10,647 research outputs found
Study of the Brazil and Falkland currents using their images of Nimbus 5 and oceanographic data in 1972 - 1973
The Western Edge of the Sub-tropical Convergence of the South-western Atlantic Ocean, called the Front, which is a thermal discontinuity between the Brazil and Falkland Currents, was studied utilizing the Temperature Humidity Infrared Radiometer (THIR) of Nimbus V in the 10.5 to 12.5 micrometers channel and historical oceanographic data. Some important results obtained are: the oceanographic Front could be detected from Nimbus THIR data; oceanographic charts showed that the transition zone where the Brazil and the Falkland Currents meet was the Front detected from satellite data; ocean current speeds calculated with THIR data were of the same order of magnitude as those calculated oceanographically; fisheries statistics for Pargo Roseo showed that the maximum catches were in September of 1973, in the period when the Front was observed most distinctly and clearly. The results showed the great potentiality of satellite data to study surface thermal structures, surface currents and oceanic fisheries
Neutron spin-echo study of the critical dynamics of spin-5/2 antiferromagnets in two and three dimensions
We report a neutron spin-echo study of the critical dynamics in the
antiferromagnets MnF and RbMnF with three-dimensional (3D) and
two-dimensional (2D) spin systems, respectively, in zero external field. Both
compounds are Heisenberg antiferromagnets with a small uniaxial anisotropy
resulting from dipolar spin-spin interactions, which leads to a crossover in
the critical dynamics close to the N\'eel temperature, . By taking
advantage of the energy resolution of the spin-echo
spectrometer, we have determined the dynamical critical exponents for both
longitudinal and transverse fluctuations. In MnF, both the characteristic
temperature for crossover from 3D Heisenberg to 3D Ising behavior and the
exponents in both regimes are consistent with predictions from the
dynamical scaling theory. The amplitude ratio of longitudinal and transverse
fluctuations also agrees with predictions. In RbMnF, the critical
dynamics crosses over from the expected 2D Heisenberg behavior for
to a scaling regime with exponent , which has not been predicted
by theory and may indicate the influence of long-range dipolar interactions
Epitaxial growth of deposited amorphous layer by laser annealing
We demonstrate that a single short pulse of laser irradiation of appropriate energy is capable of recrystallizing in open air an amorphous Si layer deposited on a (100) single-crystal substrate into an epitaxial layer. The laser pulse annealing technique is shown to overcome the interfacial oxide obstacle which usually leads to polycrystalline formation in normal thermal annealing
Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities
Dengue virus (DENV) is the leading mosquito-transmitted viral infection in the world. With more than 390 million new infections annually, and up to 1 million clinical cases with severe disease manifestations, there continues to be a need to develop new antiviral agents against dengue infection. In addition, there is no approved anti-DENV agents for treating DENV-infected patients. In the present study, we identified new compounds with anti-DENV replication activity by targeting viral replication enzymes – NS5, RNA-dependent RNA polymerase (RdRp) and NS3 protease, using cell-based reporter assay. Subsequently, we performed an enzyme-based assay to clarify the action of these compounds against DENV RdRp or NS3 protease activity. Moreover, these compounds exhibited anti-DENV activity in vivo in the ICR-suckling DENV-infected mouse model. Combination drug treatment exhibited a synergistic inhibition of DENV replication. These results describe novel prototypical small anti-DENV molecules for further development through compound modification and provide potential antivirals for treating DENV infection and DENV-related diseases
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