Design and performance of a 39cm balloon-borne telescope

A system for stabilizing a balloon-borne telescope using a star sensor device is described. Guide stars from minus four to plus four magnitude can be used and the sensor may be offset with respect to the telescope by as much as plus or minus five degrees in elevation and cross elevation to enable parts of the sky containing no suitable guide stars to be viewed. Acquisition of the guide star and setting of the offset coordinates is carried out by ground command and both may be changed in flight. The main design parameters of the equipment are summarized. Block diagrams and circuit diagrams of the star tracker are provided

Cryogenic mechanisms for scanning and interchange of the Fabry-Perot interferometers in the ISO long wavelength spectrometer

The Infrared Space Observatory (ISO) is an ESA cornerstone mission for infrared astronomy. Schedules for launch in 1993, its four scientific instruments will provide unprecedented sensitivity and spectral resolution at wavelengths which are inaccessible using ground-based techniques. One of these, the Long Wavelength Spectrometer (LWS), will operate in the 45 to 180 micron region (Emery et. al., 1985) and features two Fabry-Perot interferometers mounted on an interchange mechanism. The entire payload module of the spacecraft, comprising the 60 cm telescope and the four focal plane instruments, is maintained at 2 to 4 K by an onboard supply of liquid helium. The mechanical design and testing of the cryogenic interferometer and interchange mechanisms are described

Prediction and Topological Models in Neuroscience

In the last two decades, philosophy of neuroscience has predominantly focused on explanation. Indeed, it has been argued that mechanistic models are the standards of explanatory success in neuroscience over, among other things, topological models. However, explanatory power is only one virtue of a scientific model. Another is its predictive power. Unfortunately, the notion of prediction has received comparatively little attention in the philosophy of neuroscience, in part because predictions seem disconnected from interventions. In contrast, we argue that topological predictions can and do guide interventions in science, both inside and outside of neuroscience. Topological models allow researchers to predict many phenomena, including diseases, treatment outcomes, aging, and cognition, among others. Moreover, we argue that these predictions also offer strategies for useful interventions. Topology-based predictions play this role regardless of whether they do or can receive a mechanistic interpretation. We conclude by making a case for philosophers to focus on prediction in neuroscience in addition to explanation alone

The ISO Long-Wavelength Spectrometer

The Long-Wavelength Spectrometer (LWS) is one of two complementary spectrometers aboard the European Space Agency's Infrared Space Observatory (ISO) (Kessler et al., 1996). It operates over the wavelength range 43 - 196.9 μm at either medium (about 150 to 200) or high (6800 to 9700) spectral resolving power. This Letter describes the instrument and its modes of operation; a companion paper (Swinyard et al, 1996) describes its performance and calibration

Calibration and performance of the ISO Long-Wavelength Spectrometer

The wavelength and flux calibration, and the in-orbit performance of the Infrared Space Observatory Long-Wavelength Spectrometer (LWS) are described. The LWS calibration is mostly complete and the instrument's performance in orbit is largely as expected before launch. The effects of ionising radiation on the detectors, and the techniques used to minimise them are outlined. The overall sensitivity figures achieved in practice are summarised. The standard processing of LWS data is described

The ISO/LWS far infrared spectrum of IRC+10 216

We present an ISO Long Wavelength Spectrometer (LWS) grating spectrum of the carbon-rich circumstellar envelope -CSE- of IRC+10216 between 43 and 197μm. The spectrum consists of strong dust emission plus a forest of emission lines from CO, HCN, H^13^CN and vibrationally excited HCN (ν_2_=1^1^,2^0,2^ and ν_1,3_=1). All the CO lines between J=14-13 and J=39-38 have been detected while lines of HCN with J_u_ as high as 48 have also been observed. The molecular emission arises from the warm and dense gas located in the innermost zone of the CSE. The CO and HCN emission can be easily explained if the vibrational and rotational temperatures are around 700-1500 K. We also report the tentative detection of the bending mode of the C_3_ molecule around 62cm^-1^ (157.2μm)

Match-Play and Performance Test Responses of Soccer Goalkeepers: A Review of Current Literature.

Goalkeepers are typically the last defensive line for soccer teams aiming to minimise goals being conceded, with match rules permitting ball handling within a specific area. Goalkeepers are also involved in initiating some offensive plays, and typically remain in close proximity to the goal line while covering ~ 50% of the match distances of outfield players; hence, the competitive and training demands of goalkeepers are unique to their specialised position. Indeed, isolated performance tests differentiate goalkeepers from outfield players in multiple variables. With a view to informing future research, this review summarised currently available literature reporting goalkeeper responses to: (1) match play (movement and skilled/technical demands) and (2) isolated performance assessments (strength, power, speed, aerobic capacity, joint range of motion). Literature searching and screening processes yielded 26 eligible records and highlighted that goalkeepers covered ~ 4-6 km on match day whilst spending ~ 98% of time at low-movement intensities. The most decisive moments are the 2-10 saves·match-1 performed, which often involve explosive actions (e.g. dives, jumps). Whilst no between-half performance decrements have been observed in professional goalkeepers, possible transient changes over shorter match epochs remain unclear. Isolated performance tests confirm divergent profiles between goalkeepers and outfield players (i.e. superior jump performance, reduced [Formula: see text]2max values, slower sprint times), and the training of soccer goalkeepers is typically completed separately from outfield positions with a focus primarily on technical or explosive drills performed within confined spaces. Additional work is needed to examine the physiological responses to goalkeeper-specific training and match activities to determine the efficacy of current preparatory strategies

Micro-connectomics: probing the organization of neuronal networks at the cellular scale.

Defining the organizational principles of neuronal networks at the cellular scale, or micro-connectomics, is a key challenge of modern neuroscience. In this Review, we focus on graph theoretical parameters of micro-connectome topology, often informed by economical principles that conceptually originated with Ramón y Cajal's conservation laws. First, we summarize results from studies in intact small organisms and in samples from larger nervous systems. We then evaluate the evidence for an economical trade-off between biological cost and functional value in the organization of neuronal networks. Various results suggest that many aspects of neuronal network organization are indeed the outcome of competition between these two fundamental selection pressures.This work was supported by the National Institute of Health Research (NIHR) Cambridge Biomedical Research Centre.This is the author accepted manuscript. It is currently under an indefinite embargo pending publication by the Nature Publishing Group