583 research outputs found

    Combined filtering and key-frame reduction of motion capture data with application to 3DTV

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    A new method for combined filtering and key-frame reduction of motion capture data is proposed. Filtering of motion capture data is necessary to eliminate any jitter introduced by a motion capture system. Key-frame reduction, on the other hand, allows animators to easily edit motion data by representing animation curves with a significantly smaller number of key frames. The proposed technique achieves key frame reduction and jitter removal simultaneously by fitting a Hermite curve to motion capture data using dynamic programming. Copyright © UNION Agency - Science Press

    Value of heart-type fatty acid-binding protein (H-FABP) for emergency department patients with suspected acute coronary syndrome.

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    Objective: The aim of this study is testing the value of H-FABP in the early diagnosis of ACS alone or with routinely used biomarkers such as myoglobin, CK-MB, and cTn I in patients who admitted to emergency department (ED) with complaint of chest pain and suspected acute coronary syndrome.Material and Methods: This prospective and cross-sectional study was performed at the Emergency Department of University hospital between June 2009 and September 2010. Patients who were admitted with chest pain within first 48 hours and suspected ACS were enrolled to the study. Blood samples were taken for CK-MB, myoglobin, cTnI and H-FABP The patients were divided into two groups (ACS and non ACS). Statistical analyse were used for relation of biomarkers with diagnosis of ACS.Results: A 66 patients were included to the study. H-FAPB values were positive in15.2% patients. When H-FABP was added to routinely used biomarkers in the diagnosis of ACS, increasing was observed in all sensitivity, specificity, PPV and NPV values. However, this increase was not stastistically significant.Conclusion: H-FABP did not provide any significant change in early diagnosis and exclusion of ACS diagnosis when used either alone or combination with routinely used biomarkersKey Words: heart-type fatty acid-binding protein, acute coronary syndrome, biomarker

    Keyframe reduction techniques for motion capture data

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    Two methods for keyframe reduction of motion capture data are presented. Keyframe reduction of motion capture data enables animators to easily edit motion data with smaller number of keyframes. One of the approaches achieves keyframe reduction and noise removal simultaneously by fitting a curve to the motion information using dynamic programming. The other approach uses curve simplification algorithms on the motion capture data until a predefined threshold of number of keyframes is reached. Although the error rate varies with different motions, the results show that curve fitting with dynamic programming performs as good as curve simplification methods. ©2008 IEEE

    A probable outbreak of toxoplasmosis among boarding school students in Turkey

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    ABSTRACTIn total, 171 students from a boarding school in Izmir, Turkey, with mild and non-specific symptoms of toxoplasmosis, were screened during September–October 2002. All 171 students were seropositive for Toxoplasma gondii IgG and IgM. Of 43 students tested, 40 (93%) had low IgG avidity. None showed evidence of ophthalmic involvement. The data suggest that T. gondii may spread rapidly in close living conditions, possibly following exposure to cat litter. This is the largest recent outbreak of toxoplamosis described in the medical literature

    Relationship among expression of basic-fibroblast growth factor, MTDH/Astrocyte elevated gene-1, adenomatous polyposis coli, matrix metalloproteinase 9,and COX-2 markers with prognostic factors in prostate carcinomas

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    Background: The etiopathogenesis of prostate cancer (PC) is still not clear, but hormonal, genetic, and environmental factors are thought to play a role in the tumor pathogenesis. Astrocyte elevated gene-1(AEG-1) as a novel transmembrane protein is predominantly located in the perinuclear region and endoplasmic reticulum. It has been found that AEG-1 upregulation increases the invasive ability of glioma and prostate cancer. Basic fibroblast growth factor (bFGF), matrix metalloproteinase-9 (MMP-9), cyclooxygenases-2 (COX-2), and adenomatous polyposis coli (APC) are very important in tumor progression as well. Materials and Methods: This study included 97 radical prostatectomy specimens. IHC stains for bFGF, MMP-9, COX-2, APC, and AEG-1 were performed on the tissue microarray using standard procedures. For each patient, the age, Gleason score, tumor volume, lymphovascular invasion, lymph node metastasis, surgical margin, and the invasion of vesiculoseminalis areas were assessed. Analyses were performed using the statistical PASW (ver. 18). Results: Statistically significant positive relationships were found MMP-9 and COX-2 (r = 0.242 and P = 0.017), between MMP-9 and APC (r = 0.207 and P = 0.043), and between bFGF and AEG-1 (r = 0.295 and P = 0.004). However, the relationships between age and staining results and tumor volume and staining results were not found to be significant. Although a positive correlation was found between the Gleason score and tumor volume and the Gleason score and age (r = 0.415 and P = 0.0001; r = 0.246 and P = 0.015, respectively), we did not find a statistically significant relationship between other stains and other prognostic parameters (lymphovascular invasion, lymph node metastasis, surgical margin, or vesiculoseminalis invasion). Conclusion:The relationships we found between MMP-9 and COX-2, between MMP-9, and APC and between bFGF and AEG-1 as independent prognostic parameters could be helpful in the development of new therapeutic procedures.Keywords: Adenomatous polyposis coli, astrocyte elevated gene‑1, basic fibroblast growth factor, cyclooxygenases‑2, matrix metalloproteinase‑9, prognostic parameters, prostate adenocarcinomasNigerian Journal of Clinical Practice • Oct-Dec 2013 • Vol 16 • Issue

