5,179 research outputs found

    Heavy Metals Distribution and Pollution in the Sediments of the Wadi Gaza Mouth, Eastern Mediterranean Coast, Palestine

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    Wadi Gaza is the most important wetland in Gaza Strip. Due to the difficult economic conditions, the Israeli occupation and lack of the resources, Wadi Gaza became a place for solid and liquid waste disposal from surrounding provinces. The aim of this study is to assess the heavy metals in the sediments of the Wadi Gaza, North, and South of downstream along the beach of Gaza Strip. This was achieved through sediment sampling along the course of the Wadi downstream; north and south of the beach sands, and the geochemical analysis was done in the Ministry of Health Laboratories. The concentrations of Mn, Zn, Ni, Cd, Cu, and Pb were determined in the sediments, using atomic absorption spectrophotometer

    Some Properties of Thymus Cathepsin D

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    Cathepsin D has been purified from calf thymus using ammonium sulphate precipitation and gel chromatography on Se.phadex G-100. Preparative electrophoresis in polyacrylamide gel, used as the final step in the purification procedure, yielded four active forms of cathepsin D that dissociated further .into several polypepUde bands in the presence of sodium dodecyl sulphate. All four forms were stable over a range of pH from 4-11. They were completely inhibited by pepstatin whereas other metal ions had no appreciable effect upon their activity

    Robot-mediated interviews: : Do robots possess advantages over human interviewers when talking to children with special needs?

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    Wood L.J., Dautenhahn K., Lehmann H., Robins B., Rainer A., Syrdal D.S. (2013) 'Robot-Mediated Interviews: Do Robots Possess Advantages over Human Interviewers When Talking to Children with Special Needs?', In: Herrmann G., Pearson M.J., Lenz A., Bremner P., Spiers A., Leonards U. (eds) Social Robotics. ICSR 2013. Lecture Notes in Computer Science, vol 8239. Springer, Cham Available online at doi: 10.1007/978-3-319-02675-6-6 © Springer-Verlag Berlin Heidelberg 2013Children that have a disability are up to four times more likely to be a victim of abuse than typically developing children. However, the number of cases that result in prosecution is relatively low. One of the factors influencing this low prosecution rate is communication difficulties. Our previous research has shown that typically developing children respond to a robotic interviewer very similar compared to a human interviewer. In this paper we conduct a follow up study investigating the possibility of Robot-Mediated Interviews with children that have various special needs. In a case study we investigated how 5 children with special needs aged 9 to 11 responded to the humanoid robot KASPAR compared to a human in an interview scenario. The measures used in this study include duration analysis of responses, detailed analysis of transcribed data, questionnaire responses and data from engagement coding. The main questions in the interviews varied in difficulty and focused on the theme of animals and pets. The results from quantitative data analysis reveal that the children interacted with KASPAR in a very similar manner to how they interacted with the human interviewer, providing both interviewers with similar information and amounts of information regardless of question difficulty. However qualitative analysis suggests that some children may have been more engaged with the robotic interviewer

    Mice with genetic deletion of group VIA phospholipase A2β exhibit impaired macrophage function and increased parasite load in Trypanosoma cruzi-induced myocarditis

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    Trypanosoma cruzi infection, which is the etiological agent of Chagas disease, is associated with intense inflammation during the acute and chronic phases. The pathological progression of Chagas disease is influenced by the infiltration and transmigration of inflammatory cells across the endothelium to infected tissues, which are carefully regulated processes involving several molecular mediators, including adhesion molecules and platelet-activating factor (PAF). We have shown that PAF production is dependent upon calcium-independent group VIA phospholipase A(2)β (iPLA(2)β) following infection of human coronary artery endothelial cells (HCAECs) with T. cruzi, suggesting that the absence of iPLA(2)β may decrease the recruitment of inflammatory cells to the heart to manage parasite accumulation. Cardiac endothelial cells isolated from iPLA(2)β-knockout (iPLA(2)β-KO) mice infected with T. cruzi demonstrated decreased PAF production compared to that by cells isolated from wild-type (WT) mice but demonstrated increases in adhesion molecule expression similar to those seen in WT mice. Myocardial inflammation in iPLA(2)β-KO mice infected with T. cruzi was similar in severity to that in WT mice, but the iPLA(2)β-KO mouse myocardium contained more parasite pseudocysts. Upon activation, macrophages from iPLA(2)β-KO mice produced significantly less nitric oxide (NO) and caused less T. cruzi inhibition than macrophages from wild-type mice. Thus, the absence of iPLA(2)β activity does not influence myocardial inflammation, but iPLA(2)β is essential for T. cruzi clearance

