Zeolite-dye micro lasers

We present a new class of micro lasers based on nanoporous molecular sieve host-guest systems. Organic dye guest molecules of 1-Ethyl-4-(4-(p-Dimethylaminophenyl)-1,3-butadienyl)-pyridinium Perchlorat were inserted into the 0.73-nm-wide channel pores of a zeolite AlPO$_4$-5 host. The zeolitic micro crystal compounds where hydrothermally synthesized according to a particular host-guest chemical process. The dye molecules are found not only to be aligned along the host channel axis, but to be oriented as well. Single mode laser emission at 687 nm was obtained from a whispering gallery mode oscillating in a 8-$\mu$m-diameter monolithic micro resonator, in which the field is confined by total internal reflection at the natural hexagonal boundaries inside the zeolitic microcrystals.Comment: Accepted for publication in Phys. Rev. Let

Black Hole Lightning from the Peculiar Gamma-Ray Loud Active Galactic Nucleus IC 310

The nearby active galaxy IC 310, located in the outskirts of the Perseus cluster of galaxies is a bright and variable multi-wavelength emitter from the radio regime up to very high gamma-ray energies above 100 GeV. Originally, the nucleus of IC 310 has been classified as a radio galaxy. However, studies of the multi-wavelength emission showed several properties similarly to those found from blazars as well as radio galaxies. In late 2012, we have organized the first contemporaneous multi-wavelength campaign including radio, optical, X-ray and gamma-ray instruments. During this campaign an exceptionally bright flare of IC 310 was detected with the MAGIC telescopes in November 2012 reaching an averaged flux level in the night of up to one Crab above 1 TeV with a hard spectrum over two decades in energy. The intra-night light curve showed a series of strong outbursts with flux-doubling time scales as fast as a few minutes. The fast variability constrains the size of the gamma-ray emission regime to be smaller than 20% of the gravitational radius of its central black hole. This challenges the shock acceleration models, commonly used to explain gamma-ray radiation from active galaxies. Here, we will present more details on the MAGIC data and discuss several possible alternative emission models.Comment: 8 pages, 5 figures, Proceedings of the 34th International Cosmic Ray Conference, 30 July - 6 August, 2015, The Hague, The Netherland

Cellular Automata Simulating Experimental Properties of Traffic Flows

A model for 1D traffic flow is developed, which is discrete in space and time. Like the cellular automaton model by Nagel and Schreckenberg [J. Phys. I France 2, 2221 (1992)], it is simple, fast, and can describe stop-and-go traffic. Due to its relation to the optimal velocity model by Bando et al. [Phys. Rev. E 51, 1035 (1995)], its instability mechanism is of deterministic nature. The model can be easily calibrated to empirical data and displays the experimental features of traffic data recently reported by Kerner and Rehborn [Phys. Rev. E 53, R1297 (1996)].Comment: For related work see http://www.theo2.physik.uni-stuttgart.de/helbing.html and http://traffic.comphys.uni-duisburg.de/member/home_schreck.htm

Insights into the particle acceleration of a peculiar gamma -ray radio galaxy IC 310

IC 310 has recently been identified as a gamma-ray emitter based on observations at GeV energies with Fermi-LAT and at very high energies (VHE, E > 100 GeV) with the MAGIC telescopes. Despite IC 310 having been classified as a radio galaxy with the jet observed at an angle > 10 degrees, it exhibits a mixture of multiwavelength properties of a radio galaxy and a blazar, possibly making it a transitional object. On the night of 12/13th of November 2012 the MAGIC telescopes observed a series of violent outbursts from the direction of IC 310 with flux-doubling time scales faster than 5 min and a peculiar spectrum spreading over 2 orders of magnitude. Such fast variability constrains the size of the emission region to be smaller than 20% of the gravitational radius of its central black hole, challenging the shock acceleration models, commonly used in explanation of gamma-ray radiation from active galaxies. Here we will show that this emission can be associated with pulsar-like particle acceleration by the electric field across a magnetospheric gap at the base of the jet.Comment: 2014 Fermi Symposium proceedings - eConf C14102.

