Distributed Methods for High-dimensional and Large-scale Tensor Factorization

Given a high-dimensional large-scale tensor, how can we decompose it into latent factors? Can we process it on commodity computers with limited memory? These questions are closely related to recommender systems, which have modeled rating data not as a matrix but as a tensor to utilize contextual information such as time and location. This increase in the dimension requires tensor factorization methods scalable with both the dimension and size of a tensor. In this paper, we propose two distributed tensor factorization methods, SALS and CDTF. Both methods are scalable with all aspects of data, and they show an interesting trade-off between convergence speed and memory requirements. SALS updates a subset of the columns of a factor matrix at a time, and CDTF, a special case of SALS, updates one column at a time. In our experiments, only our methods factorize a 5-dimensional tensor with 1 billion observable entries, 10M mode length, and 1K rank, while all other state-of-the-art methods fail. Moreover, our methods require several orders of magnitude less memory than our competitors. We implement our methods on MapReduce with two widely-applicable optimization techniques: local disk caching and greedy row assignment. They speed up our methods up to 98.2X and also the competitors up to 5.9X

Early postnatal caloric restriction protects adult male intrauterine growth-restricted offspring from obesity.

Postnatal ad libitum caloric intake superimposed on intrauterine growth restriction (IUGR) is associated with adult-onset obesity, insulin resistance, and type 2 diabetes mellitus (T2DM). We hypothesized that this paradigm of prenatal nutrient deprivation-induced programming can be reversed with the introduction of early postnatal calorie restriction. Ten-month-old male rats exposed to either prenatal nutrient restriction with ad libitum postnatal intake (IUGR), pre- and postnatal nutrient restriction (IPGR), or postnatal nutrient restriction limited to the suckling phase (50% from postnatal [PN]1 to PN21) (PNGR) were compared with age-matched controls (CON). Visceral adiposity, metabolic profile, and insulin sensitivity by hyperinsulinemic-euglycemic clamps were examined. The 10-month-old male IUGR group had a 1.5- to 2.0-fold increase in subcutaneous and visceral fat (P < 0.0002) while remaining euglycemic, insulin sensitive, inactive, and exhibiting metabolic inflexibility (Vo(2)) versus CON. The IPGR group remained lean, euglycemic, insulin sensitive, and active while maintaining metabolic flexibility. The PNGR group was insulin sensitive, similar to IPGR, but less active while maintaining metabolic flexibility. We conclude that IUGR resulted in obesity without insulin resistance and energy metabolic perturbations prior to development of glucose intolerance and T2DM. Postnatal nutrient restriction superimposed on IUGR was protective, restoring metabolic normalcy to a lean and active phenotype

Statistics of unstable periodic orbits of a chaotic dynamical system with a large number of degrees of freedom

For a simple model of chaotic dynamical systems with a large number of degrees of freedom, we find that there is an ensemble of unstable periodic orbits (UPOs) with the special property that the expectation values of macroscopic quantities can be calculated using only one UPO sampled from the ensemble. Evidence to support this conclusion is obtained by generating the ensemble by Monte Carlo calculation for a statistical mechanical model described by a space-time Hamiltonian that is expressed in terms of Floquet exponents of UPOs. This result allows us to interpret the recent interesting discovery that statistical properties of turbulence can be obtained from only one UPO [G. Kawahara and S. Kida, J. Fluid Mech. {\bf 449}, 291 (2001); S. Kato and M. Yamada, Phys. Rev. E {\bf 68}, 025302(R)(2003)].Comment: 4 pages, 1 figure. In order to clarify generality of our result and the role of a large number of degrees of freedom, a brief subsection was adde

Oidium longipes, a new powdery mildew fungus on petunia in the USA: A potential threat to ornamental and vegetable solanaceous crops

This is the first North American report of Oidium longipes, an anamorphic powdery mildew species described recently in Europe. It was found on vegetatively propagated petunia grown in a commercial greenhouse in New Jersey, USA, where it caused a rapidly spreading disease. The pathogen might have originated offshore and may have already been distributed in the United States through horticultural trade. During field surveys in Europe, it was found on petunia in Hungary and Austria as well; this is the first report of O. longipes from these two countries. A detailed light microscopy study of American and European specimens of O. longipes, including freshly collected samples and authentic herbarium specimens, revealed that its conidiophore morphology is more variable than illustrated in the original species description or in subsequent works. Microcycle conidiation, a process not yet known to occur in powdery mildews, was repeatedly observed in O. longipes. The rDNA internal transcribed spacer (ITS) sequences were identical in colonies containing different conidiophore types as well as in a total of five specimens collected from petunia in the United States, Austria, Hungary, Germany, and Switzerland. A phylogenetic analysis of the ITS sequences revealed that the closest known relative of O. longipes is O. lycopersici, known to infect tomato only in Australia. Cross-inoculation tests showed that O. longipes from petunia heavily infected tobacco cv. Xanthi, while the tomato and eggplant cultivars tested were moderately susceptible to this pathogen. These results indicate that its spread represents a potential danger to a number of solanaceous crops. Our ad hoc field surveys conducted in 2006 and 2007 did not detect it outside New Jersey in the United States; all the other powdery mildew–infected petunias, collected in New York and Indiana, were infected by Podosphaera xanthii. In Europe, most of the powdery mildew–infected petunias examined in this study were infected by P. xanthii or Golovinomyces orontii. Our multiple inoculation tests revealed that the same petunia plants and even the same leaves can be infected concomitantly by O. longipes, O. neolycopersici, G. orontii, and P. xanthii. Thus, it is at present unclear to what extent O. longipes contributes to the powdery mildew epidemics that develop year after year on solanaceous plants in many parts of the world

