6,568 research outputs found

    The Impact of Contaminated RR Lyrae/Globular Cluster Photometry on the Distance Scale

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    RR Lyrae variables and the stellar constituents of globular clusters are employed to establish the cosmic distance scale and age of the universe. However, photometry for RR Lyrae variables in the globular clusters M3, M15, M54, M92, NGC2419, and NGC6441 exhibit a dependence on the clustercentric distance. For example, variables and stars positioned near the crowded high-surface brightness cores of the clusters may suffer from photometric contamination, which invariably affects a suite of inferred parameters (e.g., distance, color excess, absolute magnitude, etc.). The impetus for this study is to mitigate the propagation of systematic uncertainties by increasing awareness of the pernicious impact of contaminated and radial-dependent photometry.Comment: To appear in ApJ

    Establishing National Ocean Service Priorities for Estuarine, Coastal, and Ocean Modeling: Capabilities, Gaps, and Preliminary Prioritization Factors

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    This report was developed to help establish National Ocean Service priorities and chart new directions for research and development of models for estuarine, coastal and ocean ecosystems based on user-driven requirements and supportive of sound coastal management, stewardship, and an ecosystem approach to management. (PDF contains 63 pages

    Nutrition Derived Advanced Glycation End Products Are Bio-Social Determinants of Health That Inform on Cancer Disparities

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    Objectives Through their ability to perpetuate a reactive stroma, the objective was to define the increased nutritional bioavailability of advanced glycation end products (AGEs) as a pro-tumorigenic consequence of interrelated health inequity risk factors that can influence ancestry specific tumor biology. Methods In vivo, ex vivo, and in vitro models were used to define the molecular effects of nutrition associated AGEs on the ancestry specific tumor microenvironment and tumor growth. Results The PI’s work provides the first in vivo evidence supporting an oncogenic role for AGEs. In mouse allograft models, both the chronic consumption of AGEs and pre-treatment with AGE bound peptide (p\u3c 0.0001) increased prostate tumor growth. In spontaneous tumor models, chronic AGE consumption caused rapid disease progression through prostate intra-epithelial neoplasia (p=0.049) to adenocarcinoma and metastatic disease. Mechanistically, AGEs recapitulated a regulatory program of ‘activated’ stroma similar to that observed in African American prostate tumors. Specifically, increased AGE bioavailability caused receptor for AGE (RAGE) dimerization in resident PCa fibroblasts leading to their activation and the downregulation of matrix regulatory proteins leading to rapid tumor progression. Conclusions When social and biological determinants of health are compromised it may increase nutritional exposure to AGEs and perpetuate a vicious cycle of AGE formation, bioavailability, and pathogenicity. As bio-social determinants of health, AGEs may represent informative and/or functional biomarkers that can be utilized across transdisciplinary studies to address the enduring complexities of cancer disparity

    Anomalous coupling between topological defects and curvature

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    We investigate a counterintuitive geometric interaction between defects and curvature in thin layers of superfluids, superconductors and liquid crystals deposited on curved surfaces. Each defect feels a geometric potential whose functional form is determined only by the shape of the surface, but whose sign and strength depend on the transformation properties of the order parameter. For superfluids and superconductors, the strength of this interaction is proportional to the square of the charge and causes all defects to be repelled (attracted) by regions of positive (negative) Gaussian curvature. For liquid crystals in the one elastic constant approximation, charges between 0 and 4π4\pi are attracted by regions of positive curvature while all other charges are repelled.Comment: 5 pages, 4 figures, minor changes, accepted for publication in Phys. Rev. Let

