192 research outputs found
Sugars are under light control during bud burst in Rosa sp.
Bud burst in certain species is conditioned by the luminous environment. With roses, the requirement for light is absolute, and darkness totally inhibits bud burst. Few studies have looked into understanding the action of light on the physiological bud burst processes. Here, we show the impact of light on certain components of glucidic metabolism during bud burst. Measurements were taken on decapitated plants of Rosa hybrida L. âRadrazzâ exposed either to darkness, white, blue or R light. Results show that a mobilization of bud and the carrying stem sucrose reserves only takes place in light and accompanies the bud burst. Furthermore, the activity of the RhVI vacuolar acid invertase which contributes to the breakdown of sucrose in the buds, as well as the transcription of the RhVI gene, is reduced in darkness, although it is strongly stimulated by light. The same analysis concerning the RhNAD-SDH gene, coding an NAD-dependent sorbitol dehydrogenase, shows, on the contrary, a strong induction of its transcription in darkness that could reflect the use of survival mechanisms in this condition
High current density electron beam generation from field emission tip cathodes
Electron beams with current up to 1.2 A and current density over 10(7) A/cm2 have been generated from a pulsed field emission tip cathode etched from commercial grade tungsten wire. Electron beams with current up to 0.8 A have also been generated from a molybdenum tip. Tip radius was 0.1-1 mum. Applied tip voltage was up to 50 kV with pulse duration of 0.3-1.2 mus. Depending on brightness, these types of electron beams could be suitable for channeling radiation x-ray lasers and might considerably decrease the operating wavelength of free-electron lasers at moderate beam energies
Effects of an 18-week exercise programme started early during breast cancer treatment: a randomised controlled trial
Background: Exercise started shortly after breast cancer diagnosis might prevent or diminish fatigue complaints. The Physical Activity during Cancer Treatment (PACT) study was designed to primarily examine the effects of an 18-week exercise intervention, offered in the daily clinical practice setting and starting within 6 weeks after diagnosis, on preventing an increase in fatigue. Methods: This multi-centre controlled trial randomly assigned 204 breast cancer patients to usual care (n = 102) or supervised aerobic and resistance exercise (n = 102). By design, all patients received chemotherapy between baseline and 18 weeks. Fatigue (i.e., primary outcome at 18 weeks), quality of life, anxiety, depression, and physical fitness were measured at 18 and 36 weeks. Results: Intention-to-treat mixed linear model analyses showed that physical fatigue increased significantly less during cancer treatment in the intervention group compared to control (mean between-group differences at 18 weeks: -1.3; 95 % CI -2.5 to -0.1; effect size -0.30). Results for general fatigue were comparable but did not reach statistical significance (-1.0, 95% CI -2.1; 0.1; effect size -0.23). At 18 weeks, submaximal cardiorespiratory fitness and several muscle strength tests (leg extension and flexion) were significantly higher in the intervention group compared to control, whereas peak oxygen uptake did not differ between groups. At 36 weeks these differences were no longer statistically significant. Quality of life outcomes favoured the exercise group but were not significantly different between groups. Conclusions: A supervised 18-week exercise programme offered early in routine care during adjuvant breast cancer treatment showed positive effects on physical fatigue, submaximal cardiorespiratory fitness, and muscle strength. Exercise early during treatment of breast cancer can be recommended. At 36 weeks, these effects were no longer statistically significant. This might have been caused by the control participants' high physical activity levels during follow-up
Sensory profiles and preference analysis in ornamental horticulture: The case of the rosebush
The context of ornamental horticulture is considered in order to extend the techniques of sensory and preference evaluation by taking the rosebush as a plant model. In a preliminary study (Boumaza, Demotes-Mainard, Huché-Thélier, & Guérin, 2009), a sensory evaluation was conducted in order to set up a list of attributes. Subsequently, this list was adapted to assess 10 rosebushes. After the control of the panel performance using a multivariate strategy of analysis, the average scores were used in product mapping. The evaluation of the preferences with regard to these rosebushes was undertaken: 253 subjects were asked to rank the products by decreasing order of liking. Thereafter, the preference data were subjected to an internal preference mapping and a cluster analysis. Six homogeneous segments of consumers were eventually retained. By way of performing an external preference mapping, the average ranks were regressed upon the sensory attributes using principal component regression: the preferences of 67% of the consumers were satisfactorily explained by the attributes
Feasibility of a 12-month-exercise intervention during and after radiation and chemotherapy in cancer patients: impact on quality of life, peak oxygen consumption, and body composition
Cancer morbidity in Swedish dry-cleaners and laundry workers: historically prospective cohort study
