724 research outputs found
Lesbian and Gay
The time is past when librarians can assume no patron is lesbian or gay, or that there is no interest in gay research, Dan Tsang and Polly Thistlethwaite wrote in the introduction to the \u27Lesbian and Gay\u27 section of Katzes\u27 1989 edition of Magazines for Libraries. This title review of the queer periodicals of the day was intended to serve as a guide and justification for \u27mainstream\u27 libraries\u27 collection building. The number and range of titles in Thistlethwaite and Tsang\u27s collaborative entries (1989, 1992, and 1995) far exceeded any mainstream library collection known to either of the authors who were nevertheless hopeful that libraries would expand their gay, lesbian, bisexual, and transgender periodical holdings to better serve their communities. Lesbian and gay publications form the infrastructure of the communities. Tsang\u27s expertise about the \u27alternative press\u27 grew from his librarianship, his scholarship, his activism, journalism, and his extensive personal collecting; Thistlethwaite came to know the queer press by tending the periodical collection at the Lesbian Herstory Archives. The entry in this edition marked the AIDS epidemic\u27s influence on the rise of PWA literature; the emergence of periodicals by and for \u27lesbian and gay people of color\u27; and the proliferation of lesbian sex magazines
Research Data Management: Challenges and Opportunities
This talk addresses the next big challenge, data sharing of research data – not necessarily tied to journal publication. Addressing the international research landscape where funding agencies have begun to require research data management plans, the talk discusses what steps an academic institution can begin taking, the stakeholders who need to be at the table, the challenges faced, and the lessons learned thus far
Lesbian and Gay
The lesbian and gay press has shaped and reflected the rise of gay and lesbian liberation, Dan Tsang and Polly Thistlethwaite wrote in the introduction to the \u27Lesbian and Gay\u27 section of Katzes\u27 1992 edition of Magazines for Libraries. This title review of the queer periodicals of the day was intended to serve as a guide and justification for \u27mainstream\u27 libraries\u27 collection building. The number and range of titles in Thistlethwaite and Tsang\u27s collaborative entries (1989, 1992, and 1995) far exceeded any mainstream library collection known to either of the authors who were nevertheless hopeful that libraries would expand their gay, lesbian, bisexual, and transgender periodical holdings to better serve their communities. Tsang\u27s expertise about the \u27alternative press\u27 grew from his librarianship, his scholarship, his activism, journalism, and his extensive personal collecting; Thistlethwaite came to know the queer press by tending the periodical collection at the Lesbian Herstory Archives. The years of the AIDS epidemic also saw the proliferation of newsletters and journals from gay and lesbian people of color within the United States, especially African Americans and Asian Americans, we observed. Additionally, authors pressed the computerized indexing industry to include glbt titles in the indexes researchers used to find periodical articles
Lesbian, Gay, Bisexual, and Transgender
The proliferation of publications in the lesbian, Gay, bisexual, and transgender press has allowed the weaving of a well-informed network of previously isolated individuals and communities, empowering and unifying lesbian, gay, and other sexual minorities, Dan Tsang and Polly Thistlethwaite wrote in the introduction to the \u27Lesbian, Gay, Bisexual, and Transgender\u27 section of Katzes\u27 1995 edition of Magazines for Libraries. This title review of the queer periodicals of the day was intended to serve as a guide and justification for \u27mainstream\u27 libraries\u27 collection building. The number and range of titles in Thistlethwaite and Tsang\u27s collaborative entries (1989, 1992, and 1995) far exceeded any mainstream library collection known to either of the authors who were nevertheless hopeful that libraries would expand their gay, lesbian, bisexual, and transgender periodical holdings to better serve their communities. Lesbian and gay publications form the infrastructure of the communities. Tsang\u27s expertise about the \u27alternative press\u27 grew from his librarianship, his scholarship, his activism, journalism, and his extensive personal collecting; Thistlethwaite came to know the queer press by tending the periodical collection at the Lesbian Herstory Archives. The entry in this edition expanded its title to include Bisexual and Transgender. It also notes the ascendance of well-marketed gay \u27lifestyle\u27 publications, and the rise of small press zines and erotic magazines by people of color in counterpoint. The introductory essay mentions the advances in coverage for glbt periodicals by mainstream indexers as a result of activism and advocacy by the American Library Association\u27s Gay and Lesbian Task Force
