Extraction and Quantification of Carpaine from Carica papaya Leaves of Vietnam

Our previous research indicated that carpaine and its derivative pseudocarpaine extracted from Carica papaya leaves had anti-cancer activity. In this study, we extracted the total alkaloid from Carica papaya leaves, then extracted carpaine and quantitative analyzed carpaine in the total alkaloid. Carica papaya leaves was crushed, and then extracted with EtOH to obtain the total extract. This extract was extracted with suitable solvent to obtain total alkaloid. Continued to extract the total alkaloid by using open column chromatography and crystallizing method to purify carpaine. The research result showed that the total alkaloid in Carica papaya leaves was 0.2% comparing with dried material. Quantitative analyze of purified carpaine by HPLC determined that carpaine was the main alkaloid with the content was 63% of the total alkaloid extracted from Carica papaya leaves

Time switching for wireless communications with full-duplex relaying in imperfect CSI condition

In this paper, we consider an amplify-and-forward (AF) full-duplex relay network (FDRN) using simultaneous wireless information and power transfer, where a battery-free relay node harvests energy from the received radio frequency (RF) signals from a source node and uses the harvested energy to forward the source information to destination node. The time-switching relaying (TSR) protocol is studied, with the assumption that the channel state information (CSI) at the relay node is imperfect. We deliver a rigorous analysis of the outage probability of the proposed system. Based on the outage probability expressions, the optimal time switching factor are obtained via the numerical search method. The simulation and numerical results provide practical insights into the effect of various system parameters, such as the time switching factor, the noise power, the energy harvesting efficiency, and the channel estimation error on the performance of this network. It is also observed that for the imperfect CSI case, the proposed scheme still can provide acceptable outage performance given that the channel estimation error is bounded in a permissible interval.Web of Science1094239422

A Schrödinger Equation for Evolutionary Dynamics

We establish an analogy between the Fokker–Planck equation describing evolutionary landscape dynamics and the Schrödinger equation which characterizes quantum mechanical particles, showing that a population with multiple genetic traits evolves analogously to a wavefunction under a multi-dimensional energy potential in imaginary time. Furthermore, we discover within this analogy that the stationary population distribution on the landscape corresponds exactly to the ground-state wavefunction. This mathematical equivalence grants entry to a wide range of analytical tools developed by the quantum mechanics community, such as the Rayleigh–Ritz variational method and the Rayleigh–Schrödinger perturbation theory, allowing us not only the conduct of reasonable quantitative assessments but also exploration of fundamental biological inquiries. We demonstrate the effectiveness of these tools by estimating the population success on landscapes where precise answers are elusive, and unveiling the ecological consequences of stress-induced mutagenesis—a prevalent evolutionary mechanism in pathogenic and neoplastic systems. We show that, even in an unchanging environment, a sharp mutational burst resulting from stress can always be advantageous, while a gradual increase only enhances population size when the number of relevant evolving traits is limited. Our interdisciplinary approach offers novel insights, opening up new avenues for deeper understanding and predictive capability regarding the complex dynamics of evolving populations

Design an Intelligent System to automatically Tutor the Method for Solving Problems

Nowadays, intelligent systems have been applied in many real-word domains. The Intelligent chatbot is an intelligent system, it can interact with the human to tutor how to work some activities. In this work, we design an architecture to build an intelligent chatbot, which can tutor to solve problems, and construct scripts for automatically tutoring. The knowledge base of the intelligent tutoring chatbot is designed by using the requirements of an Intelligent Problem Solver. It is the combination between the knowledge model of relations and operators, and the structures of hint questions and sample problems, which are practical cases. Based on the knowledge base and tutoring scripts, a tutoring engine is designed. The tutoring chatbot plays as an instructor for solving real-world problems. It simulates the working of the instructor to tutor the user for solving problems. By utilizing the knowledge base and reasoning, the architecture of the intelligent chatbot are emerging to apply in the real-world. It is used to build an intelligent chatbot to support the learning of high-school mathematics and a consultant system in public administration. The experimental results show the effectiveness of the proposed method in comparison with the existing systems

A Schr\"odinger Equation for Evolutionary Dynamics

We establish an analogy between the Fokker-Planck equation describing evolutionary landscape dynamics and the Schr\"{o}dinger equation which characterizes quantum mechanical particles, showing how a population with multiple genetic traits evolves analogously to a wavefunction under a multi-dimensional energy potential in imaginary time. Furthermore, we discover within this analogy that the stationary population distribution on the landscape corresponds exactly to the ground-state wavefunction. This mathematical equivalence grants entry to a wide range of analytical tools developed by the quantum mechanics community, such as the Rayleigh-Ritz variational method and the Rayleigh-Schr\"{o}dinger perturbation theory, allowing us to not only make reasonable quantitative assessments but also explore fundamental biological inquiries. We demonstrate the effectiveness of these tools by estimating the population success on landscapes where precise answers are elusive, and unveiling the ecological consequences of stress-induced mutagenesis -- a prevalent evolutionary mechanism in pathogenic and neoplastic systems. We show that, even in a unchanging environment, a sharp mutational burst resulting from stress can always be advantageous, while a gradual increase only enhances population size when the number of relevant evolving traits is limited. Our interdisciplinary approach offers novel insights, opening up new avenues for deeper understanding and predictive capability regarding the complex dynamics of evolving populations

POLLUTION OF GROUNDWATER BY LEACHATE FROM DONG THANH LANDFILL DISPOSAL SITE

Joint Research on Environmental Science and Technology for the Eart