Analytical and numerical calculation of magnetic field distribution in the slotted air-gap of tangential surface permanent-magnet motors

This paper deals with the analytical and numerical analysis of the flux density distribution in the slotted air gap of permanent magnet motors with surface mounted tangentially magnetized permanent magnets. Two methods for magnetostatic field calculations are developed. The first one is an analytical method in which the effect of stator slots is taken into account by modulating the magnetic field distribution by the complex relative air gap permeance. The second one is a numerical method using 2-D finite element analysis with consideration of Dirichlet and anti-periodicity (periodicity) boundary conditions and Lagrange Multipliers for simulation of movement. The results obtained by the analytical method are compared to the results of finite-element analysis

Online Rotor Time Constant Estimator for Induction Machines with Optimum Flux

Non

Etude des Statuts de Stress et Anxio-Depressif Associés aux Troubles de Comportement Alimentaire chez des Etudiants en Première Année Académique à l’Université Félix Houphouët Boigny (Abidjan)

Description du sujet: Les troubles de comportement alimentaire (TCA) constituent un problème majeur de santé publique dont les facteurs de risque restent une énigme. Il y’a un manque d’informations sur la prévalence des TCA en Côte d’ivoire dans la population générale. Nous nous proposons dans cette présente étude d’évaluer la prévalence des TCA parmi un groupe d’étudiants en première année académique à l’Université Félix HOUPHOUËT BOIGNY, et essayer de connaître les possibles facteurs de risque. Methodologie: Nous avions soumis aux étudiants un questionnaire recueillant des déterminants socioéconomiques et démographiques, et les mesures anthropométriques ont été prises avec leur consentement. Les auto-questionnaires du EAT 26 et le BITE ont permis d’évaluer les prévalences du TCA anorexique et boulimique, respectivement. Enfin, l’état mental du Stress, d’Anxiété ou de Dépression diagnostiqué avec le questionnaire du DASS 21. Résultats: Nos résultats montrent essentiellement que 45,14% des étudiants souffrent du risque de TCA anorexique contre seulement 4,85% pour le TCA boulimique. Les sujets des deux sexes sont aussi bien affectés par le risque d’anorexie que par les TCA boulimique. La prévalence du stress, d’anxiété ou de dépression est très importante parmi les étudiants et étudiantes selon les réponses au DASS 21. Le test de khi-deux montre un lien hautement significatif entre l’état de maigreur et le risque de TCA anorexique (p<0,01). De plus, la relation entre les états mentaux de stress, d’anxiété et le risque de TCA anorexique est très significatif (p<0,001). Conclusion: Même si des études supplémentaires sont nécessaires, nos résultats appellent à une stratégie de prévention des TCA en milieu universitaire en recommandant un programme national de détection précoce et de prise en charge des étudiants victimes.   Background: Eating disorders (ED) are major health problem which risk factors remain unwell known. This is due to scarce of informations about the prevalence of ED in Ivorian general population. Here, we describe the prevalence of eating ED among first year students at Felix Houphouet Boigny university of Abidjan, Ivory Coast, and attempt to understand the possible risks factors involved. Methods: Students are submitted to a questionnaire including socioeconomic and demographic data, and anthropometric parameters recorded with their consent. A self-rating questionnaire of DASS 1 for the assessment of the psychological status as stress, anxiety and depression. The EAT 26 and BITE self-rating questionnaires used to evaluate the prevalence of the ED of anorexia and Bulimia, respectively. Results: Our results reported that 45,14% of students suffered from risk of anorexic eating disorders compared to only 4,85% for the bulimia. The female and students are both more affected as well as by anorexic and bulimia disorders. The levels of stress, anxiety and depression are significantly increased according to the DASS 21 responses analysis. Otherwise, the khi-deux analysis revealed high significant relation between emaciation status and anorexia disorders (p<0,01). The mental status of stress and anxiety are commonly found in anorexic students (p<0, 001). Conclusion: Some additional researches are need about current topic. However, our findings draw attention for the elaboration of a national program in order to early detection and take care of vulnerable students

Etude des Statuts de Stress et Anxio-Depressif Associés aux Troubles de Comportement Alimentaire chez des Etudiants en Première Année Académique à l’Université Félix Houphouët Boigny (Abidjan)