    Minkowski Tensors of Anisotropic Spatial Structure

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    This article describes the theoretical foundation of and explicit algorithms for a novel approach to morphology and anisotropy analysis of complex spatial structure using tensor-valued Minkowski functionals, the so-called Minkowski tensors. Minkowski tensors are generalisations of the well-known scalar Minkowski functionals and are explicitly sensitive to anisotropic aspects of morphology, relevant for example for elastic moduli or permeability of microstructured materials. Here we derive explicit linear-time algorithms to compute these tensorial measures for three-dimensional shapes. These apply to representations of any object that can be represented by a triangulation of its bounding surface; their application is illustrated for the polyhedral Voronoi cellular complexes of jammed sphere configurations, and for triangulations of a biopolymer fibre network obtained by confocal microscopy. The article further bridges the substantial notational and conceptual gap between the different but equivalent approaches to scalar or tensorial Minkowski functionals in mathematics and in physics, hence making the mathematical measure theoretic method more readily accessible for future application in the physical sciences

    Wildlife and pollution: 2001-02 Annual Report

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    The Wildlife and Pollution contract covers a long-term monitoring programme, the Predatory Bird Monitoring Scheme (PBMS), that examines the levels of certain pollutants in selected wildlife species in Britain. The programme was started in the early 1960s, when there were serious concerns over the effects of organochlorine insecticides and organomercury fungicides on various species of birds and mammals. This early work demonstrated the effects of the organochlorines and eventually contributed to the ban on their use in the UK and abroad. The programme has subsequently assessed the success of these bans by measuring whether there has been a decline in the concentrations of organochlorine pesticides in the livers and eggs of predatory and freshwater fish-eating birds. Investigations have also been made into the levels of industrial polychlorinated biphenyls (PCBs), following their identification as pollutants in 1966. Mercury levels, derived from both agricultural and industrial sources, have also been tracked, although mercury concentrations were not measured in birds collected in 2001. In recent years, investigations have been made into the effects of the newest generation of rodenticides on barn owls Tyto alba. Northern gannet Morus bassanus eggs are also collected approximately biennially from two colonies and, when available, from other sites; eggs were last collected in 2000. This programme is now the longest-running of its kind anywhere in the world and the findings stimulate considerable interest internationally, as well as in Britain. Annual reports give an interim summary of results and every three years these annual results are gathered together into a more substantial report in which they are integrated with previous findings. The latest report of this type covers the period up to and including 2000 (Shore et al. 2005). Results are published periodically in the scientific literature. This current report presents the results of analyses carried out on material collected in 2001. It also includes a review of long-term trends in second-generation anticoagulant rodenticide residues in barn owls that occurred during the monitoring period up to and including the year 2001. The Wildlife and Pollution contract was the subject of scientific assessment within JNCC's rolling programme of peer review in autumn 1993 and was further assessed in 1996. As a result of the last two assessments, some monitoring was curtailed. Most notably, common kestrels Falco tinnunculus are no longer monitored for organochlorines. However, from 2001 onwards, kestrels will be monitored for second-generation anticoagulant rodenticides following the results from an individual study, carried out as part of the PBMS activities, which demonstrated that this species may be particularly vulnerable to exposure to these compounds (Shore et al. 2001). Carcasses and eggs of predatory bird species (such as peregrine falcon Falco peregrinus, common buzzard Buteo buteo, long-eared owl Asio otus, little owl Athene noctua, common kingfisher Alcedo atthis, great crested grebe Podiceps cristatus, and great bittern Botaurus stellaris) which do not form the core part of the PBMS, but are sent to the Centre for Ecology & Hydrology (CEH) by volunteers, are not analysed chemically. However, post-mortem examinations are carried out the carcasses, relevant information is recorded and the cause of death is determined (and reported back to the volunteer who submitted the carcass). Samples of the egg contents and body organs for these species, and samples for the species that do form part of the core monitoring, are all archived at -20°C as part of CEH's unique long-term tissue bank, and are often used in specific targeted research studies in subsequent years. Each section within the Wildlife and Pollution contract is summarised below. Each is dependent on the provision of material from amateur naturalists and other interested parties, and it is not always possible to obtain desired material for analysis, especially from remote areas

