247 research outputs found

    An Exploratory Analysis of Father Involvement in Low-Income Families

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    Using data from the Fragile Families study, this paper explores factors that influence paternal involvement in low-income families. 4873 fathers from the Fragile Families study were classified using CART (Classification and Regression Tree Analysis). CART is a nonparametric technique that allows many different factors to be combined in order to classify homogeneous subgroups within a sample. The CART analysis distinguished between residential and non-residential fathers. In addition, among residential fathers, race emerged as the distinguishing factor. For White men, residential status was the only factor to affect involvement. For African American and Hispanic men however, interactions among several sociodemographic characteristics revealed that both contextual and individual factors affect paternal involvement. Results suggest that an ecological approach is necessary in the investigation of paternal involvement.

    The Gloomy Prospect Wins: Statistical Significance and Population Stratification in Genome Wide Association Studies

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    This one-hour lecture by Dr. Eric Turkheimer of the University of Virginia's Department of Psychology explored the following:

The contemporary era has seen a convergence of genomic technology and traditional social scientific concerns with complex human individual differences. Rather than finally turning social science into a replicable hard-scientific enterprise, genomics has gotten bogged down in the long-standing frustrations of social science. A recent report of an extensive genome wide association study of human height demonstrates the profound difficulties of explaining uncontrolled human variation at a genomic level. The statistical technologies that have been brought to bear on the problem of genomic association are simply modifications of similar methods that have been used by social scientists for decades, with little success. The motivation for the statistical methods in genomics is the same as it is in traditional social science: An attempt to discern linear causation in complex systems when experimental control is not possible.

For an audio recording of Dr. Turkheimer's lecture, please visit "http://cirge.stanford.edu/activities/events.html.":http://cirge.stanford.edu/activities/events.htm

    The Costs and Benefits of Lousy Measures of the Environment

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    Offspring ADHD as a risk factor for parental marital problems: Controls for genetic and environmental confounds

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    Background: Previous studies have found that child attention-deficit/hyperactivity disorder (ADHD) is associated with more parental marital problems. However, the reasons for this association are unclear. The association might be due to genetic or environmental confounds that contribute to both marital problems and ADHD. Method: Data were drawn from the Australian Twin Registry, including 1,296 individual twins, their spouses, and offspring. We studied adult twins who were discordant for offspring ADHD. Using a discordant twin pairs design, we examined the extent to which genetic and environmental confounds, as well as measured parental and offspring characteristics, explain the ADHD-marital problems association. Results: Offspring ADHD predicted parental divorce and marital conflict. The associations were also robust when comparing differentially exposed identical twins to control for unmeasured genetic and environmental factors, when controlling for measured maternal and paternal psychopathology, when restricting the sample based on timing of parental divorce and ADHD onset, and when controlling for other forms of offspring psychopathology. Each of these controls rules out alternative explanations for the association. Conclusion: The results of the current study converge with those of prior research in suggesting that factors directly associated with offspring ADHD increase parental marital problems

    Item response theory analysis of the cognitive ability test in TwinLife

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    Carroll S, Turkheimer E. Item response theory analysis of the cognitive ability test in TwinLife. TwinLife Working Paper Series. Vol 02. Bielefeld: Project TwinLife "Genetic and social causes of life chances" (Universität Bielefeld / Universität des Saarlandes); 2018.TwinLife, an ongoing German study of twins and their families, investigates cognitive performance as one factor among many that contribute to the development of social inequality. Participants completed the CFT 20-R, a nonverbal intelligence assessment. The current analysis applied a two-parameter logistic item response theory model using Mplus software to subtest results from twin pairs in the three oldest birth cohorts, ranging in age from 10 to 25 years old. The findings indicated that the 2PL model fit the data considerably better than the one-parameter logistic model did for all four of the CFT 20-R subtests used in TwinLife. Results from the 2PL model, including item and person parameters and test information, are discussed. In addition, the items were assessed for measurement invariance across age cohort and gender. Fit statistics reveal little difference in item function according to these demographic factors, meaning that the CFT 20-R may be valid in heterogeneous samples

