46 research outputs found
Performance simulation of climate adaptive building shells - Smart Energy Glass as a case study
As opposed to traditional building shells, climate adaptive building shells (CABS) do have the ability to change their properties and behavior over time. Provided they are designed and operated effectively, CABS offer the potential for energy savings without the need for compromising comfort levels. This paper explores the role that building performance simulation (BPS) can play in designing CABS. After analyzing the distinguishing characteristics of CABS, the need for BPS is introduced. The potential role of BPS is then illustrated via the case study of Smart Energy Glass. Based on a description of underlying physics, the model abstraction process is discussed first. This results in an integrated model for performance simulations that couples TRNSYS and DAYSIM. This model is empirically validated and subsequently used to evaluate the potential of Smart Energy Glass in a renovation case under various operational scenario’s. The paper concludes with some suggestions for future research and development of Smart Energy Glass
Prestatiesimulatie van adaptieve gevels - Smart Energy Glass als case-study
In tegenstelling tot traditionele gevels bieden adaptieve gevels de mogelijkheid om slim in te spelen op veranderende binnen- en buitenomstandigheden. Het succesvol ontwerpen van adaptieve gevels blijkt echter een complexe opgave waardoor toepassing van dit beloftevolle concept in de praktijk vooralsnog beperkt is. Dit artikel gaat in op de rol die gebouwsimulatie kan spelen in het ontwerpproces van adaptieve façades en illustreert dit aan de hand van Smart Energy Glass. De modelvorming en simulatiestrategie worden beschreven, waarna de prestaties van het concept zijn beoordeeld op basis van integrale simulaties voor verwarming, koeling, daglicht en elektriciteit. Het artikel concludeert dat adaptieve gevels kunnen bijdragen aan het bereiken van de steeds scherpere energiedoelstellingen zonder daarbij te hoeven tornen aan comfortbeleving. Gebouwsimulatie vormt een belangrijke schakel voor het bereiken van dit doel
Healthy environments from a broad perspective : an overview of research performed at the unit Building Physics and Systems of Eindhoven University of Technology
The design and realization of a healthy indoor environment is a challenge that is investigated from different perspectives at the unit Building Physics and Systems (BPS; Faculty of Architecture, Building and Planning) of Eindhoven University of Technology. Performance requirements (for instance, with respect to air quality, thermal comfort and lighting) and performance based assessment methods are the point-of-departure, focusing at computational techniques supporting the design process. Different specific application fields such as dwellings, offices, schools, but also, operating theatres, churches, musea and multifunctional stadiums, underline the applied approach that is part of the research within the unit. In the design of healthy environments, the performance based design assessment is crucial in arriving at innovative design solutions and optimized indoor and outdoor environments. In this assessment computational support tools and experimental verification play an important role. However, assessing the right indicators in an objective way, applying the correct tools and correct application of these tools is not yet well established. Alongside, developments are still ongoing. The work performed in the unit by the different researchers relates to the research questions that can be derived from this notice. The paper gives an introduction to the Unit BPS and presents a brief overview of recent and ongoing research. An extensive list of references is provided for further reading and supports the conclusion that healthy environments can and should be addressed from a wide angle
Healthy environments from a broad perspective : an overview of research performed at the unit Building Physics and Systems of Eindhoven University of Technology
The design and realization of a healthy indoor environment is a challenge that is investigated from different perspectives at the unit Building Physics and Systems (BPS; Faculty of Architecture, Building and Planning) of Eindhoven University of Technology. Performance requirements (for instance, with respect to air quality, thermal comfort and lighting) and performance based assessment methods are the point-of-departure, focusing at computational techniques supporting the design process. Different specific application fields such as dwellings, offices, schools, but also, operating theatres, churches, musea and multifunctional stadiums, underline the applied approach that is part of the research within the unit. In the design of healthy environments, the performance based design assessment is crucial in arriving at innovative design solutions and optimized indoor and outdoor environments. In this assessment computational support tools and experimental verification play an important role. However, assessing the right indicators in an objective way, applying the correct tools and correct application of these tools is not yet well established. Alongside, developments are still ongoing. The work performed in the unit by the different researchers relates to the research questions that can be derived from this notice. The paper gives an introduction to the Unit BPS and presents a brief overview of recent and ongoing research. An extensive list of references is provided for further reading and supports the conclusion that healthy environments can and should be addressed from a wide angle
The Application of a Semantic-Based Process Mining Framework on a Learning Process Domain
The process mining (PM) field combines techniques
from computational intelligence which has been lately considered
to encompass artificial intelligence (AI) or even the latter,
augmented intelligence (AIs) systems, and the data mining (DM)
to process modelling in order to analyze event logs. To this end, this
paper presents a semantic-based process mining framework
(SPMaAF) that exhibits high level of accuracy and conceptual
reasoning capabilities particularly with its application in real
world settings. The proposed framework proves useful towards
the extraction, semantic preparation, and transformation of
events log from any domain process into minable executable
formats – with focus on supporting the further process of
discovering, monitoring and improvement of the extracted
processes through semantic-based analysis of the discovered
models. Practically, the implementation of the proposed
framework demonstrates the main contribution of this paper; as
it presents a Semantic-Fuzzy mining approach that makes use of
labels (i.e. concepts) within event logs about a domain process
using a case study of the Learning Process. The paper provides a
method which aims to allow for mining and improved analysis of
the resulting process models through semantic – labelling
(annotation), representation (ontology) and reasoning (reasoner).
