627 research outputs found
A ray mode parabolic equation for shallow water acoustics propagation problems
Ray mode parabolic equations which are suitable for shallow water acoustics
propagation problems are derived by the multiple-scale method.Comment: 7 pp., 0 fi
A nonstationary form of the range refraction parabolic equation and its application as an artificial boundary condition for the wave equation in a waveguide
The time-dependent form of Tappert's range refraction parabolic equation is
derived using Daletskiy-Krein formula form noncommutative analysis and proposed
as an artificial boundary condition for the wave equation in a waveguide. The
numerical comparison with Higdon's absorbing boundary conditions shows
sufficiently good quality of the new boundary condition at low computational
cost.Comment: 12 pages, 9 figure
Molecular-genetic aspects of the endometrium state on the day of the tentative implantation window in women with recurrent miscarriage in the programs of assisted reproductive technologies
Golovatyuk K. P., Nosenko O. M., Makshayeva E. T., Trofimov D. Yu., Donnikov A. E., Kolin V. V. Molecular-genetic aspects of the endometrium state on the day of the tentative implantation window in women with recurrent miscarriage in the programs of assisted reproductive technologies. Journal of Education, Health and Sport. 2017;7(9):621-626. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1068361
http://ojs.ukw.edu.pl/index.php/johs/article/view/5076
The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017).
1223 Journal of Education, Health and Sport eISSN 2391-8306 7
© The Authors 2017;
This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,
provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License
(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 15.08.2017. Revised: 20.09.2017. Accepted: 29.09.2017.
MOLECULAR-GENETIC ASPECTS OF THE ENDOMETRIUM STATE ON THE DAY OF THE tentative IMPLANTATION WINDOW IN WOMEN WITH recurrent miscarriage IN THE PROGRAMS OF ASSISTED REPRODUCTIVE TECHNOLOGIES
1K. P. Golovatyuk, 2O. M. Nosenko, 1E. T. Makshayeva, 3D. Yu. Trofimov,
4A. E. Donnikov, 3V. V. Kolin
1Limited Liability Company Medical Center for Reproductive Health "Gameta", Odessa, Ukraine;
2Odessa National Medical University, Ukraine;
3Limited Liability Company "NPF DNA-Technology", Moscow, Russia;
4FGBU Scientific Center for Obstetrics, Gynecology and Perinatology.
named after acad. V.I. Kulakov Ministry of Health care and Social Development of Russia, Moscow, Russia;
e-mail: [email protected]
Abstract
More than 50% of pregnant women after the programs of assisted reproductive technologies (ART) face the problem of recurrent miscarriage (RMC), especially in the first trimester. Significant role in the development of RMC has infectious factor and chronic inflammation in the endometrium. The aim: to reveal the peculiarities of immune response mRNA genes of the inflammatory component expression in the period of the tentative implantation window (TIW) in women with RMC in ART programs. Material and methods. The main group consisted of 240 patients with RMC in ART programs; the control group included 100 conditionally healthy fertile women. On the ground of PCR reverse transcription, the mRNA of the IL-1β, IL-2, IL-10, Foxp3, TLR9, IL-2Rα cytokine genes was examined in endometrial samples obtained with the help of biopsy on the TIW day. Results. Analysis of the transcriptional profile of the immune response genes in the endometrium on TIW day revealed that the relative level of mRNA expression of the IL-1β, IL-2, Foxp3, TLR9, IL-2Rα genes did not differ significantly in the main and control groups. Statistically significant decrease in mRNA expression of IL-10 gene was observed in women with RPL. Conclusions. A feature of mRNA expression of the inflammatory component of the immune response in TIW period in women with RMC in ART programs is a decrease in the expression level of the IL-10 gene mRNA, which may be one of the reasons for the unfavorable outcomes of the onset pregnancy.
Key words: recurrent miscarriage, assisted reproductive technologies, immune response, reverse transcription-polymerase chain reaction, tentative implantation window
Sensitivities of Low Energy Reactor Neutrino Experiments
The low energy part of the reactor neutrino spectra has not been
experimentally measured. Its uncertainties limit the sensitivities in certain
reactor neutrino experiments. The origin of these uncertainties are discussed,
and the effects on measurements of neutrino interactions with electrons and
nuclei are studied. Comparisons are made with existing results. In particular,
the discrepancies between previous measurements with Standard Model
expectations can be explained by an under-estimation of the low energy reactor
neutrino spectra. To optimize the experimental sensitivities, measurements for
\nuebar-e cross-sections should focus on events with large (1.5 MeV)
recoil energy while those for neutrino magnetic moment searches should be based
on events 100 keV. The merits and attainable accuracies for
neutrino-electron scattering experiments using artificial neutrino sources are
discussed.Comment: 25 pages, 9 figure
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