319 research outputs found

    The Role of Physiologists in Health Care Delivery Through Exercise

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    Strategies for Enhancing Healthy Sexual Behaviour among Secondary School Adolescents in Nsukka Education Zone of Enugu State Nigeria

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    The study investigated strategies for enhancing health sexual behaviour among secondary school adolescents in Nsukka Education Zone of Enugu State. Two research questions and a hypothesis guided the study. The subjects of the study was 160 secondary school adolescent students. The instrument for data collection was questionnaire. Mean score and t-test statistics were used for data analysis. Results show that adolescents healthy sexual behaviours would be enhanced through emulating healthy sexual behaviours of parents, not watching pornographic films among others. The result of the study also implicated factors such as increase in the rate of abortions among adolescent girls, increase in the spread of sexual transmitted diseases among others as consequences of adolescents’ unhealthy sexual behaviours. The implications of the findings were highlighted and recommendations equally made. Keywords: Strategies, healthy, sexual behavior, adolescent

    Evaluation of binder and disintegrant properties of starch derived from Xanthosoma sagittifolium in metronidazole tablets

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    The aim of the study was to formulate metronidazole tablets using starch from Xanthosoma sagittifolium as binder and disintegrant in metronidazole tablets. Metronidazole tablets were produced by wet granulation method using X. sagittifolium starch as binder at concentrations of 5, 10, 15 and 20% w/w, and as disintegrant (5% w/w). The micromeritic properties of the granules were determined using the direct and indirect methods. The necessary official and non official tests were performed on the tablets to include uniformity of tablets weight, content of active ingredient, disintegration test, hardness, friability tests and in vitro drug release. Also, the phytochemical constituents of the starch were determined. The results show that the granules had a good flow and values obtained were within the specified limits for the production of good quality tablets. Deviations obtained from the tablet weight uniformity test were significantly (p< 0.05) below 5%. Tablets disintegration time ranged from 3.00 ± 0.08 min to 14.00 ± 0.10 min for M1 and M4 tablets formulated with 5 and 20% of X. sagittifolium starch respectively. The tablets hardness ranged from 7.20 ± 1.25 to 8.55 ± 1.17 kgf. In vitro release showed that M1 tablets had T25, T50 and T90 % at 5, 13 and 23 min respectively, while M4 tablets had T25, T50 and T90 % at 8, 18 min and were unable to release 90% of metronidazole at 30 min. Phytochemical analysis showed that the starch contained alkaloids, glycosides, carbohydrate and steroids. Therefore, starch from X. sagittifolium could be used to formulate metronidazole tablets for improved oral bioavailability of metronidazole.Keywords: Xanthosoma sagittifolium starch, tablets binder and disintegrant, metronidazoleAfrican Journal of Biotechnology Vol. 12(20), pp. 3064-307

    Life Cycle Assessment of Environmental Impacts of Using Concrete or Timber to Construct a Duplex Residential Building

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    Traditionally, the choice of construction materials depended principally on the strengths of materials, cost of material, availability of materials, simplicity of erection, aesthetics and technical expertise available to the society. This meant that little attention was paid to the environment impacts of materials adopted for civil construction. After centuries of speedy advancement accompanied by deteriorating ecosystem as evidenced by the global climate change and the accompanying gap between the rich and the poor, the world is becoming more conscious of the ecosystem and the future of mankind. This has led to the growing quest for sustainable development. In the more recent years, environmental and sustainability factors are becoming compelling factors in the choice of construction materials. Researches focused on materials for affordable houses for the increasing low income masses are on the increase. This research focuses on the environmental impact performance of concrete and timber applied to a modest duplex residential building. It explores using Athena Impact Estimator software to model the greenhouses gases expressed in terms of carbon dioxide equivalents, sulphur dioxide equivalents, phosphate equivalents and ethane equivalents potentials obtainable from using concrete or timber to build a duplex residential building. From the various results obtained, it is very evident that timber construction is more eco-friendly in terms of carbon emission reduction which translates to reducing global warming, thermal insulation and energy efficiency. This will be helpful in making choice for building materials to be adopted for affordable houses developing countries

