Contemporary Trends of Information Seeking Behaviour of Research Scholars of Gujarat University: A Case study

The study inspects the Information needs and seeking behavior of research scholars of Gujarat University in Social science and Linguistics disciplines. Sample constituted the population of total 80 research scholars from social science and linguistic disciplines. The study conducted through survey methodology with questionnaire developed basis on the core compounds of information seeking behaviour and collected the research data from the registered research scholars of Gujarat University. The results revealed that female little dominated in research work and the major purpose of seeking behaviour is for research work, knowledge enrichment and writing research and conference papers. Research scholars desired to use Gujarat university central library and their department library to pursue information. Study shows that research scholars have initiated to use various e-resources and internet based services but still they are not aware about remote login and File Transfer Protocol (FTP). Majority of research scholar’s consults print resources mainly reference collection, subject books and periodicals followed by digital resources for their on-going research work. Research scholars desired to discuss with subject experts and participates workshops and conferences on their areas for updating with current trends. Study also explored the difficulty faced by the scholars in information seeking activities. Study found that majority of scholars reported problem to access e-resources of university library and due to the information overload facing difficulty to identify appropriated sources. Study concluded with the recommendations to the university library authority to understand the research scholar’s needs and reframe the library management system based on the social scientists requirement and provide batter quality library services to this important community

Application of Cloud Computing in University Libraries: Case Study of Selected University Libraries in Gujarat

The purpose of this paper is to determine the awareness and use of cloud computing services and technology among library personnel and library users in selected university libraries in Gujarat, India. A detailed survey was piloted using structured set of questionnaires among 210 library users which comprised of post graduate students, research scholars and faculty of the respective university and 15 senior library professionals participated in the survey. Study discovered that 78.57% of library users and 80% of library staff are aware about cloud technology. They are using multiple devices for cloud computing and 65.71% of library users using Laptop and 31.41% of them using smart phone, tablets and ipads. Majority of professional library staff use desktop and expressed that cloud technology is very useful in providing library services. Maximum 96% of respondents using Gmail services, 52.44% video service through YouTube, 65.78% using Google drive for file storage & sharing services. It is observed that library personnel used less of event calendar and online presentation. They are using cloud technology for acquisition and technical work data import and export purpose. 73.33% of library staff expressed that library services is improved by using cloud technology and overall 66.67% of them are satisfied with application of existing cloud technology in university library. It is also perceived that majority of library professionals stated that basic training is required to use advanced cloud technology in university library. Study concluded with the recommendations to enhance library services with maximum utilization of available cloud technology in university library

Prevalence of Risk Factors of Non-communicable Diseases in a District of Gujarat, India

The study attempted to identify the prevalence and distribution of risk factors of non-communicable diseases among urban and rural population in Gujarat, India. Using the WHO stepwise approach, a crosssectional study was carried out among 1,805 urban and 1,684 rural people of 15-64 years age-group. Information on behavioural and physiological risk factors of non-communicable diseases was obtained through standardized protocol. High prevalence of smoking (22.8%) and the use of smokeless tobacco (43.4%) were observed among rural men compared to urban men (smoking-12.8% and smokeless tobacco consumption-23.1%). There was a significant difference in the average consumption of fruits and vegetables between urban (2.18\ub11.59 servings) and rural (1.78\ub11.48 servings) area. Prevalence of overweight and obesity was observed to be high among urban men and women in all age-groups compared to rural men and women. Prevalence of behavioural risk factors, overweight, and obesity increased with age in both the areas. Twenty-nine percent of the urban residents and 15.4% of the rural residents were found to have raised blood pressure, and the difference was found to be statistically significant (p<0.01). For both men and women, the prevalence of overweight and obesity, hypertension, and lack of physical activities were significantly higher in the urban population while smoking, smokeless tobacco consumption, poor consumption of fruits and vegetables were more prevalent in the rural population. The results highlight the need for interventions and approaches for the prevention of risk factors of non-communicable diseases in rural and urban areas

