Doctor of Philosophy

dissertationThe behavior of foam films is significant in many areas such as mineral flotation, food processing, and oil recovery. The film stability between two bubbles in foams has been motivated by different research interests. This dissertation contributes to the understanding of the film stability based on several methods of evaluation. First, the structure of thin water films during the rupture process was investigated by a new approach, which combines molecular dynamics simulation (MDS) with image processing analysis. The procedure was developed to convert the MDS trajectories to readable 3D images. The films were studied at different thicknesses by MDS to determine the critical thickness at which film ruptures. The potential energy of each thickness during simulation time was analyzed. A new procedure involving the calculation of molecular porosity was developed. Results indicate a critical molecular porosity value of 49% for film rupture. Second, disjoining pressure (DP) in thin films was examined by using Matlab. The surface charge regulation approach was applied to develop a new model for computing of DP. The case of sodium dodecyl sulfate (SDS) adsorption from NaCl solution was studied. A model of film drainage rate was developed accordingly which showed a good agreement with experimental data from the literature. Finally, features of interfacial water at air-water interfaces of anionic SDS and cationic dodecyl amine hydrochloride (DDA) solutions were examined by combining sum frequency generation (SFG) vibrational spectroscopy measurements and MDS. The SFG spectra and MDS results revealed that interfacial waters for SDS solutions was highly-ordered compared with those for DDA solutions. SFG results revealed that interfacial waters at pH 9 in both SDS and DDA solutions showed less-ordered than at pH 7. Experiments on foam stability and foam weight were conducted under the same conditions. Results revealed that for SDS solutions, foams were more stable at pH 7 than at pH 9. The opposite was observed for DDA solutions, in which case stability decreased when pH increased. Results were explained based on the extent of surfactant hydration at interfaces which is thought to account for film stability as revealed from results on foam stability

Efficient Finetuning Large Language Models For Vietnamese Chatbot

Large language models (LLMs), such as GPT-4, PaLM, and LLaMa, have been shown to achieve remarkable performance across a variety of natural language tasks. Recent advancements in instruction tuning bring LLMs with ability in following user's instructions and producing human-like responses. However, the high costs associated with training and implementing LLMs pose challenges to academic research. Furthermore, the availability of pretrained LLMs and instruction-tune datasets for Vietnamese language is limited. To tackle these concerns, we leverage large-scale instruction-following datasets from open-source projects, namely Alpaca, GPT4All, and Chat-Doctor, which cover general domain and specific medical domain. To the best of our knowledge, these are the first instructional dataset for Vietnamese. Subsequently, we utilize parameter-efficient tuning through Low-Rank Adaptation (LoRA) on two open LLMs: Bloomz (Multilingual) and GPTJ-6B (Vietnamese), resulting four models: Bloomz-Chat, Bloomz-Doctor, GPTJ-Chat, GPTJ-Doctor.Finally, we assess the effectiveness of our methodology on a per-sample basis, taking into consideration the helpfulness, relevance, accuracy, level of detail in their responses. This evaluation process entails the utilization of GPT-4 as an automated scoring mechanism. Despite utilizing a low-cost setup, our method demonstrates about 20-30\% improvement over the original models in our evaluation tasks.Comment: arXiv admin note: text overlap with arXiv:2304.08177, arXiv:2303.16199 by other author

New records and morphological assessments of long-nosed fruit bats (chiroptera: pteropodidae: Macroglossus spp.) from Vietnam

Long-nosed fruit bat is a common name of the genus Macroglossus which comprises two species: Dagger-toothed long-nosed fruit bat (M. minimus) and Greater long-nosed fruit bat (M. sobrinus). These two species were rarely recorded from Vietnam or neighboring countries. Within Vietnam, M. minimus has been recorded only from two localities in southern Vietnam while M. sobrinus was known from all northern, central and southern regions of the country. Morphological features of these species in Vietnam were poorly documented in previous publications. With results from a rapid examination of all specimens and recently captured individuals, we here confirm that M. sobrinus is distinctively larger than M. minimus in all external and craniodental measurements. Two species are also distinguishable by their nostril shapes and mandible symphyses. This paper provides new distributional records of both M. sobrinus and M. minimus from Vietnam with remarks on their ecology and habitats.