    The moderating role of resilience in the relationship between marital stress and depression

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    The study investigated the moderating role of resilience in the relationship between marital stress and depression among married teachers, with one hundred thirty-five (135) married teachers that comprises of 102 females and 33 males with an age mean of 32.20 and S.D 3.81 selected as participants using multi-stage (cluster, simple: balloting, and purposive) sampling techniques. Zung (1965) Self-rating Depression Scale (SDS), Omoluabi (1994) marital stress Inventory (MSI) and Connor and Davidson (2003). Connor-Davidson Resilience Scale (CD-RISC) were used for data collection, a cross-sectional survey design was adopted, while a moderated hierarchical multiple regression was used for data analysis. The finding shows that marital stress St= .551*** and t= 7.608*** at p< .001 positively predicted depression, Resilience St= -.517*** and t= -6.962*** at p< .001 negatively predicted depression among school teachers and Resilience St= -.748***and t= -7.178*** at p< .001 negatively moderated the relationship between marital stress and depression. Hence, school management can consider hiring psychologists to work with teachers to improve their resilience or educate them on the importance of resilience in managing depression

    Effects of Salt, Detergents and Alum on Fatty Acid Profile in Cooked Eggs

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    In Abakaliki, as in most other parts of Nigeria, it is a common practice among commercial sellers of boiled eggs to boil them with chemicals such as omo, klin, table salt and alum, which gives the egg ashy appearance after cooking.  The effects of cooking with these chemicals on the fatty acid profile of eggs from four species of birds (gallus gallus): Quail (corturnix delegorgei), Guinea fowl (Numida meleagris), local chicken (Gallus varius) and high-breed chicken (Gallus gallus domesticus) were investigated. Fifteen eggs from each bird were bought from various places where they are reared in Abakaliki. Eggs were divided into five groups: A, B, C, D and E, with three eggs in each group. Eggs in groups A, B, C, and D were boiled with omo, klin, table salt and alum, respectively. Group E eggs served as the control group and were boiled with water only. Fatty acid profile was determined using High Performance Liquid Chromatography (HPLC, AKAPTA). The results showed significant (P<0.05) reduction of fatty acids contents of the eggs compared to the control. The effects which were species-dependent were found to be least in the quail egg and highest in the high-bred chicken. The detergents (klin and omo) had more devastating effects compared to alum and table salt. Thus boiling eggs with any of the chemicals studied reduces their nutritional quality and should be discouraged. Keywords: Egg, fatty acid profile, detergents, salt and alu

    Wildlife species diversity indices and seasonal distribution assessment in road-side markets of South-west Nigeria

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    Wildlife species are under serious exploitation by the rural populace in Nigeria because hu­man beings have understood their ecology. The need to update the existing knowledge of wildlife population is therefore essential. Twenty-three games markets along five Roads in South-west Nigeria were visited to document the wildlife displayed for sale. Two hundred and fifty copies of structured questionnaire were administered using systematic random sampling (odd) method for wildlife species information from market stakeholders. Direct method was counting for species and their numbers. Data generated were analysed through Species Diver­sity Indices Assessment. All emergent species were compared with International Union for Conservation of Nature (IUCN) abundance rating. Road seasonal distribution of the marketed wildlife was determined by percentages, standard deviation, standard error of mean, mean differences, t-test, and tests of significance and Diversity Indices. Results revealed that 69,398 wild animals were displayed. Also more wildlife were sold during rainy than dry seasons. Appropriate recommendations of government sensitization of rural and urban settlers against over-utilization of wildlife resources, encouragement of the public towards animal domesti­cation and others were made

    Body Mass Index, Blood Pressure and Serum Cortisol Level as Stress Index in Symptomatic HIV/AIDS Male Subjects on Antiretroviral Therapy Negative to Malaria Parasite in Nnewi, Anambra State, Nigeria