    Nature or nurture? Determining the heritability of human striatal dopamine function:an [18F]-DOPA PET study

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    Striatal dopamine function is important for normal personality, cognitive processes and behavior, and abnormalities are linked to a number of neuropsychiatric disorders. However, no studies have examined the relative influence of genetic inheritance and environmental factors in determining striatal dopamine function. Using [18F]-DOPA positron emission tomography (PET), we sought to determine the heritability of presynaptic striatal dopamine function by comparing variability in uptake values in same sex monozygotic (MZ) twins to dizygotic (DZ) twins. Nine MZ and 10 DZ twin pairs underwent high-resolution [18F]-DOPA PET to assess presynaptic striatal dopamine function. Uptake values for the overall striatum and functional striatal subdivisions were determined by a Patlak analysis using a cerebellar reference region. Heritability, shared environmental effects and non-shared individual-specific effects were estimated using a region of interest (ROI) analysis and a confirmatory parametric analysis. Overall striatal heritability estimates from the ROI and parametric analyses were 0.44 and 0.33, respectively. We found a distinction between striatal heritability in the functional subdivisions, with the greatest heritability estimates occurring in the sensorimotor striatum and the greatest effect of individual-specific environmental factors in the limbic striatum. Our results indicate that variation in overall presynaptic striatal dopamine function is determined by a combination of genetic factors and individual-specific environmental factors, with familial environmental effects having no effect. These findings underline the importance of individual-specific environmental factors for striatal dopaminergic function, particularly in the limbic striatum, with implications for understanding neuropsychiatric disorders such as schizophrenia and addictions

    Physiological Correlates of Volunteering

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    We review research on physiological correlates of volunteering, a neglected but promising research field. Some of these correlates seem to be causal factors influencing volunteering. Volunteers tend to have better physical health, both self-reported and expert-assessed, better mental health, and perform better on cognitive tasks. Research thus far has rarely examined neurological, neurochemical, hormonal, and genetic correlates of volunteering to any significant extent, especially controlling for other factors as potential confounds. Evolutionary theory and behavioral genetic research suggest the importance of such physiological factors in humans. Basically, many aspects of social relationships and social activities have effects on health (e.g., Newman and Roberts 2013; Uchino 2004), as the widely used biopsychosocial (BPS) model suggests (Institute of Medicine 2001). Studies of formal volunteering (FV), charitable giving, and altruistic behavior suggest that physiological characteristics are related to volunteering, including specific genes (such as oxytocin receptor [OXTR] genes, Arginine vasopressin receptor [AVPR] genes, dopamine D4 receptor [DRD4] genes, and 5-HTTLPR). We recommend that future research on physiological factors be extended to non-Western populations, focusing specifically on volunteering, and differentiating between different forms and types of volunteering and civic participation

    Associations Between Fast-Food Consumption and Body Mass Index: A Cross-Sectional Study in Adult Twins

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    Obesity is a substantial health problem in the United States, and is associated with many chronic diseases. Previous studies have linked poor dietary habits to obesity. This cross-sectional study aimed to identify the association between body mass index (BMI) and fast-food consumption among 669 same-sex adult twin pairs residing in the Puget Sound region around Seattle, Washington. We calculated twin-pair correlations for BMI and fast-food consumption. We next regressed BMI on fast-food consumption using generalized estimating equations (GEE), and finally estimated the within-pair difference in BMI associated with a difference in fast-food consumption, which controls for all potential genetic and environment characteristics shared between twins within a pair. Twin-pair correlations for fast-food consumption were similar for identical (monozygotic; MZ) and fraternal (dizygotic; DZ) twins, but were substantially higher in MZ than DZ twins for BMI. In the unadjusted GEE model, greater fast-food consumption was associated with larger BMI. For twin pairs overall, and for MZ twins, there was no association between within-pair differences in fast-food consumption and BMI in any model. In contrast, there was a significant association between within-pair differences in fast-food consumption and BMI among DZ twins, suggesting that genetic factors play a role in the observed association. Thus, although variance in fast-food consumption itself is largely driven by environmental factors, the overall association between this specific eating behavior and BMI is largely due to genetic factors
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