High-Brightness Photocathode Electron Sources

Most present and future electron accelerators require bright sources. Invented less than ten years ago, the photo-injector the principle of which is briefly recalled, has already demonstrated that it can provide very bright beams. In this paper, the most advanced photo-injector projects are reviewed, their specific features are outlined, and their major issues are examined. The state-of-the-art in photocathode and laser technologies is presented. Beam dynamics issues are also considered since they are essential in the production of bright beams. Finally, the question of the maturity of photo-injector technology is addressed.Comment: PostScript uuencoded file, 18 pages, 5 figure

Laser cooling of electron beams for linear colliders

A novel method of electron beam cooling is considered which can be used for linear colliders. The electron beam is cooled during collision with focused powerful laser pulse. With reasonable laser parameters (laser flash energy about 10 J) one can decrease transverse beam emittances by a factor about 10 per one stage. The ultimate transverse emittances are much below those achievable by other methods. Beam depolarization during cooling is about 5--15 % for one stage. This method is especially useful for photon colliders and opens new possibilities for e+e- colliders.Comment: 4 pages, Latex, v2 corresponds to the PRL paper with erratum (in 1998) include

Candela photo-injector experimental results with a dispenser photocathode

International audienceThe CANDELA photo-injector is a two cell S-band photo-injector. The dispenser photocathode is illuminated by a 500 fs pulse from a frequency-tripled Ti:sapphire laser. In this paper we report charge measurements showing that the dispenser photocathode has a quantum efficiency as high as 10-3. This efficiency decreases with a lifetime of 12 hours, but can be recovered by heating the cathode for 5 minute

Light and nitrogen nutrition regulate apical control in Rosa hybrida L.

Apical control is defined as the inhibition of basal axillary bud outgrowth by an upper actively growing axillary axis, whose regulation is poorly understood yet differs markedly from the better-known apical dominance. We studied the regulation of apical control by environmental factors in decapitated Rosa hybrida in order to remove the apical hormonal influence and nutrient sink. In this plant model, all the buds along the main axis have a similar morphology and are able to burst in vitro. We concentrated on the involvement of light intensity and nitrate nutrition on bud break and axillary bud elongation in the primary axis pruned above the fifth leaf of each rose bush. We observed that apical control took place in low light (92 μmol m−2 s−1), where only the 2-apical buds grew out, both in low (0.25 mM) and high (12.25 mM) nitrate. In contrast, in high light (453 μmol m−2 s−1), the apical control only operates in low nitrate while all the buds along the stem grew out when the plant was supplied with a high level of nitrate. We found a decreasing photosynthetic activity from the top to the base of the plant concomitant with a light gradient along the stem. The quantity of sucrose, fructose, glucose and starch are higher in high light conditions in leaves and stem. The expression of the sucrose transporter RhSUC2 was higher in internodes and buds in this lighting condition, suggesting an increased capacity for sucrose transport. We propose that light intensity and nitrogen availability both contribute to the establishment of apical control

Identifying High-risk Individuals For Lung Cancer Screening: Going Beyond Nlst Criteria

Background There are two main types of strategies to identify target population for lung cancer screening: 1) strategies based on age and cumulative smoking criteria, 2) risk prediction models allowing the calculation of an individual risk. The objective of this study was to compare different strategies to identify the proportion of the Spanish population at high risk of developing lung cancer, susceptible to be included in a lung cancer screening programme. Methods Cross-sectional study. We used the data of the Spanish National Interview Health Survey (ENSE) of 2011-2012 (21,006 individuals) to estimate the proportion of participants at high risk of developing lung cancer. This estimation was performed using the U.S. national lung screening trial (NLST) criteria and a 6-year prediction model (PLCOm2012), both independently and in combination. Results The prevalence of individuals at high risk of developing lung cancer according to the NLST criteria was 4.9% (7.9% for men, 2.4% for women). Among the 1,034 subjects who met the NLST criteria, 533 (427 men and 106 women) had a 6-year lung cancer risk >= 2.0%. The combination of these two selection strategies showed that 2.5% of the Spanish population had a high risk of developing lung cancer. However, this selection process did not take into account different groups of subjects = 2%, such as heavy smokers <55 years old who were long-time former smokers, and ever smokers having smoked <30 pack-years with other risk factors. Conclusions Further research is needed to determine which selection strategy achieves a higher benefit/harm ratio and to assess other prevention strategies for individuals with elevated risk for lung cancer but who do not meet the screening eligibility criteria