4,552 research outputs found

    Deriving preference-based single indices from non-preference based condition-specific instruments: converting AQLQ into EQ5D indices

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    Suppose that one has a clinical dataset with only non-preference-based QOL data, and that one nevertheless would like to perform a cost/QALY analysis. This study reports on some efforts to establish a “mapping” relationship between AQLQ (a non-preference-based QOL instrument for asthma) and EQ5D (a preference-based generic instrument). Various methods are described in terms of associated assumptions regarding the measurement properties of the instruments. This is followed by empirical mapping, based on regressing EQ5D on AQLQ. Six main regression models and two supplementary models are identified, and the regressions carried out. Performance of each model is explored in terms of goodness of fit between observed and predicted values, and of robustness of predictions on external data. The results show that it is possible to predict mean EQ5D indices given AQLQ data. The general implications for methods of mapping non-preference-based instruments onto preference-based measures are discussed.EQ5D; AQLQ; mapping

    Deriving preference-based single indices from non-preference based condition-specific instruments: Converting AQLQ into EQ5D indices

    Get PDF
    Suppose that one has a clinical dataset with only non-preference-based QOL data, and that one nevertheless would like to perform a cost/QALY analysis. This study reports on some efforts to establish a "mapping" relationship between AQLQ (a non-preference-based QOL instrument for asthma) and EQ5D (a preference-based generic instrument). Various methods are described in terms of associated assumptions regarding the measurement properties of the instruments. This is followed by empirical mapping, based on regressing EQ5D on AQLQ. Six main regression models and two supplementary models are identified, and the regressions carried out. Performance of each model is explored in terms of goodness of fit between observed and predicted values, and of robustness of predictions on external data. The results show that it is possible to predict mean EQ5D indices given AQLQ data. The general implications for methods of mapping non-preference-based instruments onto preference-based measures are discussed

    Superfluidity of Dirac Fermions in a Tunable Honeycomb Lattice: Cooper Pairing, Collective Modes, and Critical Currents

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    Motivated by recent experiments on atomic Dirac fermions in a tunable honeycomb optical lattice, we study the attractive Hubbard model of superfluidity in the anisotropic honeycomb lattice. At weak-coupling, we find that the maximum mean field pairing transition temperature, as a function of density and interaction strength, occurs for the case with isotropic hopping amplitudes. In this isotropic case, we go beyond mean field theory and study collective fluctuations, treating both pairing and density fluctuations for interaction strengths ranging from weak to strong coupling. We find evidence for a sharp sound mode, together with a well-defined Leggett mode over a wide region of the phase diagram. We also calculate the superfluid order parameter and collective modes in the presence of nonzero superfluid flow. The flow-induced softening of these collective modes leads to dynamical instabilities involving stripe-like density modulations as well as a Leggett-mode instability associated with the natural sublattice symmetry breaking charge-ordered state on the honeycomb lattice. The latter provides a non-trivial test for the experimental realization of the one-band Hubbard model. We delineate regimes of the phase diagram where the critical current is limited by depairing or by such collective instabilities, and discuss experimental implications of our results.Comment: 20 pages, 12 figures. v3: published versio

    Damping of Bogoliubov Excitations in Optical Lattices

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    Extending recent work to finite temperatures, we calculate the Landau damping of a Bogoliubov excitation in an optical lattice, due to coupling to a thermal cloud of such excitations. For simplicity, we consider a 1D Bose-Hubbard model and restrict ourselves to the first energy band. For energy conservation to be satisfied, the excitations in the collision processes must exhibit ``anomalous dispersion'', analogous to phonons in superfluid 4He^4\rm{He}. This leads to the disappearance of all damping processes when Unc0≥6tU n^{\rm c 0}\ge 6t, where UU is the on-site interaction, tt is the hopping matrix element and nc0(T)n^{\rm c 0}(T) is the number of condensate atoms at a lattice site. This phenomenon also occurs in 2D and 3D optical lattices. The disappearance of Beliaev damping above a threshold wavevector is noted.Comment: 4pages, 5figures, submitted to Phys. Rev. Let

    Theoretical determination of the Raman spectra of MgSiO3 perovskite and post-perovskite at high pressure

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    We use the density functional perturbation theory to determine for the first time the pressure evolution of the Raman intensities for a mineral, the two high-pressure structures of MgSiO3 perovskite and post-perovskite. At high pressures, the Raman powder spectra reveals three main peaks for the perovskite structure and one main peak for the post-perovskite structure. Due to the large differences in the spectra of the two phases Raman spectroscopy can be used as a good experimental indication of the phase transition.Comment: 16 pages, submitted to Geophysical Research Letter

    Large N reduction on group manifolds

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    We show that the large N reduction holds on group manifolds. Large N field theories defined on group manifolds are equivalent to some corresponding matrix models. For instance, gauge theories on S^3 can be regularized in a gauge invariant and SO(4) invariant manner.Comment: 21 pages, 4 figures, typos corrected, a reference adde

    Spectral Decomposition of Path Space in Solvable Lattice Model

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    We give the {\it spectral decomposition} of the path space of the U_q(\hatsl) vertex model with respect to the local energy functions. The result suggests the hidden Yangian module structure on the \hatsl level ll integrable modules, which is consistent with the earlier work [1] in the level one case. Also we prove the fermionic character formula of the \hatsl level ll integrable representations in consequence.Comment: 27 pages, Plain Tex, epsf.tex, 7 figures; minor revision. identical with the version to be published in Commun.Math.Phy

    M5-brane Effective Action as an On-shell Action in Supergravity

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    We show that the covariant effective action for M5-brane is a solution to the Hamilton-Jacobi (H-J) equations of 11-dimensional supergravity. The solution to the H-J equations reproduces the supergravity solution that represents the M2-M5 bound states.Comment: 20 pages, references added, typos correcte

    Microwave vortex dynamics in Tl-2212 thin films

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    We present measurements of the effective surface impedance changes due to a static magnetic field, \Delta Z(H,T)=\Delta R(H,T)+\rmi \Delta X(H,T), in a Tl-2212 thin film with Tc>T_c> 103 K, grown on a CeO2_2 buffered sapphire substrate. Measurements were performed through a dielectric resonator operating at 47.7 GHz, for temperatures 60 K≤T<Tc\leq T<T_c and magnetic fields ≤0.8\leq0.8 T. We observe exceptionally large field induced variations and pronounced super-linear field dependencies in both ΔR(H)\Delta R(H) and ΔX(H)\Delta X(H) with ΔX(H)>ΔR(H)\Delta X(H)>\Delta R(H) in almost the whole (H,T)(H,T) range explored. A careful analysis of the data allows for an interpretation of these results as dominated by vortex dynamics. In the intermediate-high field range we extract the main vortex parameters by resorting to standard high frequency model and by taking into proper account the creep contribution. The pinning constant shows a marked decrease with the field which can be interpreted in terms of flux lines softening associated to an incipient layer decoupling. Small vortex viscosity, by an order of magnitude lower than in Y-123 are found. Some speculations about these findings are provided.Comment: pdfTeX, 4 pages, 3 figures, VORTEX 2007 proceedings, to appear in Physica

    Remarks on the structure constants of the Verlinde algebra associated to sl3sl_3

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    The structure constants Nλ,μμ+νN_{\lambda, \mu}^{\mu+\nu} of the sl2sl_2 Verlinde algebra as functions of μ\mu either vanish or can be expressed after a change of variable as the weight function of an irreducible representation of sl2sl_2. We give a similar formula in the sl3sl_3 case.Comment: 5 pages, AmsTeX, 1 figure available on reques
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