Evalution of Neutrophil/Leucocyte ratio, Immunoglobulin M (IgM) and Immunoglobulin G (IgG) Levels in acute myocardial infarction

Akut miyokard infarktüsü (AMI) vakalarında yapılan bazı rutin hematolojik parametrelerin öneminin yanı sıra immünoglobulin düzeyleriyle ilgili farklı sonuçlar bulunmaktadır. Bu çalışmada; AMI hastalarının total immunoglobulin IgM ile total IgG seviyesi,lökosit, nötrofil, ve lenfosit sayıları, nötrofil/lenfosit (N/L) oranı gibi hematolojik parametrelerin tesbiti,, bu parametreler arasındaki farkın ve ilişkinin araştırılması amaçlandı. Gereç ve yöntem: Acil servise başvurup Kardiyoloji Yoğun bakım Ünitesine (YBÜ) yatırılan 54 AMI hastası (22 bayan, 32 erkek) ve kardiyak herhangi bir sorunu bulunmayan 54 sağlıklı kişi (25 bayan, 29 erkek) çalışmaya dahil edildi. Şikayetlerinin ilk 24 saati içinde bulunan MI hastalarından ve sağlıklı kişilerden biyokimya tüpüne ve EDTA’lı tüpe periferik venöz kan örnekleri alındı. EDTA’lı tüpe alınan tam kan numunesinden hematolojik ölçümler gerçekleştirilirken, biyokimya tüpüne alınan kan numunesinden total IgM ve total IgG düzeyi analizleri yapıldı. Bulgular: AMI hastalarında, kontrole kıyasla lökosit sayısı, nötrofil sayısı ve N/L oranı anlamlı olarak yüksek saptanırken, IgM ve IgG seviyelerinde anlamlı farklılık saptanmadı. ST yükselmeli miyokard infarktüsü (STEMI) olanlarda, ST yükselmesiz miyokard infarktüsü (NSTEMI) olanlara kıyasla lökosit ve nötrofil sayısı anlamlı olarak yüksek saptandı. Anjiyoplasti yapılanlarda, yapılmayanlara kıyasla lökosit sayısı anlamlı olarak yüksek saptandı. AMI hastalarında ve kontrol bireylerinde, total IgM ve total IgG seviyelerinin hematolojik parametrelerle ilişkisinin olmadığı da bulundu. Sonuç: IgM ve IgG düzeyleriyle ilgili literatürde tartışmalı durum devam ederken lökosit sayısı, nötrofil sayısı ve N/L oranı AMI hastalığının ilk saatlerinde önemini korumakta olup anjiyoplastinin erken uygulanması hususunda yardımcı olabilir.Besides importance of some routine parameters, different studies reported inconsistent immunoglobulin M (IgM) and immunoglobulin G(IgG) levels in acute myocardial infarction (AMI) cases. Therefore, in this study, the objective was to investigate total IgM and IgG levels and hematological parameters including leukocyte, neutrophil and lymphocyte. The relationship and differences between these parameters were also evaluated. Material and methods: A total of 54 AMI patients (22 female and 32 male) who were admitted to the emergency room and then serviced cardiology intensive care unit and 54 healthy people (25 female and29 male) having no known cardiac problems were included into the study. Peripheral venous blood samples were withdrawn into the biochemical and EDTA tubes from the MI patients within the first 24 hours of complains started and also from the healthy group. Whole blood samples with EDTA were used for hematological analyses and biochemical tubes were used for analysis of total IgM and IgG levels. Results: In AMI patients, leukocyte, neutrophil counts and N/L ratio were significantly increased comparing to the control group. However, no differences were observed for IgM and IgG levels. Comparing to the Non ST elevation miyocardial infarction( NSTEMI), leukocyte and neutrophile counts were significantly higher in the ST elevation miyocardial infarction (STEMI )group. Patients who were angioplasty performed leukocyte numbers were significantly higher than patient having no angioplasty. It was also observed that levels of IgM and IgM were related with the hematological parameters in AMI patients and control group. Conclusion: In literature, there is still a conflict for IgM and IgG levels. However, leukocyte and neutrophil counts and N/L ratios were critically important in first hours of AMI cases and can be useful for decision of early angioplasty applications

İran nükleer anlaşması, Ortadoğu'da güç dengesi ve Türkiye (Iran nuclear deal, balance of power in the Middle East and Turkey)