Attitudes toward Self-Disclosure on Facebook: A Review of Perception, Emotion and Behavior in University Students

A number of social networking platforms have emerged as a result of the development of information and communication technology which have become increasingly user-friendly and full with valuable features. The social networking site with most users is Facebook. Teenagers, particularly college students use Facebook most frequently to study, gain information, entertain themselves and connect with others through self-disclosing personal information on the Facebook profile page. This quantitative study aimed to analyze the attitude of pedagogical students regarding self-disclosure on Facebook as represented through cognition, emotion and behavior concerning academic achievement. The survey was completed by 535university student’s majority in pedagogy. There were 41 students who used it for less than three years between three to five years by 218 students and 276 students who use it more than five years. The questionnaire was self-reported by participants to assess university students' attitudes toward self-disclosure on Facebook. The results indicate that pedagogical students with excellent academic achievement and more than five years of Facebook experience had the highest-level attitude toward self-disclosure on Facebook. The results indicate a positive relationship between cognition, emotion and influence factors students' Facebook attitudes. Future research on methods that enhance student positive disclosure can benefit from this study. Future research should examine how self-disclosure on Facebook relates to other aspects, such as Facebook usage time, financial state and perception of advantages and its disadvantages of Facebook in order to evaluate students' attitudes objectively

First record of Cantharellus minor from Vietnam with identification support from a combination of nrLSU and nrSSU phylogenetic analysis

Background: A previously identified sample XC02, which was collected from a pine forest (Pinus kesiya Royle ex Gordon), in Xuan Tho Commune, Da Lat, Lam Dong Province, Vietnam, was identified as Cantharellus minor based on morphology and nrLSU phylogeny analysis. Sequence analysis of multiple genes are becoming more and more common for phylogenetic analysis of mushrooms.Method: Total DNA was isolated from sample XC02. The primer NS1, NS4 were applied to amplify the target gene the nuclear ribosomal small subunit DNA (nrSSU). For phylogenetic analysis, individual and concatenated datasets (nrSSU and nrLSU-nrSSU) were constructed. Phylogenetic tree was constructed with MEGA 6.0 with a 1000 replicate bootstrap based on the neighbor joining, maximum likelihood, maximum parsimony method.  Results: A concatenated dataset containing a total of 14 sequences from Cantharellus, Craterellus (Cantharellaceae, Canthraellales) and Hydnum (Hydnaceae, Cantharellales) were constructed. For the specimen XC02, the phylogenies based on the first, second, and third datasets (nrLSU, nrSSU, and nrLSU-nrSSU) and the morphological analysis, reported in our previous study, strongly confirmed the identity of XC02 as Cantharellus minor.Conclusion: The combination between the morphological analysis and phylogenetic analysis is confirmed as the best approach for the identification of Cantharellus and other mushroom species that we collected in the Central Highlands, Vietnam.Keywords: nrLSU; Cantharellus, Cantharellus minor; nrSSU; nrLSU; phylogeny analysis; Vietna

MUTATION ANALYSIS OF DJ-1 GENE IN VIETNAMESE PARKINSON’S DISEASE PATIENTS

Parkinson’s disease (PD) is a degenerative condition of the brain of uncertain cause that mainly affects older people. Shaking is a distinctive feature of the disease, but slowness, poverty of movement and stiffness interfere with everyday life. A large number of known pathogenic mutations of genes related to PD have been identified. The DJ-1 gene, one of PARK genes, is considered as the primary cause of PD in different populations. The analysis of mutation frequency of the DJ-1 gene in Vietnamese PD patients is necessary to clarify the pathogenic associations of PD with the DJ-1 gene and to understand the pathogenesis and genetic mechanisms of PD. In this study, genomic DNA was extracted from peripheral blood of 30 PD patients (mean age 64.11 ± 7.31 years) and 20 controls and directed Sanger sequencing of one fragment of DJ-1 gene, containing the introns 4 and 5 as well as exon 5. The obtained results showed that there were 13 heterozygous or homozygous point mutations in introns 4 and 5. The late-onset sporadic PD (LOPD) patient carried a single homozygous mutation in intron 5 (IVS5+31GA), and others had a heterozygous mutation, all of unknown significance.  Moreover, both the Ala86Glu and Gly95Leu mutations in exon 5 were present in one LOPD patient suggesting possible change of functional protein. Analysis of these mutations were shown the nonsynonymous and uncertain significant mutation, therefore they may not be related to pathogenic mutations of PD. Further research is needed to study the contribution of the novel found mutation in other PARK genes to the pathogenesis of Vietnamese PD patients