Modeling the water demand on farms

The decreasing availability of water caused by depletion and climate change combined with a growing world population requires the productive use of water now and in the future. The young researcher group "AgroHyd" at the Leibniz-Institute for Agricultural Engineering Potsdam-Bornim (ATB) is currently modeling the water demand for agricultural processes at the farm scale and developing indicators to link the hydrological and agricultural perspectives. The aim of the group is to increase productivity in agriculture by raising water productivity in plant production and livestock farming. The effects of various agronomic measures, individual and in combination, on water productivity are assessed using several indicators. Scenarios of agricultural measures, climate and diets are used to test to what extent the water demand for food production will increase due to growing global change in different regions of the world

BASEWECS - Influence of the Baltic Sea and its annual ice coverage on the water and energy budget of the Baltic Sea

BASEWECS is a contribution to the German Climate Research Program DEKLIM. The project started in May 2001 and lasted until December 2004. BASEWECS aimed at the investigation of the influence of the Baltic Sea and its annual ice coverage on the water and energy budget of the BALTEX are

Leitsymptom Hämatemesis

Eine 62-jährige Patientin wurde notfallmäßig bei Hämatemesis, arterieller Hypotonie, Anämie und hämodynamischer Instabilität auf unsere Intensivstation aufgenommen. Bekannt war eine AL-Amyloidose mit kardialer Beteiligung und Omentuminfiltration. Im Rahmen dieser erhielt die Patientin 6 Tage vor dem Ereignis den zweiten Zyklus Chemotherapie mit Daratumumab und Cyclophosphamid, Bortezomib und Dexamethason. In der Medikation fanden sich Acetylsalicylsäure (ASS) und Apixaban bei Zustand nach akuter Beinischämie links. In der Notaufnahme trat eine weitere akute Hämatemesisepisode mit einem konsekutiven Hämoglobinabfall auf. Zur hämodynamischen Stabilisierung und zur notfallmäßigen endoskopischen Untersuchung und Blutstillung erfolgte die Verlegung auf unsere Intensivstation

Clinical, Endoscopic, and Histopathologic Observations in Gastrointestinal Amyloidosis

Background and Aims: Amyloidosis is a group of systemic disorders caused by extracellular deposition of misfolded serum proteins. Gastrointestinal (GI) involvement is associated with a higher risk of GI bleeding, especially if mucosal lesions are present. Our study aims to evaluate the frequency of GI manifestations in patients with amyloidosis, to clinically characterize these patients and to describe the endoscopic and histopathologic findings in GI amyloidosis. Methods: A retrospective, single-center study of all patients admitted with amyloidosis and GI manifestations was conducted at a German University Hospital between July 2003 and June 2023. Clinical, endoscopic, and histopathological data was retrieved from medical records. Results: Between July 2003 and June 2023, 63 patients with different types of amyloidosis were included into the study. Twenty-three (36,5%) were diagnosed with GI involvement of amyloidosis (60.9% male, median age 62 ± 18.28 years). The distribution of the types of amyloidosis were amyloid light chain (AL) at 52.5%, transthyretin (ATTR) at 21.7%, amyloid A (AA) at 13.0%, and unknown at 18%. Initial GI symptoms were present in 78.3% of the patients and included mainly diarrhea (34.8%), and abdominal pain (30.4%) Affected GI organs were primarily the colon (60,8%) and the stomach (39.1%). Endoscopic findings were ulcerations (47.8%), mucosal inflammation (43.5%), polyps (26.1%), erosions (13.0%), vascular malformation, polypoid protrusion, submucosal hematoma, erythema, metaplasia, and diverticulum. Histopathological findings included vascular wall thickening, (peri-)vascular and interstitial amyloid deposition. Gastrointestinal bleeding occurred in 39.1% of the patients. The mortality rate 5 years after diagnosis was 47.8%. Conclusions: Gastrointestinal amyloidosis can present with multiple symptoms and endoscopic findings, rendering diagnosis a challenge. Of clinical relevance, GI bleeding was a frequent event in our patient cohort. Therefore, clinicians must be aware of GI bleeding as a manifestation of amyloidosis and definite diagnosis should be achieved based on biopsy results