15,353 research outputs found

    Bexley report: a report to MCCH on a suitable transport policy for its Bexley services

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    This report presents the findings of and recommendations from the study commissioned by MCCH to advise on a comprehensive transport policy for MCCH to use in providing services in both its residential homes and day-care centres in Bexley. It describes the current positions of transport supply for, and of transport demand by the community of people with learning difficulties in the London Borough of Bexley. It also considers the extent to which the transport supply is meeting or not meeting the transport demands and the expressed needs of the people and/or their representatives. The report considers the implications for improvement in transport provision of certain proposed actions by MCCH. Finally, the report presents some recommendations based on a user-centred strategy to help MCCH incorporate their concept of empowering their service users through suitable transport provision. This study has been conducted with the ethos and operational objectives of the MCCH group firmly in mind. MCCH has an objective to enhance quality of life for their service users and is very concerned with ensuring that its service users are enabled to exercise the rights and opportunities of citizenship with particular reference to freedom of choice in time and mode of travel. MCCH holds that real improvement in services to learning disability people must include increased range and choice of people-centred opportunities that address the total needs and aspirations of service users and their carers, underpinned by values and principles of good practice. Thus MCCH desires to put back in the control of users, the lever of decision making as regards services provided to 4 them and intends to do this by actively eliciting user/stakeholders involvement in decision-making. Contrary to the standard social service transport provision style, MCCH desires to create choice for service-users, feeling that people should be able to decide whether, e.g. to go by bus or train and be supported in their decision and not be constrained by the schedule of the provided transport. The specific terms of reference for this study are 1. To examine the current demand for, and provision of, transport within MCCH’s Bexley services. To assess how best these services might be reconfigured and managed, having regard to: · Desire to increase empowerment and choice for service users · Optimizing the integration of the transport management in Bexley within MCCH’s organization, in the light of most efficient use of resources and practice elsewhere in MCCH · Desire to better integrate residential services with day services in Bexley · MCCH’s intention to reconfigure Bexley day services · The move of service users towards ‘supported living’ as opposed to registered care · The objectives and concerns of all parties involved, including Bexley Social Services, Bexley Transport Services, the parents/relatives/carers of the service users and the service users themselves · The way vehicles are currently owned and funded · Efficiency and cost 2. To produce outline proposals, plans and specifications of how a reconfigured transport service would look and operate, including details of resource requirements in enough detail to allow reasonably accurate costing to be derived

    Effects of electron transfer on the stability of hydrogen bonds.

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    The measurement of the dimerization constants of hydrogen-bonded ruthenium complexes (12, 22, 32) linked by a self-complementary pair of 4-pyridylcarboxylic acid ligands in different redox states is reported. Using a combination of FTIR and UV/vis/NIR spectroscopies, the dimerization constants (KD) of the isovalent, neutral states, 12, 22, 32, were found to range from 75 to 130 M-1 (ΔG0 = -2.56 to -2.88 kcal mol-1), while the dimerization constants (K2-) of the isovalent, doubly-reduced states, (12)2-, (22)2-, (32)2-, were found to range from 2000 to 2500 M-1 (ΔG0 = -4.5 to -4.63 kcal mol-1). From the aforementioned values and the comproportionation constant for the mixed-valent dimers, the dimerization constants (KMV) of the mixed-valent, hydrogen-bonded dimers, (12)-, (22)-, (32)-, were found to range from 0.5 × 106 to 1.2 × 106 M-1 (ΔG0 = -7.78 to -8.31 kcal mol-1). On average, the hydrogen-bonded, mixed-valent states are stabilized by -5.27 (0.04) kcal mol-1 relative to the isovalent, neutral, hydrogen-bonded dimers and -3.47 (0.06) kcal mol-1 relative to the isovalent, dianionic hydrogen bonded dimers. Electron exchange in the mixed valence states imparts significant stability to hydrogen bonding. This is the first quantitative measurement of the strength of hydrogen bonds in the presence and absence of electronic exchange

    Automatic analysis of Swift-XRT data

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    The Swift spacecraft detects and autonomously observes ~100 Gamma Ray Bursts (GRBs) per year, ~96% of which are detected by the X-ray telescope (XRT). GRBs are accompanied by optical transients and the field of ground-based follow-up of GRBs has expanded significantly over the last few years, with rapid response instruments capable of responding to Swift triggers on timescales of minutes. To make the most efficient use of limited telescope time, follow-up astronomers need accurate positions of GRBs as soon as possible after the trigger. Additionally, information such as the X-ray light curve, is of interest when considering observing strategy. The Swift team at Leicester University have developed techniques to improve the accuracy of the GRB positions available from the XRT, and to produce science-grade X-ray light curves of GRBs. These techniques are fully automated, and are executed as soon as data are available.Comment: 4 pages, 2 figures, to appear in the proceedings of ADASS XVII (ASP Conference Series

    A synthetic biochemistry platform for cell free production of monoterpenes from glucose.

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    Cell-free systems designed to perform complex chemical conversions of biomass to biofuels or commodity chemicals are emerging as promising alternatives to the metabolic engineering of living cells. Here we design a system comprises 27 enzymes for the conversion of glucose into monoterpenes that generates both NAD(P)H and ATP in a modified glucose breakdown module and utilizes both cofactors for building terpenes. Different monoterpenes are produced in our system by changing the terpene synthase enzyme. The system is stable for the production of limonene, pinene and sabinene, and can operate continuously for at least 5 days from a single addition of glucose. We obtain conversion yields >95% and titres >15 g l-1. The titres are an order of magnitude over cellular toxicity limits and thus difficult to achieve using cell-based systems. Overall, these results highlight the potential of synthetic biochemistry approaches for producing bio-based chemicals

    Evaluating coasean bargaining experiments with meta-analysis

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    While the Coase Theorem has been a touchstone for understanding bargaining behavior, it has also been criticized for relying on unrealistic assumptions. In response, a line of experimental research analyzes bargaining behavior in laboratory settings. This paper uses meta-analysis to evaluate the Coasean bargaining literature by modeling the probability of an efficient bargain as a function of: (1) measures of transaction costs and related variables, and (2) measures of the social dimensions of a bargain. Results suggest that efficient solutions are more likely when explicit transaction costs do not exist, in the absence of a binding time limit, and when participants have perfect information on payoff schedules. Social dimension variables are found to have the potential to affect bargaining outcomes and are an important avenue for further research.Coase Theorem
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