EPIDEMIC INVESTIGATION OF AN ACUTE GASTROENTERITIS OUTBREAK IN DASLANA VILLAGE OF AHMEDABAD, GUJARAT

Background: Diarrhoeal diseases affect millions of people around the world and have greatest impact on children, especially those in developing countries. Diarrhoeal disease outbreaks are cause of major public health emergencies in India. We investigated such an outbreak of acute gastroenteritis in Daslana Village of Ahmedabad district, Gujarat, to identify etiological agent, source of transmission and propose control measures. Methodology: A cross sectional epidemiological study was carried out to find out the cases of acute gastroenteritis by house to house survey, and also inspected the sanitation and water supply. Results: There were 38 cases of acute gastroenteritis among total 220 peoples who were residing near brick production sites, overall attack rate was 17.27%. Infants and children of 1 to 12 years of age were highly affected, (25%) and (20.56%) respectively. Conclusion: The underlying cause for this outbreak of acute gastroenteritis was waterborne in nature and due to contamination of water with contributing factors of poor living condition

A randomized, double-blind, duloxetine-referenced study comparing efficacy and tolerability of 2 fixed doses of vortioxetine in the acute treatment of adults with MDD

RATIONALE: Vortioxetine has reduced depressive symptoms in adults with major depressive disorder (MDD) in multiple clinical trials. OBJECTIVES: The aim of this study is to evaluate the efficacy, safety, and tolerability of vortioxetine 15 and 20 mg vs placebo in adults with MDD. METHODS: Patients were randomized 1:1:1:1 to vortioxetine 15 mg, vortioxetine 20 mg, duloxetine 60 mg (active reference), or placebo. The primary efficacy endpoint was mean change in Montgomery–Åsberg Depression Rating Scale (MADRS) total score at week 8 (MMRM). Safety/tolerability assessments included physical examinations, vital signs, laboratory evaluations, electrocardiograms, adverse events (AEs), Columbia–Suicide Severity Rating Scale, Arizona Sexual Experiences Scale, and Discontinuation–Emergent Signs and Symptoms checklist. RESULTS: Six hundred and fourteen patients were randomized. Mean changes in MADRS scores were −12.83 (±0.834), −14.30 (±0.890), −15.57 (±0.880), and −16.90 (±0.884) for placebo, vortioxetine 15 mg (P = .224), vortioxetine 20 mg (P = .023), and duloxetine 60 mg (P < .001) (P vs placebo), respectively. AEs reported by ≥5 % of vortioxetine patients included nausea, headache, diarrhea, dizziness, dry mouth, constipation, vomiting, insomnia, fatigue, and upper respiratory infection. Treatment-emergent sexual dysfunction, suicidal ideation or behavior, and discontinuation symptoms were not significantly different between vortioxetine and placebo. CONCLUSIONS: Vortioxetine 20 mg significantly reduced MADRS total scores after 8 weeks of treatment. Both vortioxetine doses were well tolerated. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov identifier NCT01153009; www.clinicaltrials.gov/

Concurrent variations of median and musculocutaneous nerves and their clinical correlation – a cadaveric study

Variations of median nerve, musculocutaneous nerve and their communicating branches are of interest for anatomists and surgeons. These variations may be vulnerable to damage in surgical procedures. We examined median nerve and musculocutaneous nerve concurrently in 58 cadavers, i.e. 116 superior extremities, and found median nerve innervating muscle of the anterior compartment of arm in the absence of musculocutaneous nerve in 11.2% superior extremities, splitting of median nerve in the arm into median nerve proper and musculocutaneous nerve in 5.12% superior extremities, and communication between median and musculocutaneous nerves in 20.7% superior extremities. Knowledge of such anatomical variations is helpful for surgeons treating neoplasm or repairing trauma

