799 research outputs found
Co-silencing of human Bub3 and dynein highlights an antagonistic relationship in regulating kinetochore-microtubule attachments
We previously reported that the spindle assembly checkpoint protein Bub3 is involved in regulating kinetochore-microtubule (KT-MT) attachments. Also, Bub3 was reported to interact with the microtubule motor protein dynein. Here we examined how this interaction contributes to KT-MT attachments. Depletion of Bub3 or dynein induced misaligned chromosomes, consistent with their role in KT-MT attachments. Unexpectedly, co-silencing of both proteins partially suppressed the misalignment phenotype and restored chromosome congression. Consistent with these observations, KT-MT attachments in co-depleted cells were stable, able to drive chromosome congression, and produce inter-and intra-kinetochore stretch, indicating they are functional. We suggest that a mutual antagonism exists between Bub3 and dynein to ensure optimal KT-MT attachments. (C) 2015 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.CESPU [02-GCQF-CICS-2011N]; FCT - Fundacao para a Ciencia e a Tecnologia [CEQUIMED-PEst-OE/SAU/UI4040/2014]; FCT [SFRH/BD/90744/2012]info:eu-repo/semantics/publishedVersio
Stationary Einstein-Maxwell fields in arbitrary dimensions
The Einstein-Maxwell equations in D-dimensions admitting (D-3) commuting
Killing vector fields have been investigated. The existence of the electric,
magnetic and twist potentials have been proved. The system is formulated as the
harmonic map coupled to gravity on three-dimensional base space generalizing
the Ernst system in the four-dimensional stationary Einstein-Maxwell theory.
Some classes of the new exact solutions have been provided, which include the
electro-magnetic generalization of the Myers-Perry solution, which describes
the rotating black hole immersed in a magnetic universe, and the static charged
black ring solution.Comment: 26 page
c-Axis Transport and Resistivity Anisotropy of Lightly- to Moderately-Doped La_{2-x}Sr_{x}CuO_{4} Single Crystals: Implications on the Charge Transport Mechanism
Both the in-plane and the out-of-plane resistivities (\rho_{ab} and \rho_{c})
are measured in high-quality La_{2-x}Sr_{x}CuO_{4} (LSCO) single crystals in
the lightly- to moderately-doped region, x = 0.01 to 0.10, and the resistivity
anisotropy is determined. In all the samples studied, the anisotropy ratio \rho
_{c}/\rho_{ab} quickly increases with decreasing temperature, although in
non-superconducting samples the strong localization effect causes \rho
_{c}/\rho_{ab} to decrease at low temperatures. Most notably, it is found that
\rho_{c}/\rho_{ab} at moderate temperatures (100 - 300 K) is almost completely
independent of doping in the non-superconducting regime (x = 0.01 to 0.05);
this indicates that the same charge confinement mechanism that renormalizes the
c-axis hopping rate is at work down to x = 0.01. It is discussed that this
striking x-independence of \rho_{c}/\rho_{ab} is consistent with the idea that
holes form a self-organized network of hole-rich regions, which also explains
the unusually metallic in-plane transport of the holes in the lightly-doped
region. Furthermore, the data for x > 0.05 suggest that the emergence of the
superconductivity is related to an increase in the c-axis coupling.Comment: 7 pages, 5 figures, submitted to Phys. Rev.
Effect of a magnetic field on the spin- and charge-density wave order in La1.45Nd0.4Sr0.15CuO4
The spin-density wave (SDW) and charge-density wave (CDW) order in
superconducting La1.45Nd0.4Sr0.15CuO4 were studied under an applied magnetic
field using neutron and X-ray diffraction techniques. In zero field,
incommensurate (IC) SDW order appears below ~ 40 K, which is characterized by
neutron diffraction peaks at (1/2 +/- 0.134, 1/2 +/- 0.134, 0). The intensity
of these IC peaks increases rapidly below T_Nd ~ 8 K due to an ordering of the
Nd^3+ spins. The application of a 1 T magnetic field parallel to the c-axis
markedly diminishes the intensity below T_Nd, while only a slight decrease in
intensity is observed at higher temperatures for fields up to 7 T. Our
interpretation is that the c-axis field suppresses the parasitic Nd^3+ spin
order at the incommensurate wave vector without disturbing the stripe order of
Cu^2+ spins. Consistent with this picture, the CDW order, which appears below
60 K, shows no change for magnetic fields up to 4 T. These results stand in
contrast to the significant field-induced enhancement of the SDW order observed
in superconducting La2-xSrxCuO4 with x ~ 0.12 and stage-4 La2CuO4+y. The
differences can be understood in terms of the relative volume fraction
exhibiting stripe order in zero field, and the collective results are
consistent with the idea that suppression of superconductivity by vortices
nucleates local patches of stripe order.Comment: 7 pages, 5 figure
The Physics of turbulent and dynamically unstable Herbig-Haro jets
The overall properties of the Herbig-Haro objects such as centerline
velocity, transversal profile of velocity, flow of mass and energy are
explained adopting two models for the turbulent jet. The complex shapes of the
Herbig-Haro objects, such as the arc in HH34 can be explained introducing the
combination of different kinematic effects such as velocity behavior along the
main direction of the jet and the velocity of the star in the interstellar
medium. The behavior of the intensity or brightness of the line of emission is
explored in three different cases : transversal 1D cut, longitudinal 1D cut and
2D map. An analytical explanation for the enhancement in intensity or
brightness such as usually modeled by the bow shock is given by a careful
analysis of the geometrical properties of the torus.Comment: 17 pages, 10 figures. Accepted for publication in Astrophysics &
Spac
Resonantly damped surface and body MHD waves in a solar coronal slab with oblique propagation
The theory of magnetohydrodynamic (MHD) waves in solar coronal slabs in a
zero- configuration and for parallel propagation of waves does not allow
the existence of surface waves. When oblique propagation of perturbations is
considered both surface and body waves are able to propagate. When the
perpendicular wave number is larger than a certain value, the body kink mode
becomes a surface wave. In addition, a sausage surface mode is found below the
internal cut-off frequency. When non-uniformity in the equilibrium is included,
surface and body modes are damped due to resonant absorption. In this paper,
first, a normal-mode analysis is performed and the period, the damping rate,
and the spatial structure of eigenfunctions are obtained. Then, the
time-dependent problem is solved, and the conditions under which one or the
other type of mode is excited are investigated.Comment: 19 pages, 9 figures, accepted for publication in Solar Physic
Electron Dynamics in NdCeCuO: Evidence for the Pseudogap State and Unconventional c-axis Response
Infrared reflectance measurements were made with light polarized along the a-
and c-axis of both superconducting and antiferromagnetic phases of electron
doped NdCeCuO. The results are compared to
characteristic features of the electromagnetic response in hole doped cuprates.