    Wildlife and pollution: 2000-01 Annual Report

    Get PDF
    The Wildlife and Pollution contract covers a long-term monitoring programme that examines the levels of certain pollutants in selected wildlife species in Britain. The programme was started in the early 1960s, when there were serious concerns over the effects of organochlorine insecticides and organomercury fungicides on various species of birds and mammals. This early work demonstrated the effects of the organochlorines, and eventually contributed to the ban on their use in the UK and abroad. The programme has measured levels of these compounds in predatory and fish-eating birds since then. Investigations have also been made into the levels of industrial polychlorinated biphenyls (PCBs), following their identification as pollutants in 1966. Mercury levels, derived from both agricultural and industrial sources, have also been tracked. In recent years, investigations have been made into the effects of the latest generation of rodenticides on barn owls Tyto alba. Northern gannet Morus bassanus eggs are also collected approximately biennially from two colonies and, when available, from other sites; eggs were collected from one site in 2000. This programme is now the longest-running of its kind anywhere in the world and the findings stimulate considerable interest internationally, as well as in Britain. Annual reports give an interim summary of results. This current report presents the results of analyses carried out on material collected in 2000. Every three years these annual results are gathered together into a more substantial report in which they are integrated with previous findings. The last report of this type covered the period up to and including 1997 (Newton et al. 1998) and is updated here. The present report summarises the long-term trends in all contaminants (except rodenticides, analysed in Shore et al. 2005) that occurred during the monitoring period up to and including the year 2000. Results are published periodically in the scientific literature, and recent key papers are listed in the references to the present report. The Wildlife and Pollution contract was the subject of scientific assessment within JNCC's rolling programme of peer review in autumn 1993 and was further assessed in 1996. As a result of the last two assessments, some monitoring was curtailed. Specifically, common kestrels Falco tinnunculus were no longer monitored for organochlorines, although from 2001 this species will be monitored annually for second-generation anticoagulant rodenticides. The Centre for Ecology & Hydrology (CEH) still collects specimens for studying other contaminants as part of its core research programme. Similarly, other species (peregrine falcon Falco peregrinus, common buzzard Buteo buteo, long-eared owl Asio otus, little owl Athene noctua, common kingfisher Alcedo atthis, great crested grebe Podiceps cristatus, and great bittern Botaurus stellaris) that were received in small numbers in occasional years were also not analysed routinely, although some were analysed in specific one-off studies and tissues from all birds received at CEH in 2000 are archived in deep-freeze for future potential analyses. Each section within the Wildlife and Pollution contract is summarised below. Each is dependent on the provision of material from amateur naturalists and other interested parties, and it is not always possible to obtain desired material for analysis, especially from remote areas

    An examination of the psychometric structure of the Multidimensional Pain Inventory in temporomandibular disorder patients: a confirmatory factor analysis

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    BACKGROUND: This paper seeks to analyse the psychometric and structural properties of the Multidimensional Pain Inventory (MPI) in a sample of temporomandibular disorder patients. METHODS: The internal consistency of the scales was obtained. Confirmatory Factor Analysis was carried out to test the MPI structure section by section in a sample of 114 temporomandibular disorder patients. RESULTS: Nearly all scales obtained good reliability indexes. The original structure could not be totally confirmed. However, with a few adjustments we obtained a satisfactory structural model of the MPI which was slightly different from the original: certain items and the Self control scale were eliminated; in two cases, two original scales were grouped in one factor, Solicitous and Distracting responses on the one hand, and Social activities and Away from home activities, on the other. CONCLUSION: The MPI has been demonstrated to be a reliable tool for the assessment of pain in temporomandibular disorder patients. Some divergences to be taken into account have been clarified
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