Stroke Symbol Generation Software for Fighter Aircraft

This paper gives an overview of the stroke symbol generation software developed by Hindustan Aeronautics Limited for fighter aircraft. This paper covers the working principle of head-up-display, overview of target hardware on which the developed software has been integrated and tested, software architecture, hardware software interfaces and design details of stroke symbol generation software. The paper also covers the issues related to stroke symbol quality which were encountered by the design team and the details about how the issues were resolved during integration and test phase.Defence Science Journal, 2013, 63(2), pp.153-156, DOI:http://dx.doi.org/10.14429/dsj.63.425

Induced cytomictic diversity in maize (Zea mays L.) inbred

Mutation breeding has been used for improving oligogenic and polygenic characters, disease resistance and quantitative characters including yielding ability. The cytological stability of maize inbred lines is an important consideration in view of their extensive use in genetics and plant breeding research. Investigation in Zea mays L. confirms that the migration of chromosomes is a real event that cannot be misunderstood as an artifact produced by fixation or mechanical injuries.Мутационная селекция используется для улучшения моногенных и полигенных признаков, устойчивости к заболеваниям и количественных характеристик, включая урожайность. Цитологическая стабильность инбредных линий кукурузы важна с точки зрения их широкого использования в генетике и селекции. Исследования, проведенные на кукурузе, подтверждают, что миграция хромосом является реальным событием, которое не может быть неправильно понято как артефакт, полученный в результате фиксации или механических повреждений.Мутаційна селекція використовується для поліпшення моногенних та полігенних ознак, стійкості до захворювань і кількісних характеристик, включаючи врожайність. Цитогенетична стабільність інбредних ліній кукурудзи важлива з точки зору їх широкого використання в генетиці та селекції. Дослідження, проведені на кукурудзі, підтверджують, що міграція хромосом є реальною подією, котра не може бути неправильно зрозумілою як артефакт, який отримали в результаті фіксації чи механічних пошкоджень

An Innovative Approach for the Detection of High Boiler Adulterants in Sandalwood and Cedarwood Essential Oils

866-874Owing to the important uses of essential oils, its adulteration is a serious issue of concern. Among the adulterants, the high volatiles can be detected through GC and GC/MS. However, the detection of subtle high boiler adulterants is extremely difficult, and requires development of novel techniques to overcome the challenges faced by the essential oil industry. In current study, the thermogravimetric analysis (TGA) was validated as an innovative approach for quantitative estimation of adulteration in essential oils taking sandalwood and cedarwood oils as case study. The low−cost vegetable oils like castor oil, coconut oil, and synthetic polymer like polyethylene glycol-400 (PEG-400) were used as high boiler adulterants. The physical parameters like specific gravity and refractive index of pure and adulterated oil samples were analyzed followed by their TGA analysis. The physical parameters of adulterated samples did not show significant variation from that of pure essential oils, thus need alternate analytical techniques to overcome this issue. The TGA of pure essential oil was volatized in single−stage around 200–260℃, whereas the high boiler adulterants such as vegetable oils and synthetic PEG-400 majorly volatized in the range 300–500℃ and 260–400℃, respectively. The adulterated samples exhibited mostly two-stage weight loss pattern, which was quantitatively estimated with high accuracy by this technique. Therefore, the TGA analysis can be used as a novel technique for rapid and precise detection of high boiler adulterants in essential oils like sandalwood and cedarwood due to difference in their volatile behaviour

An Innovative Approach for the Detection of High Boiler Adulterants in Sandalwood and Cedarwood Essential Oils

Owing to the important uses of essential oils, its adulteration is a serious issue of concern. Among the adulterants, the high volatiles can be detected through GC and GC/MS. However, the detection of subtle high boiler adulterants is extremely difficult, and requires development of novel techniques to overcome the challenges faced by the essential oil industry. In current study, the thermogravimetric analysis (TGA) was validated as an innovative approach for quantitative estimation of adulteration in essential oils taking sandalwood and cedarwood oils as case study. The low−cost vegetable oils like castor oil, coconut oil, and synthetic polymer like polyethylene glycol-400 (PEG-400) were used as high boiler adulterants. The physical parameters like specific gravity and refractive index of pure and adulterated oil samples were analyzed followed by their TGA analysis. The physical parameters of adulterated samples did not show significant variation from that of pure essential oils, thus need alternate analytical techniques to overcome this issue. The TGA of pure essential oil was volatized in single−stage around 200–260℃, whereas the high boiler adulterants such as vegetable oils and synthetic PEG-400 majorly volatized in the range 300–500℃ and 260–400℃, respectively. The adulterated samples exhibited mostly two-stage weight loss pattern, which was quantitatively estimated with high accuracy by this technique. Therefore, the TGA analysis can be used as a novel technique for rapid and precise detection of high boiler adulterants in essential oils like sandalwood and cedarwood due to difference in their volatile behaviour

