276 research outputs found

    Glove-Box or Desktop Virtual-Reality System

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    The salient features of the optical layout of a desktop-scale virtual-reality system that is specialized for simulating a glove-box work space are depicted and described

    Building Capacity in Nonprofit Organizations

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    Offers a capacity building model that is based on a review of civil society, sustainable development, and organizational management literature. Reviews effective capacity building programs sponsored or operated by foundations. Includes recommendations

    Screening for Diabetes and Pre-Diabetes With Proposed A1C-Based Diagnostic Criteria

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    OBJECTIVE — An International Expert Committee (IEC) and the American Diabetes Asso-ciation (ADA) proposed diagnostic criteria for diabetes and pre-diabetes based on A1C levels. We hypothesized that screening for diabetes and pre-diabetes with A1C measurements would differ from using oral glucose tolerance tests (OGTT). RESEARCH DESIGN AND METHODS — We compared pre-diabetes, dysglycemia (diabetes or pre-diabetes), and diabetes identified by the proposed criteria (A1C 6.5 % for diabetes and 6.0–6.4 % [IEC] or 5.7–6.4 % [ADA] for high risk/pre-diabetes) with standard OGTT diagnoses in three datasets. Non-Hispanic white or black adults without known diabetes who had A1C and 75-g OGTT measurements were included from the prospective Screening for Impaired Glucose Tolerance study (n 1,581), and from the National Health and Nutrition Examination Survey (NHANES) III (n 2014), and NHANES 2005–2006 (n 1,111). RESULTS — OGTTs revealed pre-diabetes in 35.8 % and diabetes in 5.2 % of combined study subjects. A1C provided receiver operating characteristic (ROC) curve areas for diabetes of 0.79– 0.83, but ROC curve areas were 0.70 for dysglycemia or pre-diabetes. The proposed criteria missed 70 % of individuals with diabetes, 71–84 % with dysglycemia, and 82–94 % with pre

    An Analysis of Private School Closings

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    We add to the small literature on private school supply by exploring exits of K-12 private schools. We find that the closure of private schools is not an infrequent event, and use national survey data from the National Center for Education Statistics to study closures of private schools. We assume that the probability of an exit is a function of excess supply of private schools over the demand, as well as the school's characteristics such as age, size, and religious affiliation. Our empirical results generally support the implications of the model. Working Paper 07-0

    Benign Ancient Schwannoma of the abdominal wall: An unwanted birthday present

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    <p>Abstract</p> <p>Background</p> <p>There has been a recent growth in the use of whole body Computerised Tomography (CT) scans in the private sector as a screening test for asymptomatic disease. This is despite scant evidence to show any positive effect on morbidity or mortality. There has been concern raised over the possible harms of the test in terms of radiation exposure as well as the risk and anxiety of further investigation and treatment for the large numbers of benign lesions identified.</p> <p>Case Presentation</p> <p>A healthy 64 year old lady received a privately funded whole body CT scan for her birthday which revealed an incidental mass in the right iliac fossa. This was investigated with further imaging and colonoscopy and as confident diagnosis could not be made, eventually excised. Histology demonstrated this to be a benign ancient schwannoma and we believe this to be the first reported case of an abdominal wall schwannoma in the English literature</p> <p>Conclusions</p> <p>Ancient schwannomas are rare tumours of the peripheral nerve sheaths more usually found in the head, neck and flexor surfaces of extremities. They are a subtype of classical schwannomas with a predominance of degenerative changes. Our case highlights the pitfalls of such screening tests in demonstrating benign disease and subjecting patients to what turns out to be unnecessary invasive investigation and treatment. It provides evidence as to the consequences of the large number of false positive results that are created by blind CT scanning of asymptomatic patients i.e. its tendency to detect pseudodiesease rather than affect survival rates. Should the number of scans increase there may be an unnecessary burden on NHS resources due to the large numbers of benign lesions picked up, that are then referred for further investigation.</p
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