Time-Optimal Adiabatic-Like Expansion of Bose-Einstein Condensates

In this paper we study the fast adiabatic-like expansion of a one-dimensional Bose-Einstein condensate (BEC) confined in a harmonic potential, using the theory of time-optimal control. We find that under reasonable assumptions suggested by the experimental setup, the minimum-time expansion occurs when the frequency of the potential changes in a bang-bang form between the permitted values. We calculate the necessary expansion time and show that it scales logarithmically with large values of the expansion factor. This work is expected to find applications in areas where the efficient manipulations of BEC is of utmost importance. As an example we present the field of atom interferometry with BEC, where the wavelike properties of atoms are used to perform interference experiments that measure with unprecedented precision small shifts induced by phenomena like rotation, acceleration, and gravity gradients.Comment: Submitted to 51st IEEE Conference on Decision and Contro

Approaches to Stretchable Polymer Active Channels for Deformable Transistors

The fabrication of deformable devices has been explored by interconnecting nonstretchable unit devices with stretchable conductors or by developing stretchable unit devices consisting of all stretchable device components such as electrodes, active channels, and dielectric layers. Most researches have followed the first approach so far, and the researches based on the second approach are at the very beginning stage. This paper discusses the perspectives of the second approach, specifically focusing on the polymer semiconductor channel layers, that is expected to facilitate high density device integration in addition to large area devices including polymer solar cells and light-emitting diodes. Three different routes are suggested as separate sections according to the principles imparting stretchability to polymer semiconductor layers: structural configurations of rigid semiconductors, two-dimensional network structure of semiconductors on elastomer substrates, and ductility enhancement of semiconductor films. Each section includes two subsections divided by the methodological difference. This Perspective ends with discussion on the future works for the routes and the challenges related to other device components.112417Ysciescopu

Two Langevin equations in the Doi-Peliti formalism

A system-size expansion method is incorporated into the Doi-Peliti formalism for stochastic chemical kinetics. The basic idea of the incorporation is to introduce a new decomposition of unity associated with a so-called Cole-Hopf transformation. This approach elucidates a relationship between two different Langevin equations; one is associated with a coherent-state path-integral expression and the other describes density fluctuations. A simple reaction scheme $X \rightleftarrows X+X$ is investigated as an illustrative example.Comment: 14page

Local Hall effect in hybrid ferromagnetic/semiconductor devices

We have investigated the magnetoresistance of ferromagnet-semiconductor devices in an InAs two-dimensional electron gas system in which the magnetic field has a sinusoidal profile. The magnetoresistance of our device is large. The longitudinal resistance has an additional contribution which is odd in applied magnetic field. It becomes even negative at low temperature where the transport is ballistic. Based on the numerical analysis, we confirmed that our data can be explained in terms of the local Hall effect due to the profile of negative and positive field regions. This device may be useful for future spintronic applications.Comment: 4 pages with 4 fugures. Accepted for publication in Applied Physics Letter

CTLA-4 rs231775 and risk of acute renal graft rejection: an updated meta-analysis with trial sequential analysis

Contrasting results exist on the association between CTLA-4 rs231775 and acute rejection in kidney transplant recipients. We herein conducted an updated systematic review with meta-analysis and trial sequential analysis (TSA) to clarify this relationship and to establish whether the current evidence is sufficient to draw firm conclusions. In addition, noteworthiness of significant pooled odds ratios (ORs) was estimated by false positive report probability (FPRP). A comprehensive search was performed through PubMed, Web of Knowledge, Cochrane Library and Open Grey up to October 2019. Fifteen independent cohorts, including a total of 5,401 kidney transplant recipients, were identified through the systematic review. Overall, no association was detected with the allelic (OR 1.07, 95% CI 0.88\u20131.30, P = 0.49), dominant (OR 0.94, 95% CI 0.73\u20131.22, P = 0.66) or the recessive (OR 1.18, 95% CI 0.97\u20131.43, P = 0.096) model of CTLA-4 rs231775. In each genetic model, the cumulative Z-curve in TSA crossed the futility boundary and entered the\ua0futility\ua0area. In addition, none of the significant genetic comparisons detected in the subsequent and sensitivity analyses or in previously reported meta-analyses were found to be noteworthy by FPRP. In conclusion, this study provides strong evidence that CTLA-4 rs231775 is not a clinically-relevant genetic risk determinant of acute rejection after renal transplantation