Novel Coronavirus: A Newly Arranged Mini-Review

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was originally known as a virus that infects animals and rarely can be transmitted to humans in large populations, is now transformed into one of the most feared pandemics causes worldwide. Infection by a virus that is officially known as COVID-19 has caused global concern mainly due to the number of deaths caused. Since it was first reported in Wuhan, China in December 2019, now COVID-19 has spread to almost all parts of the world with a very rapid spread rate. The main symptom of this infection is a respiratory disease accompanied by other symptoms that resemble flu-like illness. Everyone can suffer from COVID-19, but the elderly, toddlers, pregnant women, and people with certain diseases and disorders of the immune system show more severe symptoms. The disease is transmitted through inhalation or contact with droplets, where the incubation period ranges from 2 to 14 days. Until now, specific therapy to treat COVID-19 has not been found, with preventive measures taken to control its spread. In this mini-review, we will explain important information related to COVID-19

Leishmania donovani triose phosphate isomerase: a potential vaccine target against visceral leishmaniasis

Visceral leishmaniasis (VL) is one of the most important parasitic diseases with approximately 350 million people at risk. Due to the non availability of an ideal drug, development of a safe, effective, and affordable vaccine could be a solution for control and prevention of this disease. In this study, a potential Th1 stimulatory protein- Triose phosphate isomerase (TPI), a glycolytic enzyme, identified through proteomics from a fraction of Leishmania donovani soluble antigen ranging from 89.9–97.1 kDa, was assessed for its potential as a suitable vaccine candidate. The protein- L. donovani TPI (LdTPI) was cloned, expressed and purified which exhibited the homology of 99% with L. infantum TPI. The rLdTPI was further evaluated for its immunogenicity by lymphoproliferative response (LTT), nitric oxide (NO) production and estimation of cytokines in cured Leishmania patients/hamster. It elicited strong LTT response in cured patients as well as NO production in cured hamsters and stimulated remarkable Th1-type cellular responses including IFN-ã and IL-12 with extremely lower level of IL-10 in Leishmania-infected cured/exposed patients PBMCs in vitro. Vaccination with LdTPI-DNA construct protected naive golden hamsters from virulent L. donovani challenge unambiguously (∼90%). The vaccinated hamsters demonstrated a surge in IFN-ã, TNF-á and IL-12 levels but extreme down-regulation of IL-10 and IL-4 along with profound delayed type hypersensitivity and increased levels of Leishmania-specific IgG2 antibody. Thus, the results are suggestive of the protein having the potential of a strong candidate vaccine

Comparison of biochemical and anthropometric parameters in complicated and uncomplicated severe acute malnutrition among children aged 6 to 59 months: a cross-sectional study

Aim: The frequency of severe acute malnutrition (SAM) is the highest in India. Although it should receive more attention, severe anemia is one of the comorbidities that increases mortality in children who are severely undernourished. In SAM children, the liver function test (LFT), kidney function test (KFT), and complete blood count (CBC) are deranged, but their correlation with the prognosis is not well defined. The aim was to describe the anthropometric assessment and biochemical profile of children with SAM. Methods: This cross-sectional cohort study was performed at the Departments of Paediatrics and Biochemistry at G.S.V.M. Medical College, Kanpur, and at the Department of Biotechnology at Amity University Rajasthan, Jaipur. One hundred and six patients with SAM were enrolled; 53 were grouped as complicated SAM (Group 1) (dehydration and severe dehydration) and 53 were diagnosed as non-complicated SAM (Group 2). Results: Group II had significantly higher mean values for height, weight, mid-upper arm circumference (MUAC), head circumference, and body mass index (BMI) for age percentile compared to Group I, with P-values of 0.001. Group I had a significantly lower level of hemoglobin (8.86 g/dL ± 2.21 g/dL) compared to Group II (10.0 g/dL ± 1.83 g/dL) with a P-value of 0.003. The difference in the frequency of anemia between the groups was statistically significant, with a P-value of 0.026. Anemia significantly increased the risk of complicated SAM with an odds ratio of 2.60 [95% confidence interval (CI), 1.07–6.31, P = 0.001]. Conclusions: This study suggests that there may be a significant relationship between anemia and the development of complications in high-risk children with SAM

Introduction to Alginate: Biocompatible, Biodegradable, Antimicrobial Nature and Various Applications

Alginate is a polysaccharide that has found numerous applications in the domain of pharmaceutical science, paper and textile industry, food industry, dental applications, welding roads, mucoadhesive properties, scaffolding, biomedical and engineering due to its cost-effective nature, film forming ability, gelling, biocompatibility, biodegradability, nontoxic, non-immunogenic, readily availability, antimicrobial nature. Hydrogels of alginates play a crucial role in well-controlled or sustained release drug delivery, wound healing, and tissue engineering. This book chapter will provide a detailed overview of Alginate and its applications. To the best of our knowledge there no such type of informative data is available on Alginate and its relation with drug susceptibility. Here we more focused on the antibiotic capability of Alginate and its association with bacterial resistance