Insight into the Role of Sugars in Bud Burst Under Light in the Rose
Bud burst is a decisive process in plant architecture that requires light in Rosa sp. This light effect was correlated with stimulation of sugar transport and metabolism in favor of bud outgrowth. We investigated whether sugars could act as signaling entities in the light-mediated regulation of vacuolar invertases and bud burst. Full-length cDNAs encoding two vacuolar invertases (RhVI1 and RhVI2) were isolated from buds. Unlike RhVI2, RhVI1 was preferentially expressed in bursting buds, and was up-regulated in buds of beheaded plants exposed to light. To assess the importance of sugars in this process, the expression of RhVI1 and RhVI2 and the total vacuolar invertase activity were further characterized in buds cultured in vitro on 100 mM sucrose or mannitol under light or in darkness for 48 h. Unlike mannitol, sucrose promoted the stimulatory effect of light on both RhVI1 expression and vacuolar invertase activity. This up-regulation of RhVI1 was rapid (after 6 h incubation) and was induced by as little as 10 mM sucrose or fructose. No effect of glucose was found. Interestingly, both 30 mM palatinose (a non-metabolizable sucrose analog) and 5 mM psicose (a non-metabolizable fructose analog) promoted the light-induced expression of RhVI1 and total vacuolar invertase activity. Sucrose, fructose, palatinose and psicose all promoted bursting of in vitro cultured buds under light. These findings indicate that soluble sugars contribute to the light effect on bud burst and vacuolar invertases, and can function as signaling entities
Relationship between smoking and obesity:a cross-sectional study of 499,504 middle-aged adults in the UK general population
Background:
There is a general perception that smoking protects against weight gain and this may influence commencement and continuation of smoking, especially among young women.<p></p>
Methods:
A cross-sectional study was conducted using baseline data from UK Biobank. Logistic regression analyses were used to explore the association between smoking and obesity; defined as body mass index (BMI) >30kg/m2. Smoking was examined in terms of smoking status, amount smoked, duration of smoking and time since quitting and we adjusted for the potential confounding effects of age, sex, socioeconomic deprivation, physical activity, alcohol consumption, hypertension and diabetes.<p></p>
Results:
The study comprised 499,504 adults aged 31 to 69 years. Overall, current smokers were less likely to be obese than never smokers (adjusted OR 0.83 95% CI 0.81-0.86). However, there was no significant association in the youngest sub-group (â€40 years). Former smokers were more likely to be obese than both current smokers (adjusted OR 1.33 95% CI 1.30-1.37) and never smokers (adjusted OR 1.14 95% CI 1.12-1.15). Among smokers, the risk of obesity increased with the amount smoked and former heavy smokers were more likely to be obese than former light smokers (adjusted OR 1.60, 95% 1.56-1.64, p<0.001). Risk of obesity fell with time from quitting. After 30 years, former smokers still had higher risk of obesity than current smokers but the same risk as never smokers.<p></p>
Conclusion:
Beliefs that smoking protects against obesity may be over-simplistic; especially among younger and heavier smokers. Quitting smoking may be associated with temporary weight gain. Therefore, smoking cessation interventions should include weight management support.<p></p>
Plant responses to red and far-red lights, applications in horticulture
Light drives plant growth and development, so its control is increasingly used as an environment-friendly tool to manage horticultural crops. However, this implies a comprehensive view of the main physiological processes under light control, and bridging knowledge gaps. This review presents the state of the art in i) perception of red (R) and far-red (FR) wavelengths and of the R:FR ratio by plants, ii) phenotypic plant responses, and iii) the molecular mechanisms related to these responses. Changes in red or far red radiation and R:FR ratios are perceived by phytochromes. Phytochrome-mediated regulation is complex and specific to each physiological process. Our review presents the effects of red and far-red lights on germination, aerial architectural development, flowering, photosynthesis and plant nutrition. It also addresses how red and far-red radiations interact with tolerance to drought, pathogens and herbivores. Current knowledge about the mechanisms whereby red, far-red and R:FR regulate these different processes is presented. The specific actors of light signal transduction are better known for germination or flowering than for other processes such as internode elongation or bud outgrowth. The phenotypic response to red, far-red and R:FR can vary among species, but also with growing conditions. The mechanisms underlying these differences in plant responses still need to be unveiled. Current knowledge about plants\u27 response to light is being applied in horticulture to improve crop yield and quality. To that purpose, it is now possible to manipulate light quality thanks to recent technological evolutions such as the development of photo-selective films and light-emitting diodes
The Influence of hormonal factors on the risk of developing cervical cancer and pre-cancer: results from the EPIC cohort
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