1,411 research outputs found
Development of Spherical Ultrasonic Motor for Critical Environment
In recent years, due to advances in science technology, space satellites have made progress. So, the presence of space debris has become problem in the world because they may collide each other. In our study, we have developed Spherical Ultrasonic Motor (SUSM) for space use with 3 DOF to drive the satellite thruster and resolve it. We aim that the satellites enter the atmosphere when the satellites reached the end of life, and SUSM controls thrusters when they inject for the directional control. We have made experiments of measuring torque, durability and lifetime. It shows that the torque and lifetime meets target value. But durability does not meet target value. To resolve it, we have applied stator lining materials and shifted frequency with 0.4kHz from resonant frequency and we have shown that it meets durability required specifications
Persistence of donor cells and incidence of graft-versus-host disease after simultaneous small bowel and bone marrow transplantation
Diabetic Cardiovascular Disease Induced by Oxidative Stress.
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among patients with diabetes mellitus (DM). DM can lead to multiple cardiovascular complications, including coronary artery disease (CAD), cardiac hypertrophy, and heart failure (HF). HF represents one of the most common causes of death in patients with DM and results from DM-induced CAD and diabetic cardiomyopathy. Oxidative stress is closely associated with the pathogenesis of DM and results from overproduction of reactive oxygen species (ROS). ROS overproduction is associated with hyperglycemia and metabolic disorders, such as impaired antioxidant function in conjunction with impaired antioxidant activity. Long-term exposure to oxidative stress in DM induces chronic inflammation and fibrosis in a range of tissues, leading to formation and progression of disease states in these tissues. Indeed, markers for oxidative stress are overexpressed in patients with DM, suggesting that increased ROS may be primarily responsible for the development of diabetic complications. Therefore, an understanding of the pathophysiological mechanisms mediated by oxidative stress is crucial to the prevention and treatment of diabetes-induced CVD. The current review focuses on the relationship between diabetes-induced CVD and oxidative stress, while highlighting the latest insights into this relationship from findings on diabetic heart and vascular disease
A Reduction-Preserving Completion for Proving Confluence of Non-Terminating Term Rewriting Systems
We give a method to prove confluence of term rewriting systems that contain
non-terminating rewrite rules such as commutativity and associativity. Usually,
confluence of term rewriting systems containing such rules is proved by
treating them as equational term rewriting systems and considering E-critical
pairs and/or termination modulo E. In contrast, our method is based solely on
usual critical pairs and it also (partially) works even if the system is not
terminating modulo E. We first present confluence criteria for term rewriting
systems whose rewrite rules can be partitioned into a terminating part and a
possibly non-terminating part. We then give a reduction-preserving completion
procedure so that the applicability of the criteria is enhanced. In contrast to
the well-known Knuth-Bendix completion procedure which preserves the
equivalence relation of the system, our completion procedure preserves the
reduction relation of the system, by which confluence of the original system is
inferred from that of the completed system
Edema Induced by sPLA2 from <em>Crotalus durissus terrificus</em> Involves PLC and PKC Signaling, Activation of cPLA2, and Oxidative Stress
sPLA2 from Crotalus durissus terrificus venom, free of crotapotin (Cdt sPLA2), purified and isolated sPLA2, was able to significantly increase lipid peroxidation, which occurred simultaneously with increased arachidonic acid (AA) metabolism. In addition, MDA and AA levels were elevated at 15 min after Cdt sPLA2 injection and after peak edema (negative control). Thus, oxidative stress and ROS play important roles in the inflammation induced by Cdt sPLA2. On the other hand, edema induced by sPLA2 involves the direct and indirect mobilization of arachidonic acid by the involvement of phosphokinase C (PKC) and phospholipase C (PLC), which indirectly stimulates cytosolic PLA2 (cPLA2). We also observed that the specific antivenin against Cdt venom had no significant effect on the neutralization of induced edema compared to the natural products 5-caffeine-linoleic acid (5CQA) and dexamethasone (AACOCF3). Our results also indicate that there was improvement in the inhibition of edema of natural polyphenolic compounds compared to antivenin or inhibition of the enzymatic activity of sPLA2 due to the fact that 5CQA is a potent antioxidant compound. Thus, our results show a clear correlation between increased arachidonic acid metabolism and oxidative stress
Study of a Threshold Cherenkov Counter Based on Silica Aerogels with Low Refractive Indices
To identify and in the region of GeV/c, a
threshold Cherenkov counter equipped with silica aerogels has been
investigated. Silica aerogels with a low refractive index of 1.013 have been
successfully produced using a new technique. By making use of these aerogels as
radiators, we have constructed a Cherenkov counter and have checked its
properties in a test beam. The obtained results have demonstrated that our
aerogel was transparent enough to make up for loss of the Cherenkov photon
yield due to a low refractive index. Various configurations for the photon
collection system and some types of photomultipliers, such as the fine-mesh
type, for a read out were also tested. From these studies, our design of a
Cherenkov counter dedicated to separation up to a few GeV/c %in the
momentum range of GeV/c with an efficiency greater than \%
was considered.Comment: 21 pages, latex format (article), figures included, to be published
in Nucl. Instrm. Meth.
- …