30 research outputs found

    The actual impedance of non-reflecting boundary conditions : implications for the computation of resonators

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    Non-reflecting boundary conditions are essential elements in the computation of many compressible flows: such simulations are very sensitive to the treatment of acoustic waves at boundaries. Non-reflecting conditions allow acoustic waves to propagate through boundaries with zero or small levels of reflection into the domain. However, perfectly non-reflecting conditions must be avoided because they can lead to ill-posed problems for the mean flow. Various methods have been proposed to construct boundary conditions which can be sufficiently non-reflecting for the acoustic field while still making the mean-flow problem well posed. This paper analyses a widely-used technique for non-reflecting outlets (Rudy and Strikwerda, Poinsot and Lele). It shows that the correction introduced by these authors can lead to large reflection levels and non-physical resonant behaviors. A simple scaling is proposed to evaluate the relaxation coefficient used in theses methods for a non-reflecting outlet. The proposed scaling is tested for simple cases (ducts) both theoretically and numerically

    Research Note: A workaround for the corner problem in numerically exact non-reflecting boundary conditions

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    Simulations of wave propagation in the Earth usually require truncation of a larger domain to the region of interest to keep computational cost acceptable. This introduces artificial boundaries that should not generate reflected waves. Most existing boundary conditions are not able to completely suppress all the reflected energy, but suffice in practice except when modelling subtle events such as interbed multiples. Exact boundary conditions promise better performance but are usually formulated in terms of the governing wave equation and, after discretization, still may produce unwanted artefacts. Numerically exact non-reflecting boundary conditions are instead formulated in terms of the discretized wave equation. They have the property that the numerical solution computed on a given domain is the same as one on a domain enlarged to the extent that waves reflected from the boundary do not have the time to reach the original truncated domain. With a second- or higher-order finite-difference scheme for the one-dimensional wave equation, these boundary conditions follow from a recurrence relation. In its generalization to two or three dimensions, a recurrence relation was only found for a single non-reflecting boundary on one side of the domain or two of them at opposing ends. The other boundaries should then be zero Dirichlet or Neumann. If two non-reflecting boundaries meet at a corner, translation invariance is lost and a simple recurrence relation could not be found. Here, a workaround is presented that restores translation invariance by imposing classic, approximately non-reflecting boundary conditions on the other sides and numerically exact ones on the two opposing sides that otherwise would create the strongest reflected waves with the classic condition. The exact ones can also be applied independently. As a proof of principle, the method is applied to the two-dimensional acoustic wave equation, discretized on a rectangular domain with a second-order finite-difference scheme and first-order Enquist–Majda boundary conditions as approximate ones. The method is computationally costly but has the advantage that it can be reused on a sequence of problems as long as the time step and the sound speed values next to the boundary are kept fixed.Accepted Author ManuscriptApplied Geophysics and Petrophysic

    Surface-anchored carbon nanomaterials for antimicrobial surfaces

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    International audienceCarbon nanomaterials (CNMs) are known for their antimicrobial (antibacterial and antiviral) activity when dispersed in a liquid, but whether this can be transferred to the surface of common materials has rarely been investigated. We have compared two typical CNMs (double-walled carbon nanotubes and few-layer graphene) in their non-oxidised and oxidised forms in terms of their antibacterial (Pseudomonas aeruginosa and Staphylococcus aureus) and antiviral (SARS-CoV2) activities after anchoring them onto the surface of silicone. We propose a very simple and effective protocol using the air-brush spray deposition method to entrap CNMs on the surfaces of two different silicone materials and demonstrate that the nanomaterials are anchored within the polymer while still being in contact with bacteria. We also investigated their antiviral activity against SARS-COV2 after deposition on standard surgical respiratory masks. Our results show that while suspensions of double-walled carbon nanotubes had a moderate effect on P. aeruginosa, this was not transferred after anchoring them to the surface of silicone. In contrast, graphene oxide showed a very strong antibacterial effect on P. aeruginosa and oxidised double-walled carbon nanotubes on S. aureus only when anchored to the surface. No significant antiviral activity was observed. This work paves the way for new antibacterial surfaces based on CNMs

    In Vitro Anti-Inflammatory and Immunomodulatory Activities of an Extract from the Roots of Bupleurum rotundifolium

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    This article belongs to the Special Issue Biological Potential and Medical Use of Natural ExtractsInternational audienceBackground: Some Bupleurum species, such as the Bupleurum chinense DC. or the Bupleurum scorzonerifolium Willd have been extensively studied (especially their roots) for the treatment of inflammation. In contrast, only compounds extracted from the aerial parts of Bupleurum rotundifolium have been studied and showed anti-inflammatory or antiproliferative activities. This study was conducted to investigate the antioxidant, anti-inflammatory, and immunomodulatory effects of Bupleurum rotundifolium roots. Methods: To tackle the various aspects of inflammation, we studied in vitro a methanolic extract from the roots of Bupleurum rotundifolium on peripheral blood mononuclear cells (PBMCs), polymorphonuclear neutrophils (PMNs), and the monocytic cells THP-1. Its antioxidant capacities and iron-chelating activity were assessed. The extract was tested on THP-1 differentiation, reactive oxygen species (ROS) production by leukocytes, neutrophils chemotaxis, cytokines, PGE2 production, and NF-κB activation in PBMCs. Results: The extract showed a decreased ROS production in stimulated cells. It increased PBMC chemokine secretion and up-regulated the differentiation of THP-1 monocytes into macrophage-like cells, indicating a potential interest of the extract in the resolution of acute inflammation. In addition, the analysis of cytokine production suggests that Bupleurum rotundifolium has immunomodulatory properties. Conclusions: Cytokines secretion, especially IL-1β and IL-12p70, provided us with a set of indicators suggesting that the extract might be able to drive the polarization of macrophages and lymphocytes toward a Th2 anti-inflammatory profile in excessive inflammation
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