Bounding biomass in the Fisher equation
The FKPP equation with a variable growth rate and advection by an
incompressible velocity field is considered as a model for plankton dispersed
by ocean currents. If the average growth rate is negative then the model has a
survival-extinction transition; the location of this transition in the
parameter space is constrained using variational arguments and delimited by
simulations. The statistical steady state reached when the system is in the
survival region of parameter space is characterized by integral constraints and
upper and lower bounds on the biomass and productivity that follow from
variational arguments and direct inequalities. In the limit of
zero-decorrelation time the velocity field is shown to act as Fickian diffusion
with an eddy diffusivity much larger than the molecular diffusivity and this
allows a one-dimensional model to predict the biomass, productivity and
extinction transitions. All results are illustrated with a simple growth and
stirring model.Comment: 32 Pages, 13 Figure
Surface reconstruction of pure-Cu single-crystal electrodes under Co-reduction potentials in alkaline solutions: A study by seriatim ECSTM-DEMS
Quasi-operando electrochemical scanning tunneling microscopy (ECSTM) recently showed that a polycrystalline Cu electrode kept in 0.1 M KOH at − 0.9 V (SHE), a potential very close to that for electrochemical CO reduction, underwent a two-step surface reconstruction, initially to Cu(111), or Cu(pc)-[Cu(111)], and terminally to Cu(100), or Cu(pc)-[Cu(100)]. When subjected to monolayer-limited Cu_((s)) ↔ Cu_2O_((s)) oxidation-reduction cycles (ORC), the Cu(pc)-[Cu(100)] surface was further transformed to Cu(pc)-[Cu(511)] that produced C_2H_5OH exclusively, as detected by differential electrochemical mass spectrometry, at an overvoltage lower by 645 mV relative to that for the formation of hydrocarbons. In this paper, results are presented from studies with the native monocrystalline surfaces Cu(111), Cu(100) and Cu(110). Whereas the intermediate Cu(pc)-[Cu(111)] layer was eventually converted to Cu(pc)-[Cu(100)], the surface of a pristine Cu(111) single crystal itself showed no such conversion. The surface of an original Cu(100) electrode likewise proved impervious to potential perturbations. In contrast, the outer plane of a Cu(110) crystal underwent three transformations: first to disordered Cu(110)-d[Cu(110)], then to disordered Cu(110)-d[Cu(111)], and finally to an ordered Cu(110)-[Cu(100)] plane. After multiple ORC, the converted [Cu(100)] lattice atop the Cu(110) crystal did not generate ethanol, in contrast to the [Cu(100)] phase above the Cu(pc) bulk. Quasi-operando ECSTM captured the disparity: Post-ORC, Cu(110)-[Cu(100)] was converted, not to Cu(110)-[Cu(511)], but to an ordered but catalytically inactive Cu(110)-[Cu(111)]; hence, no C2H5OH production upon reduction of CO, as would have been the case for a stepped Cu(511) surface
Withaferin A activates TRIM16 for its anti‐cancer activity in melanoma
Although selective BRAF inhibitors and novel immunotherapies have improved short-term treatment responses in metastatic melanoma patients, acquired resistance to these therapeutics still represent a major challenge in clinical practice. In this study, we evaluated the efficacy of Withaferin A (WFA), derived from the medicinal plant Withania Somnifera, as a novel therapeutic agent for the treatment of melanoma. WFA showed selective toxicity to melanoma cells compared to non-malignant cells. WFA induced apoptosis, significantly reduced cell proliferation and inhibited migration of melanoma cells. We identified that repression of the tumour suppressor TRIM16 diminished WFA cytotoxicity, suggesting that TRIM16 was in part responsible for the cytotoxic effects of WFA in melanoma cells. Together our data indicates that WFA has potent cytopathic effects on melanoma cells through TRIM16, suggesting a potential therapeutic application of WFA in the disease
Spin Foam Models of Riemannian Quantum Gravity
Using numerical calculations, we compare three versions of the Barrett-Crane
model of 4-dimensional Riemannian quantum gravity. In the version with face and
edge amplitudes as described by De Pietri, Freidel, Krasnov, and Rovelli, we
show the partition function diverges very rapidly for many triangulated
4-manifolds. In the version with modified face and edge amplitudes due to Perez
and Rovelli, we show the partition function converges so rapidly that the sum
is dominated by spin foams where all the spins labelling faces are zero except
for small, widely separated islands of higher spin. We also describe a new
version which appears to have a convergent partition function without drastic
spin-zero dominance. Finally, after a general discussion of how to extract
physics from spin foam models, we discuss the implications of convergence or
divergence of the partition function for other aspects of a spin foam model.Comment: 23 pages LaTeX; this version to appear in Classical and Quantum
Gravit
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