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    Background: HIV infection is a risk factor for a variety of endocrine problems. Objectives: This study investigated the body mass index (BMI), Systolic blood pressure (SBP), Diastolic blood pressure (DBP) and serum cortisol level as stress factor/index symptomatic HIV/AIDS male subjects on ART who are negative to malaria parasite in Nnewi, Anambra State, Nigeria. Methods: A total of 274 adult male participants aged between 18 and 60 (42 ±13) years were randomly recruited at the Voluntary Counseling and Testing (VCT) Centre in Nnamdi Azikiwe University Teaching Hospital and grouped based on WHO criteria for staging HIV into symptomatic HIV (stage 11) infected male participants on ART (A: n=69), Symptomatic HIV subjects not on ART (B: n= 69), Asymptomatic HIV positive subjects (C: n= 68) and HIV seronegative subjects (D: n= 68). Blood samples were collected from the participants for the determination of HIV status by immunochromatography and HIV confirmation by Western Blot. Enzyme-Linked Immunosorbent Assay (ELISA) was used to assay for cortisol level. Results: The results showed a significantly increased BMI and decreased mean serum cortisol level in HIV/AIDS seropositive participants on ART than in those, not on ART (p<0.05). Also, the BMI and mean serum cortisol level were significantly decreased and increased respectively in  HIV/AIDS seropositive participants not on ART than in Asymptomatic HIV positive subjects and control respectively (p<0.05). However, the mean SBP and DBP did not differ significantly between the groups studied (p>0.05). Conclusion: This study revealed a decreased stress index in HIV/AIDS subjects on ART with hypercortisolism and lower BMI in symptomatic HIV participants, not on ART. Keywords: HIV; AIDS; Malaria uninfected male subjects; Cortisol; Blood pressure; Antiretroviral therapy

    Body Mass Index, Blood Pressure and Serum Cortisol Level as Stress Index in Symptomatic HIV/AIDS Male Subjects on Antiretroviral Therapy Negative to Malaria Parasite in Nnewi, Anambra State, Nigeria

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    Background: HIV infection is a risk factor for a variety of endocrine problems. Objectives: This study investigated the body mass index (BMI), Systolic blood pressure (SBP), Diastolic blood pressure (DBP) and serum cortisol level as stress factor/index symptomatic HIV/AIDS male subjects on ART who are negative to malaria parasite in Nnewi, Anambra State, Nigeria. Methods: A total of 274 adult male participants aged between 18 and 60 (42 ±13) years were randomly recruited at the Voluntary Counseling and Testing (VCT) Centre in Nnamdi Azikiwe University Teaching Hospital and grouped based on WHO criteria for staging HIV into symptomatic HIV (stage 11) infected male participants on ART (A: n=69), Symptomatic HIV subjects not on ART (B: n= 69), Asymptomatic HIV positive subjects (C: n= 68) and HIV seronegative subjects (D: n= 68). Blood samples were collected from the participants for the determination of HIV status by immunochromatography and HIV confirmation by Western Blot. Enzyme-Linked Immunosorbent Assay (ELISA) was used to assay for cortisol level. Results: The results showed a significantly increased BMI and decreased mean serum cortisol level in HIV/AIDS seropositive participants on ART than in those, not on ART (p<0.05). Also, the BMI and mean serum cortisol level were significantly decreased and increased respectively in  HIV/AIDS seropositive participants not on ART than in Asymptomatic HIV positive subjects and control respectively (p<0.05). However, the mean SBP and DBP did not differ significantly between the groups studied (p>0.05). Conclusion: This study revealed a decreased stress index in HIV/AIDS subjects on ART with hypercortisolism and lower BMI in symptomatic HIV participants, not on ART. Keywords: HIV; AIDS; Malaria uninfected male subjects; Cortisol; Blood pressure; Antiretroviral therapy
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