Değişen Ortadoğu dengeleri ve Batı ile İran’ın uzlaşma girişimleri, Türk dış politikasının uluslararası alanda daha aktif bir rol üstlenmesine katkıda bulunabilir ve Ankara’nın dış politika vizyonunu yeniden yapılandırmaya çalıştığı bir zamanda Türkiye’nin bölgesel etkisini arttırabilir

Treatment of renal stones with flexible ureteroscopy in preschool age children

WOS: 000336383500008PubMed ID: 24374900The aim of the study is to evaluate the efficacy and safety of retrograde intrarenal surgery (RIRS) to treat renal stones in preschool age ( 4 mm, a second-stage RIRS was performed. The pre-operative, operative and post-operative data of the patients were retrospectively analyzed. A total of 65 patients with a mean age of 4.31 +/- A 1.99 years (6 months-7 years) were included in the present study. The mean stone size was 14.66 +/- A 6.12 mm (7-30 mm). The mean operative time was 46.47 +/- A 18.27 min. In 5 (7.69 %) patients, the initial procedure failed to reach the renal collecting system and ended with the insertion of a pigtail stent. The stone-free rates were 83.07 and 92.3 % after the first and second procedures, respectively. Complications were observed in 18 (27.7 %) patients and classified according to the Clavien system. Post-operative hematuria (Clavien I) occurred in 6 (9.2 %) patients, post-operative urinary tract infection with fever (Clavien II) was observed in 10 (15.4 %) patients, and ureteral wall injury (Clavien III) was noted in 2 (3 %) patients. RIRS is an effective and safe procedure that can be used to manage renal stones in preschool age children

DIFFERING IN AGRONOMIC AND QUALITY CHARACTERS IN SOME BACKCROSS–DERIVED LINES IN BREAD WHEAT (Triticum aestivum L.) GENOTYPES

The backcrossing method remains an efficient tool for transferring genes into established crop varieties. In this study; we were focused on evaluating the selected some backcross lines for yield, grain-quality traits and some agronomic traits under field condition. The experiment was conducted using 15 genotypes in randomized completely blocks design with four replications in Trakya ARI experimental field, during 2009-2010 and 2010-2011 growing years. Grain yield, days of heading and maturing, plant height and some quality parameters and relationship among these parameters were investigated. According to results, there was statistically difference among genotypes in terms of yield and other investigated characters, except for 1000-kernel weight, test weight. Grain yields decreased in Pehlivan, Aldane, Tekirdağ and Dropia backcross lines. It was determined that TKW increased in the backcross derived lines of the Gelibolu, Dropia and Prostor, gluten value increased in Pehlivan and Tekirdağ cultivars. Backcross line for gluten index of the Pehlivan, Aldane, Gelibolu, Prostor and Dropia cultivars highly increased compared with other components. Sedimentation values of the backcross lines of cultivars decreased in Prostor and increased in Pehlivan, Gelibolu and Dropia. The strongly negative correlations were measured between grain yield and days of maturing (r=-0.689**), plant height (r=-0.655**), and lodging resistant (r=-0.743**). Also, grain yield was negatively correlated with protein ratio (r=-0.608*), gluten value (r=-0.541*), and days of heading (r=-0.607*). The negative correlations were found between grain yield and 1000-kernel weight, test weight, hardness, sedimentation, and winter-kill, as well. The strong positive correlations were measured between protein ratio and gluten, hardness, sedimentation, days of heading and maturing, plant height, and lodging resistant. Grain hardness in genotypes increased with the extension of maturation period of the genotypes. Plant height in genotypes strongly correlated with grain yield, protein ratio, gluten value, gluten index, days of heading and maturing