Global research trends of interleukin-6 in SARS-CoV-2 infection

528-535IL-6 levels are significantly elevated in COVID-19 patients and are associated with poor clinical outcomes. Inhibiting IL-6 is thought to be a unique therapeutic strategy for the control of dysregulated host responses in SARS-CoV-2. The present study focuses on evaluating the research productivity of IL-6 level in SARS-CoV-2 infection using various bibliometric indicators and analysed 4510 research papers related to IL-6 levels in SARS-CoV-2 from the Scopus database and VOS Viewer tool applied for visualization. The results revealed that ascendant trends in the publications and USA, China and Italy have secured top three position in numbers of publications. Study observed that “Dagna L.” received top prolific author rank. Article entitled “Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China” received maximum of 15364 total citations, whereas “Frontiers in Immunology” and “Journal of Medical Virology” secured in top two highly productive journals in the subject with extreme link strength. With regard to organisation, “Tongji Medical College-China” reported highly dynamic organization. “COVID-19”; “SARS-CoV-2”; “Interleukin” received maximum occurrences with high link strength. In view of global mounting public health issue of COVID-19, primarily due to increased viral transmissibility and associated cytokine storm, the present study will helpful for the medical professionals to know the research trends and also library authority for updating collection development policy in the specific subject domains

Early Ultrasound Surveillance of Newly-Created Hemodialysis Arteriovenous Fistula

Introduction: We assess if ultrasound surveillance of newly-created arteriovenous fistulas (AVFs) can predict nonmaturation sufficiently reliably to justify randomised controlled trial (RCT) evaluation of ultrasounddirected salvage intervention. Methods: Consenting adults underwent blinded fortnightly ultrasound scanning of their AVF after creation, with scan characteristics that predicted AVF non-maturation identified by logistic regression modelling. Results: Of 333 AVFs created, 65.8% matured by 10 weeks. Serial scanning revealed that maturation occurred rapidly, whereas consistently lower fistula flow rates and venous diameters were observed in those that did not mature. Wrist and elbow AVF non-maturation could be optimally modelled from the week four ultrasound parameters alone, but with only moderate positive predictive values (wrist, 60.6% (95% CI 43.9 – 77.3); elbow, 66.7% (48.9 - 84.4)). Moreover, 40 (70.2%) of the 57 AVFs that thrombosed by week 10 had already failed by the week 4 scan, thus limiting the potential of salvage procedures initiated by that scan’s findings to alter overall maturation rates. Modelling of the early ultrasound characteristics could also predict primary patency failure at 6 months, but that model performed poorly at predicting assisted primary failure (those AVFs that failed despite a salvage attempt), partly because patency of at-risk AVFs was maintained by successful salvage performed without recourse to the early scan data. Conclusions: Early ultrasound surveillance may predict fistula maturation, but is likely, at best, to result in only very modest improvements in fistula patency. Power calculations suggest that an impractically large number of participants (>1700) would be required for formal RCT evaluation

Baseline assessment of evidence-based intrapartum care practices in medical schools in 3 states in India: a mixed-methods study

Introduction: Implementation research with pre- and post-comparison was planned to improve the quality of evidence-based intrapartum care services in Indian medical schools. We present the baseline study results to assess the status of adherence to intrapartum evidence-based practices (IP-EBP) in study schools in 3 states in India and the perception of the faculty. Methods: A concurrent mixed-methods approach was used to conduct the baseline assessment in 9 medical schools in Rajasthan, Gujarat, and Union Territory from October 2018 to June 2019. IP-EBP among pregnant women in uncomplicated first (n=135), second (n=120), and third stage (n=120) of labor were observed using a predesigned, pretested checklist quantitatively. We conducted in-depth interviews with 33 obstetrics and gynecology faculty to understand their perceptions of intrapartum practices. Quantitative data were analyzed using SPSS (version 22). COM-B (Capability, Opportunity, and Motivation Behavior) model was used to understand the behaviors, and thematic analysis was done for the qualitative data. Findings: Unindicated augmentation of labor was done in 64.4%, fundal pressure applied in 50.8%, episiotomy done in 58.3%, and delivery in lithotomy position was performed in 86.7% of women in labor. Conclusions: Intrapartum practices that are not recommended were routinely practiced in the study medical schools due to a lack of staff awareness of evidence-based practices and incorrect beliefs about their impact