    Zero Cosmological Constant and Nonzero Dark Energy from Holographic Principle

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    It is shown that the first law of thermodynamics and the holographic principle applied to an arbitrary large cosmic causal horizon naturally demand the zero cosmological constant and non-zero dynamical dark energy in the form of the holographic dark energy. Semiclassical analysis shows that the holographic dark energy has a parameter d=1d=1 and an equation of state comparable to current observational data, if the entropy of the horizon saturates the Bekenstein-Hawking bound. This result indicates that quantum field theory should be modified at large scale to explain dark energy. The relations among dark energy, quantum vacuum energy and entropic gravity are also discussed.Comment: Revtex 7 pages 2 fig

    Leaf-applied sodium chloride promotes cadmium accumulation in durum wheat grain

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    Cadmium (Cd) accumulation in durum wheat grain is a growing concern. Among the factors affecting Cd accumulation in plants, soil chloride (Cl) concentration plays a critical role. The effect of leaf NaCl application on grain Cd was studied in greenhouse-grown durum wheat (Triticum turgidum L. durum, cv. Balcali-2000) by immersing (10 s) intact flag leaves into Cd and/or NaCl-containing solutions for 14 times during heading and dough stages. Immersing flag leaves in solutions containing increasing amount of Cd resulted in substantial increases in grain Cd concentration. Adding NaCl alone or in combination with the Cd-containing immersion solution promoted accumulation of Cd in the grains, by up to 41%. In contrast, Zn concentrations of grains were not affected or even decreased by the NaCl treatments. This is likely due to the effect of Cl complexing Cd and reducing positive charge on the metal ion, an effect that is much smaller for Zn. Charge reduction or removal (CdCl2 0 species) would increase the diffusivity/lipophilicity of Cd and enhance its capability to penetrate the leaf epidermis and across membranes. Of even more significance to human health was the ability of Cl alone to penetrate leaf tissue and mobilize and enhance shoot Cd transfer to grains, yet reducing or not affecting Zn transfer

    International multicentre study of candida auris infections

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    Background: Candida auris has emerged globally as a multi-drug resistant yeast and is commonly associated with nosocomial outbreaks in ICUs. Methods: We conducted a retrospective observational multicentre study to determine the epidemiology of C. auris infections, its management strategies, patient outcomes, and infection prevention and control practices across 10 centres from five countries. Results: Significant risk factors for C. auris infection include the age group of 61–70 years (39%), recent history of ICU admission (63%), diabetes (63%), renal failure (52%), presence of CVC (91%) and previous history of antibiotic treatment (96%). C. auris was commonly isolated from blood (76%). Echinocandins were the most sensitive drugs. Most common antifungals used for treatment were caspofungin (40%), anidulafungin (28%) and micafungin (15%). The median duration of treatment was 20 days. Source removal was conductedin 74% patients. All-cause crude mortality rate after 30 days was 37%. Antifungal therapy was associated with a reduction in mortality (OR:0.27) and so was source removal (OR:0.74). Contact isolation precautions were followed in 87% patients. Conclusions: C. auris infection carries a high risk for associated mortality. The organism is mainly resistant to most azoles and even amphotericin-B. Targeted antifungal therapy, mainly an echinocandin, and source control are the prominent therapeutic approaches

    Space weather studies of IONOLAB group

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    IONOLAB is an interdisciplinary research group dedicated for handling the challenges of near earth environment on communication, positioning and remote sensing systems. IONOLAB group contributes to the space weather studies by developing state-of-the-art analysis and imaging techniques. On the website of IONOLAB group, www.ionolab.org, four unique space weather services, namely, IONOLAB-TEC, IRI-PLAS-2015, IRI-PLAS-MAP and IRI-PLAS-STEC, are provided in a user friendly graphical interface unit. Newly developed algorithm for ionospheric tomography, IONOLAB-CIT, provides not only 3-D electron density but also tracking of ionospheric state with high reliability and fidelity. The algorithm for ray tracing through ionosphere, IONOLAB-RAY, provides a simulation environment in all communication bands. The background ionosphere is generated in voxels where IRI-Plas electron density is used to obtain refractive index. One unique feature is the possible update of ionospheric state by insertion of Total Electron Content (TEC) values into IRI-Plas. Both ordinary and extraordinary paths can be traced with high ray and low ray scenarios for any desired date, time and transmitter location. 2-D regional interpolation and mapping algorithm, IONOLAB-MAP, is another tool of IONOLAB group where automatic TEC maps with Kriging algorithm are generated from GPS network with high spatio-temporal resolution. IONOLAB group continues its studies in all aspects of ionospheric and plasmaspheric signal propagation, imaging and mapping. © 2016 IEEE

    A review of ECG-based diagnosis support systems for obstructive sleep apnea

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    Humans need sleep. It is important for physical and psychological recreation. During sleep our consciousness is suspended or least altered. Hence, our ability to avoid or react to disturbances is reduced. These disturbances can come from external sources or from disorders within the body. Obstructive Sleep Apnea (OSA) is such a disorder. It is caused by obstruction of the upper airways which causes periods where the breathing ceases. In many cases, periods of reduced breathing, known as hypopnea, precede OSA events. The medical background of OSA is well understood, but the traditional diagnosis is expensive, as it requires sophisticated measurements and human interpretation of potentially large amounts of physiological data. Electrocardiogram (ECG) measurements have the potential to reduce the cost of OSA diagnosis by simplifying the measurement process. On the down side, detecting OSA events based on ECG data is a complex task which requires highly skilled practitioners. Computer algorithms can help to detect the subtle signal changes which indicate the presence of a disorder. That approach has the following advantages: computers never tire, processing resources are economical and progress, in the form of better algorithms, can be easily disseminated as updates over the internet. Furthermore, Computer-Aided Diagnosis (CAD) reduces intra- and inter-observer variability. In this review, we adopt and support the position that computer based ECG signal interpretation is able to diagnose OSA with a high degree of accuracy
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