and body mass index and mid-abdominal circumference in men in a resource-poor community in Southeast Nigeria: a cross-sectional survey

Abstract Background There is paucity of information on the community-based prevalence and severity of lower urinary tract symptoms (LUTS) in men who are 40 years and older in the southeast region of Nigeria. This study seeks to determine the community-based prevalence of LUTS and the relationship between LUTS, and body mass index (BMI) and mid-abdominal circumference (MAC) in men. Methods An interviewer-administered, questionnaire-based survey. Three of nine settlement clusters were randomly selected while systematic random sampling of 1 in 3 eligible subjects was used to select participants. Analysis was done using SPSS® version 20. Results One thousand three hundred and nineteen duly completed questionnaires were analyzed. The respondents are within ages 40-92 years with mean age 54.2 ± 10.2 years, mean BMI 25.97 ± 4.18Kg/m2 and mean MAC 89.80 ± 12.43 cm. Overall prevalence of LUTS is 20.2%. Nocturia at a prevalence of 19.2% is the most prevalent lower urinary tract symptom and also the earliest to manifest. LUTS prevalence and severity increases with increasing age. About 9.6% report moderate LUTS while 2.3% report severe LUTS. Storage LUTS are reported more frequently than voiding LUTS. LUTS did not vary significantly with BMI, MAC or Wealth-Index. Conclusion LUTS prevalence and severity vary with age, but not with BMI, MAC or Wealth-Index