EFFECT OF BIOMASS AT DIFFERENT GROWTH STAGE ON GRAIN YIELD AND QUALITY IN BREAD WHEAT (Triticum aestivum L.) GENOTYPES

The aim of this research was to determine the effects of location, genotypes and the interaction of location x genotypes on biomass, canopy temperature, yield and some of the quality traits of the bread wheat genotypes under field conditions. Thus, it was established with 25 genotypes in randomized completely blocks design with 4 replications at 3 locations in Trakya Region, Turkey, in 2013-2014 growing season. Grain yield, biomass, canopy temperature, plant height, 1000-kernel weight, test weight, and relationship among these characters were investigated. For determining biomass of the genotypes, data was taken at three plant growth stages; tillering, shooting and heading. Combined analysis of variance across three locations revealed highly significant variation among wheat genotypes for grain yield, biomass of stem elongation, heading stage and canopy temperature. The mean yield of the genotypes was 723.0 kg da-1, and the highest yields were obtained from Entry 22 with 826.3 kg da-1. The highest biomass was scaled in Entry-9 during threeplant growth stages. Additionally, a positive correlation was observed between grain yield and biomass in tillering, shooting, and heading growth stages of the genotypes. These results indicated that higher biomass at early plant growth stage was more significant for yield potential. There was detected slightly negative relationship between canopy temperature and biomass, and grain yield. It could be that the canopy temperatures of genotypes were measured lower during the increasing of biomass in plant development. During tillering stage, higher biomass promoted to plant height and positively affected protein ratio, values of gluten and sedimentation. In shooting phase of genotypes, biomass positively affected and increased in 1000-kernel weight, protein ratio, gluten value and sedimentation value, as well. But increasing in biomass during heading stage, negatively affected and decreased in canopy temperature, 1000-kernel weight, test weight, protein ratio, gluten index and sedimentation value

The effectiveness of BD Vacutainer® Plus Urinalysis Preservative Tubes in preservation of urine for chemical strip analysis and particle counting.

Introduction: The aim of this study was to evaluate the stability of urine collected in preservative tubes for chemistry strip analyses and particle counting to determine whether the transport of urine samples with all of their constituents is possible. Materials and methods: 275 pathologic urine specimens were included. Each urine sample was evaluated after 4, 8, 12, 24, and 48 hours of storage in BD Vacutainer® Plus Urinalysis Preservative (BD UAP) tubes and compared with refrigeration at 4 °C. All analyses were peformed on H-800 and FUS-200 automatic modular urine analyzers (Dirui Industry, Changchun, China). The kappa coefficients (?), false positive (FP) and false negative (FN) rates were evaluated. ? > 0.8 was accepted as good agreement. Results: Haemoglobin (Hb), leucocyte esterase (LE), and protein (Pro) analyses should be performed within 4 hours, whereas glucose (Glc) was stable until the end of 48 hours in both storage conditions. Nitrite (Nit) was well preserved in BD UAP tubes for 24 hours but was stable only up to 8 hours at 4 °C. Bilirubin (Bil) had very high FN rates even at 4 hours in both conditions. The particle counting showed high FN rates for white blood cells (WBC) and red blood cells (RBC), whereas squamous epithelial cells (EC) were stable up to 8 hours in both conditions. Conclusions: Preanalytical requirements for both urine chemical strip analyses and particle counting in a unique sample were not met in either condition. Thus, the transfer of urine samples for centralization of urinalysis is not yet feasible

The Diagnostic Value of Brush Cytology Alone and in Combination with Tumor Markers in Pancreaticobiliary Strictures

Aim. Differentiation of malignant and benign strictures constitutes a problem despite the increasing experience of the endoscopists, radiologists, and pathologists. The aim of our study is to determine the factors that affect the efficacy of the ERCP guided brush cytology in PBS and to evaluate its diagnostic success when used alone and together with tumor markers. Method. The data from brush cytologies of 301 PBS patients were collected retrospectively and analyzed. The final diagnosis was approved based on the histological examination of the tissue taken surgically or by other methods. In the absence of a histological diagnosis, the final diagnosis was based on radiological studies or the results of a 12-month clinical follow up. Results. A total of 28 patients were excluded from the study. From the remaining 273 patients 299 samples were analyzed. The sensitivity and the specificity of brush cytology in diagnosing malignancy are 62.4% and 97.7, respectively. The sensitivity of brush cytology increased to 94.1% when combined with CA-19.9 and CA-125. Conclusion. Brush cytology is a useful method in diagnosing pancreaticobiliary strictures. Advanced age, stricture dilatation before sampling, the presence of a mass identified by radiological studies, high levels of CA-19.9, ALT, and total bilirubin increase the sensitivity of brush cytology

Triple-Divided Concha Bullosa: A New Anatomic Variation

In recent years, with the widespread use of imaging techniques such as paranasal sinus computed tomography (CT), many variations of nasal turbinates have been described. One of these variations known as concha bullosa (CB) is pneumatization of nasal turbinates. CB is the most frequently encountered anatomical variations of the middle turbinate. The term of septated concha bullosa has been described recently and it is an uncommon pneumatization anomaly of the middle turbinate. There has not been any study that correlates the number of septations and the presence of sinonasal pathologies. We hereby present a case of triple septated concha bullosa that has not been reported so far