Within the CuO planes the frequency dependent scattering rate,
1/, is depressed below 650 cm; this behavior is a
hallmark of the pseudogap state. While in several hole doped compounds the
energy scales associated with the pseudogap and superconducting states are
quite close, we are able to show that in NdCeCuO
the two scales differ by more than one order of magnitude. Another feature of
the in-plane charge response is a peak in the real part of the conductivity,
, at 50-110 cm which is in sharp contrast with the
Drude-like response where is centered at . This
latter effect is similar to what is found in disordered hole doped cuprates and
is discussed in the context of carrier localization. Examination of the c-axis
conductivity gives evidence for an anomalously broad frequency range from which
the interlayer superfluid is accumulated. Compelling evidence for the pseudogap
state as well as other characteristics of the charge dynamics in
NdCeCuO signal global similarities of the cuprate
phase diagram with respect to electron and hole doping.Comment: Submitted to PR
Normal and Lateral Casimir Forces between Deformed Plates
The Casimir force between macroscopic bodies depends strongly on their shape
and orientation. To study this geometry dependence in the case of two deformed
metal plates, we use a path integral quantization of the electromagnetic field
which properly treats the many-body nature of the interaction, going beyond the
commonly used pairwise summation (PWS) of van der Waals forces. For arbitrary
deformations we provide an analytical result for the deformation induced change
in Casimir energy, which is exact to second order in the deformation amplitude.
For the specific case of sinusoidally corrugated plates, we calculate both the
normal and the lateral Casimir forces. The deformation induced change in the
Casimir interaction of a flat and a corrugated plate shows an interesting
crossover as a function of the ratio of the mean platedistance H to the
corrugation length \lambda: For \lambda \ll H we find a slower decay \sim
H^{-4}, compared to the H^{-5} behavior predicted by PWS which we show to be
valid only for \lambda \gg H. The amplitude of the lateral force between two
corrugated plates which are out of registry is shown to have a maximum at an
optimal wavelength of \lambda \approx 2.5 H. With increasing H/\lambda \gtrsim
0.3 the PWS approach becomes a progressively worse description of the lateral
force due to many-body effects. These results may be of relevance for the
design and operation of novel microelectromechanical systems (MEMS) and other
nanoscale devices.Comment: 20 pages, 5 figure
Spectral and transport properties of doped Mott-Hubbard systems with incommensurate magnetic order
We present spectral and optical properties of the Hubbard model on a
two-dimensional square lattice using a generalization of dynamical mean-field
theory to magnetic states in finite dimension. The self-energy includes the
effect of spin fluctuations and screening of the Coulomb interaction due to
particle-particle scattering. At half-filling the quasiparticles reduce the
width of the Mott-Hubbard `gap' and have dispersions and spectral weights that
agree remarkably well with quantum Monte Carlo and exact diagonalization
calculations. Away from half-filling we consider incommensurate magnetic order
with a varying local spin direction, and derive the photoemission and optical
spectra. The incommensurate magnetic order leads to a pseudogap which opens at
the Fermi energy and coexists with a large Mott-Hubbard gap. The quasiparticle
states survive in the doped systems, but their dispersion is modified with the
doping and a rigid band picture does not apply. Spectral weight in the optical
conductivity is transferred to lower energies and the Drude weight increases
linearly with increasing doping. We show that incommensurate magnetic order
leads also to mid-gap states in the optical spectra and to decreased scattering
rates in the transport processes, in qualitative agreement with the
experimental observations in doped systems. The gradual disappearence of the
spiral magnetic order and the vanishing pseudogap with increasing temperature
is found to be responsible for the linear resistivity. We discuss the possible
reasons why these results may only partially explain the features observed in
the optical spectra of high temperature superconductors.Comment: 22 pages, 18 figure
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