ĐẶC ĐIỂM DÒNG CHẢY VEN BỜ BẮC TRUNG BỘ (HÀ TĨNH - THỪA THIÊN-HUẾ) THỜI KỲ 4/2016

This paper presents the modeled results of general current pattern (daily average value) in Northern Central Vietnam Coast (Ha Tinh - Thua Thien-Hue) during April 2016. Study results show that in general, current flowed from the North to the South with small and instable velocity (V ≈ 0.1 - 0.2 m/s). From 2nd to 6th April current flowed from the South to the North. From 7th to 29th April current flowed from the North to the South. During 13rd to 16th April current velocity was weak (V ≤ 0.1 m/s). In the southern region of Thua Thien-Hue province, the direction of current was instable (from 6th to 9th and from 20th to 22nd April current flowed from the South to the North). Current distribution pattern from modeled results was in accordance with the propagation characteristics of surface water temperatures in the studied area through data analysis of satellite images.Bài báo trình bày kết quả tính toán trường dòng chảy tổng hợp trung bình ngày cho khu vực ven bờ Bắc Trung Bộ (Hà Tĩnh - Thừa Thiên-Huế) thời kỳ 4/2016. Kết quả nghiên cứu cho thấy trong thời gian nghiên cứu nhìn chung dòng chảy tổng hợp trung bình ngày có hướng từ bắc xuống nam, tốc độ tương đối nhỏ V ≈ 0,1 - 0,2 m/s và không ổn định. Từ 2-6/4/2016 dòng chảy tổng hợp trung bình ngày ven bờ có hướng từ nam lên bắc. Từ 7-29/4/2016 dòng chảy ven bờ có hướng từ bắc xuống nam. Các ngày 13-16/4/2016 dòng chảy tổng hợp trung bình ngày có tốc độ nhỏ (V ≤ 0,1 m/s). Khu vực phía nam Thừa Thiên-Huế dòng chảy tổng hợp trung bình ngày có hướng bị biến động mạnh nhất (các ngày 6-9/4 và 20-22/4 hướng dòng từ nam lên bắc). Đặc điểm phân bố dòng chảy tính toán tương đối phù hợp với đặc điểm lan truyền nhiệt độ nước tầng mặt tại khu vực nghiên cứu qua số liệu phân tích ảnh vệ tinh

Geographic isolation created distinct pelage characters in Finlayson’s squirrel on isolated island offshore of the Indochina Peninsula in Central Vietnam

We found distinct pelage characters in Finlayson’s squirrel (Callosciurus finlaysonii) population, which is endemic to Lao Island of the Cham Islands, located off the coast of central Vietnam. Among squirrels of the ‘C. erythraeus-finlaysonii complex’, which consists of all forms of C. erythraeus and C. finlaysonii, mitochondrial cytochrome-b sequences show that the Lao Island squirrel forms a cluster with C. finlaysonii with external characters of C. erythraeus flavimanus, defined previously as ‘C. finlaysonii morpha flavimanus’. Both squirrel forms, however, differed in pelage colour. This different colouration may have arisen from the effect of geographic isolation

Factors Influence on Promotion Mix in E-marketing: Case of Technology Services Enterprise in Vietnam

Purpose: The objective of this study is to clarify factors affecting the promotion mix in E-Marketing, with specific target audience being enterprises operating in the technology service industry in Vietnam.   Theoretical framework: Based on the promotion theory and social exchange theory, this study focuses on the factors that influence on the promotion decision in firms.   Design/Methodology/Approach: This study applies both qualitative and quantitative methods with data collected from a questionnaire survey.   Findings: There are 4 factors respectively Sales Promotion, Advertising, Public Relations and Personal Selling that affect the mixed promotion activities in E-Marketing of technology service enterprises in Vietnam.   Research, practical & social implications: This study propose solutions to improve the promotion activities in the e – marketing of firms in Vietnam.   Originality/Value: This study is one of the early studies that have focused in this field in Vietnam.Propósito: El objetivo de este estudio es aclarar los factores que afectan la combinación de promoción en E-Marketing, con un público objetivo específico que son las empresas que operan en la industria de servicios de tecnología en Vietnam. Marco teórico: Basado en la teoría de la promoción y la teoría del intercambio social, este estudio se centra en los factores que influyen en la decisión de promoción en las empresas. Diseño/metodología/enfoque: este estudio aplica métodos cualitativos y cuantitativos con datos recopilados de una encuesta de cuestionario. Hallazgos: Existen 4 factores, respectivamente, Promoción de Ventas, Publicidad, Relaciones Públicas y Ventas Personales que afectan las actividades mixtas de promoción en E-Marketing de las empresas de servicios de tecnología en Vietnam. Implicaciones de investigación, prácticas y sociales: este estudio propone soluciones para mejorar las actividades de promoción en el marketing electrónico de las empresas en Vietnam. Originalidad/valor: Este estudio es uno de los primeros que se han centrado en este campo en Vietnam.Objetivo: O objetivo deste estudo é esclarecer os fatores que afetam o mix de promoção no E-Marketing, tendo como público-alvo específico as empresas que operam no setor de serviços de tecnologia no Vietnã.. Referencial teórico: Com base na teoria da promoção e na teoria das trocas sociais, este estudo se concentra nos fatores que influenciam a decisão de promoção nas empresas.. Desenho/metodologia/abordagem: Este estudo aplica métodos qualitativos e quantitativos com dados coletados de uma pesquisa por questionário. Resultados: Existem 4 fatores, respectivamente, Promoção de Vendas, Publicidade, Relações Públicas e Vendas Pessoais que afetam as atividades de promoção mista em E-Marketing de empresas de serviços de tecnologia no Vietnã. Pesquisa, implicações práticas e sociais: Este estudo propõe soluções para melhorar as atividades de promoção no e – marketing de empresas no Vietnã. Originalidade/valor: Este estudo é um dos primeiros estudos que se concentraram neste campo no Vietnã. Palavras-chave:  Mix de promoção; E-Marketing; Serviços de tecnologia; Vietn