DIVERSIFICATION GAINS FOR A HOME BIASED TRADER IN THE EMERGING AND FRONTIER EQUITY MARKETS

We study the case of a home-biased equity trader based in Asia, Central and Eastern Europe, the Middle East and North Africa, or Latin America, who is looking at diversifying his/her investment risks internationally within his/her region and three other emerging/frontier regions. We focus on explaining the dynamic conditional correlations between equity markets from 3 January 2002 to 11 November 2016. Timevarying opportunities for diversification are found in several nations across regions. However, diversification opportunities outside a region are largely reserved for bad times, such as during the global financial crisis and the European sovereign debt crisis

Peripheral Neutrophil to Lymphocyte Ratio (NLR), a cogent clinical adjunct for Ki-67 in breast cancer

Abstract Background Clinical utility of Ki-67 immunohistochemistry (IHC) in breast cancer (BC) is mainly limited to decide for the use of chemotherapy and estimate prognosis in patients with either Ki-67 index  30%; however, lacunae still exists pertaining to its analytical validity. Neutrophilia is common in cancer with accompanying lymphocytopenia. Neutrophil to lymphocyte ratio (NLR) captures the intricate balance between pro-tumor neutrophilia and anti-tumor lymphocyte immunity. This study aimed to correlate cellular proliferation in breast cancer with NLR. Methods An observational study was carried out including 73 cases of BC; pre-treatment NLR and Ki-67 grading were performed. NLR  0.05) and molecular subtype (p > 0.05); however, NLR was found to be significantly correlated with TNM stage (p < 0.001) and Ki-67 (p < 0.001). Conclusion NLR is fast emerging as a personalized theranostic marker in breast cancer. Instead of determining a generalized cut-off value, individual baseline NLR and its dynamics with disease progression will help manage patients better, obviating some of the drawbacks associated with Ki-67

Measurement of relative isotopic yield distribution of even-even fission fragments from 235^{235}U(nthn_{th},ff) following γ\gamma ray spectroscopy

International audienceA detailed investigation on the relative isotopic distributions has been carried out for the first time in case of even-even correlated fission fragments for the U235(nth,f) fission reaction. High-statistics data were obtained in a prompt γ-ray spectroscopy measurement during the EXILL campaign at ILL, Grenoble, France. The extensive off-line analysis of the coincidence data have been carried out using four different coincidence methods. Combining the results from two-dimensional γ-γ and three-dimensional γ-γ-γ coincidence analysis, a comprehensive picture of the relative isotopic yield distributions of the even-even neutron-rich fission fragments has emerged. The experimentally observed results have been substantiated by the theoretical calculations based on a novel approach of isospin conservation, and a reasonable agreement has been obtained. The calculations following the semiempirical GEF model have also been carried out. The results from the GEF model calculations are found to be in fair agreement with the experimental results