    Dynamics of a Quantum Reference Frame

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    We analyze a quantum mechanical gyroscope which is modeled as a large spin and used as a reference against which to measure the angular momenta of spin-1/2 particles. These measurements induce a back-action on the reference which is the central focus of our study. We begin by deriving explicit expressions for the quantum channel representing the back-action. Then, we analyze the dynamics incurred by the reference when it is used to sequentially measure particles drawn from a fixed ensemble. We prove that the reference thermalizes with the measured particles and find that generically, the thermal state is reached in time which scales linearly with the size of the reference. This contrasts a recent conclusion of Bartlett et al. that this takes a quadratic amount of time when the particles are completely unpolarized. We now understand their result in terms of a simple physical principle based on symmetries and conservation laws. Finally, we initiate the study of the non-equilibrium dynamics of the reference. Here we find that a reference in a coherent state will essentially remain in one when measuring polarized particles, while rotating itself to ultimately align with the polarization of the particles

    The Period Changes of the Cepheid RT Aurigae

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    Observations of the light curve for the 3.7-day Cepheid RT Aur both before and since 1980 indicate that the variable is undergoing an overall period increase, amounting to +0.082 +-0.012 s/yr, rather than a period decrease, as implied by all observations prior to 1980. Superposed on the star's O-C variations is a sinusoidal trend that cannot be attributed to random fluctuations in pulsation period. Rather, it appears to arise from light travel time effects in a binary system. The derived orbital period for the system is P = 26,429 +-89 days (72.36 +-0.24 years). The inferred orbital parameters from the O-C residuals differ from those indicated by existing radial velocity data. The latter imply the most reasonable results, namely a1 sin i = 9.09 (+-1.81) x 10^8 km and a minimum secondary mass of M2 = 1.15 +-0.25 Msun. Continued monitoring of the brightness and radial velocity changes in the Cepheid are necessary to confirm the long-term trend and to provide data for a proper spectroscopic solution to the orbit.Comment: Accepted for publication in PASP (November 2007

    A Fresh Look at Axions and SN 1987A

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    We re-examine the very stringent limits on the axion mass based on the strength and duration of the neutrino signal from SN 1987A, in the light of new measurements of the axial-vector coupling strength of nucleons, possible suppression of axion emission due to many-body effects, and additional emission processes involving pions. The suppression of axion emission due to nucleon spin fluctuations induced by many-body effects degrades previous limits by a factor of about 2. Emission processes involving thermal pions can strengthen the limits by a factor of 3-4 within a perturbative treatment that neglects saturation of nucleon spin fluctuations. Inclusion of saturation effects, however, tends to make the limits less dependent on pion abundances. The resulting axion mass limit also depends on the precise couplings of the axion and ranges from 0.5x10**(-3) eV to 6x10**(-3) eV.Comment: 32 latex pages, 13 postscript figures included, uses revtex.sty, submitted to Physical Review

    Summer Drivers of Atmospheric Variability Affecting Ice Shelf Thinning in the Amundsen Sea Embayment, West Antarctica

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    Satellite data and a 35-year hindcast of the Amundsen Sea Embayment summer climate using the Weather Research and Forecasting model are used to understand how regional and large-scale atmospheric variability affects thinning of ice shelves in this sector of West Antarctica by melting from above and below (linked to intrusions of warm water caused by anomalous westerlies over the continental shelf edge). El Nino episodes are associated with an increase in surface melt but do not have a statistically significant impact on westerly winds over the continental shelf edge. The location of the Amundsen Sea Low and the polarity of the Southern Annular Mode (SAM) have negligible impact on surface melting, although a positive SAM and eastward shift of the Amundsen Sea Low cause anomalous westerlies over the continental shelf edge. The projected future increase in El Nino episodes and positive SAM could therefore increase the risk of disintegration of West Antarctic ice shelves

    Practical approaches to delivering pandemic impacted laboratory teaching

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    #DryLabsRealScience is a community of practice established to support life science educators with the provision of laboratory-based classes in the face of the COVID-19 pandemic and restricted access to facilities. Four key approaches have emerged from the innovative work shared with the network: videos, simulations, virtual/augmented reality, and datasets, with each having strengths and weaknesses. Each strategy was used pre-COVID and has a sound theoretical underpinning; here, we explore how the pandemic has forced their adaptation and highlight novel utilisation to support student learning in the laboratory environment during the challenges faced by remote and blended teaching
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