Consequently, the series of experimentations and semantically
motivated algorithms shows that the proposed framework and its
main application in real-world has the capacity of enhancing the
PM results or outcomes from the syntactic to a much more
abstraction levels
Protein–Protein Interactions Modulate the Docking-Dependent E3-Ubiquitin Ligase Activity of Carboxy-Terminus of Hsc70-Interacting Protein (CHIP)
CHIP is a tetratricopeptide repeat (TPR) domain protein that functions as an E3-ubiquitin ligase. As well as linking the molecular chaperones to the ubiquitin proteasome system, CHIP also has a docking-dependent mode where it ubiquitinates native substrates, thereby regulating their steady state levels and/or function. Here we explore the effect of Hsp70 on the docking-dependent E3-ligase activity of CHIP. The TPR-domain is revealed as a binding site for allosteric modulators involved in determining CHIP's dynamic conformation and activity. Biochemical, biophysical and modeling evidence demonstrate that Hsp70-binding to the TPR, or Hsp70-mimetic mutations, regulate CHIP-mediated ubiquitination of p53 and IRF-1 through effects on U-box activity and substrate binding. HDX-MS was used to establish that conformational-inhibition-signals extended from the TPR-domain to the U-box. This underscores inter-domain allosteric regulation of CHIP by the core molecular chaperones. Defining the chaperone-associated TPR-domain of CHIP as a manager of inter-domain communication highlights the potential for scaffolding modules to regulate, as well as assemble, complexes that are fundamental to protein homeostatic control.Published versio
Climate adaptive building shells : state-of-the-art and future challenges
Successful building design is becoming an increasingly complex task, due to a growing demand to satisfy more ambitious environmental, societal and economical performance requirements. The application of climate adaptive building shells (CABS) has recently been put forward as a promising alternative within this strive for higher levels of sustainability in the built environment. Compared to conventional façades, CABS offer potential opportunities for energy savings as well improvement of indoor environmental quality. By combining the complementary beneficial aspects of both active and passive building technologies into the building envelope, CABS can draw upon the concepts of adaptability, multi-ability and evolvability. The aim of this paper is to present a comprehensive review of research, design and development efforts in the field of CABS. Based on a structured literature review, a classification of 44 CABS is made to place the variety of concepts in context with each other, and concurrent developments. In doing so, the overall motivations, enabling technologies, and characteristic features that have contributed to the development of CABS are highlighted. Despite the positive perspectives, it was found that the concept of CABS cannot yet be considered mature. Future research needs and further challenges to be resolved are therefore identified as well
Tephrostratigraphy Studies at Kings Bowl, Craters of the Moon National Monument and Preserve
The Kings Bowl pit was formed by a phreatic blast through a solidifying lava lake at Craters of the Moon National Monument and Preserve, Idaho, around 2000 years ago. The blast produced a tephra deposit that was carried eastward by the wind, leaving only ballistic ejecta on the west side of the blast site. In the summer of 2015 we conducted a tephrostratigraphic study of the deposits to evaluate the style of the blast in conjunction with the NASA FINESSE project. Data was obtained by digging holes and recording the depth, collecting samples from the inside wall of the hole, and recording any in situ tephrostratigraphy. Bioturbation caused by sagebrush resulted in only one hole showing preserved tephrostratigraphy for two fall units. Therefore the rest of the holes were reported as bulk, the result of mixing of an unknown number of units. Not only was there extensive bioturbation, there was also extensive eolian dust. Isopach and isopleth maps of the tephra deposit support the hypothesis that there were at least three blasting events. This indicates that the phreatic blasts at Kings Bowl were more complex than previously recognized
Prestatiesimulatie van adaptieve gevels
Adaptieve gevels bieden de mogelijkheid om slim in te spelen op veranderende binnen- en buitenomstandigheden. Dit in tegenstelling tot traditionele gevels.Maar toepassing in de praktijk blijft vooralsnog beperkt, ondanks het beloftevolle concept. Dit artikel gaat in op de rol die gebouwsimulatie kan spelen in het ontwerpproces van adaptieve façades en illustreert dit aan de hand van Smart Energy Glass. De conclusie is dat adaptieve gevels kunnen bijdragen aan het bereiken van de steeds scherpere energiedoelstellingen, zonder te hoeven tornen aan comfortbeleving. Gebouwsimulatie vormt daarbij een belangrijke schakel
Prestatiesimulatie van adaptieve gevels
Adaptieve gevels bieden de mogelijkheid om slim in te spelen op veranderende binnen- en buitenomstandigheden. Dit in tegenstelling tot traditionele gevels.Maar toepassing in de praktijk blijft vooralsnog beperkt, ondanks het beloftevolle concept. Dit artikel gaat in op de rol die gebouwsimulatie kan spelen in het ontwerpproces van adaptieve façades en illustreert dit aan de hand van Smart Energy Glass. De conclusie is dat adaptieve gevels kunnen bijdragen aan het bereiken van de steeds scherpere energiedoelstellingen, zonder te hoeven tornen aan comfortbeleving. Gebouwsimulatie vormt daarbij een belangrijke schakel