Description du sujet: Les troubles de comportement alimentaire (TCA) constituent un problème majeur de santé publique dont les facteurs de risque restent une énigme. Il y’a un manque d’informations sur la prévalence des TCA en Côte d’ivoire dans la population générale. Nous nous proposons dans cette présente étude d’évaluer la prévalence des TCA parmi un groupe d’étudiants en première année académique à l’Université Félix HOUPHOUËT BOIGNY, et essayer de connaître les possibles facteurs de risque. Methodologie: Nous avions soumis aux étudiants un questionnaire recueillant des déterminants socioéconomiques et démographiques, et les mesures anthropométriques ont été prises avec leur consentement. Les auto-questionnaires du EAT 26 et le BITE ont permis d’évaluer les prévalences du TCA anorexique et boulimique, respectivement. Enfin, l’état mental du Stress, d’Anxiété ou de Dépression diagnostiqué avec le questionnaire du DASS 21. Résultats: Nos résultats montrent essentiellement que 45,14% des étudiants souffrent du risque de TCA anorexique contre seulement 4,85% pour le TCA boulimique. Les sujets des deux sexes sont aussi bien affectés par le risque d’anorexie que par les TCA boulimique. La prévalence du stress, d’anxiété ou de dépression est très importante parmi les étudiants et étudiantes selon les réponses au DASS 21. Le test de khi-deux montre un lien hautement significatif entre l’état de maigreur et le risque de TCA anorexique (p<0,01). De plus, la relation entre les états mentaux de stress, d’anxiété et le risque de TCA anorexique est très significatif (p<0,001). Conclusion: Même si des études supplémentaires sont nécessaires, nos résultats appellent à une stratégie de prévention des TCA en milieu universitaire en recommandant un programme national de détection précoce et de prise en charge des étudiants victimes.   Background: Eating disorders (ED) are major health problem which risk factors remain unwell known. This is due to scarce of informations about the prevalence of ED in Ivorian general population. Here, we describe the prevalence of eating ED among first year students at Felix Houphouet Boigny university of Abidjan, Ivory Coast, and attempt to understand the possible risks factors involved. Methods: Students are submitted to a questionnaire including socioeconomic and demographic data, and anthropometric parameters recorded with their consent. A self-rating questionnaire of DASS 1 for the assessment of the psychological status as stress, anxiety and depression. The EAT 26 and BITE self-rating questionnaires used to evaluate the prevalence of the ED of anorexia and Bulimia, respectively. Results: Our results reported that 45,14% of students suffered from risk of anorexic eating disorders compared to only 4,85% for the bulimia. The female and students are both more affected as well as by anorexic and bulimia disorders. The levels of stress, anxiety and depression are significantly increased according to the DASS 21 responses analysis. Otherwise, the khi-deux analysis revealed high significant relation between emaciation status and anorexia disorders (p<0,01). The mental status of stress and anxiety are commonly found in anorexic students (p<0, 001). Conclusion: Some additional researches are need about current topic. However, our findings draw attention for the elaboration of a national program in order to early detection and take care of vulnerable students

Nutritional Status and School Achievements in a Rural Area of Anti-Atlas, Morocco

ABSTRAC

A collaborative model to implement flexible, accessible and efficient oncogenetic services for hereditary breast and ovarian cancer : the C-MOnGene study

Medical genetic services are facing an unprecedented demand for counseling and testing for hereditary breast and ovarian cancer (HBOC) in a context of limited resources. To help resolve this issue, a collaborative oncogenetic model was recently developed and implemented at the CHU de Québec-Université Laval; Quebec; Canada. Here, we present the protocol of the C-MOnGene (Collaborative Model in OncoGenetics) study, funded to examine the context in which the model was implemented and document the lessons that can be learned to optimize the delivery of oncogenetic services. Within three years of implementation, the model allowed researchers to double the annual number of patients seen in genetic counseling. The average number of days between genetic counseling and disclosure of test results significantly decreased. Group counseling sessions improved participants' understanding of breast cancer risk and increased knowledge of breast cancer and genetics and a large majority of them reported to be overwhelmingly satisfied with the process. These quality and performance indicators suggest this oncogenetic model offers a flexible, patient-centered and efficient genetic counseling and testing for HBOC. By identifying the critical facilitating factors and barriers, our study will provide an evidence base for organizations interested in transitioning to an oncogenetic model integrated into oncology care; including teams that are not specialized but are trained in genetics

Durvalumab Plus Carboplatin/Paclitaxel Followed by Maintenance Durvalumab With or Without Olaparib as First-Line Treatment for Advanced Endometrial Cancer: The Phase III DUO-E Trial

PURPOSE Immunotherapy and chemotherapy combinations have shown activity in endometrial cancer, with greater benefit in mismatch repair (MMR)-deficient (dMMR) than MMR-proficient (pMMR) disease. Adding a poly(ADP-ribose) polymerase inhibitor may improve outcomes, especially in pMMR disease. METHODS This phase III, global, double-blind, placebo-controlled trial randomly assigned eligible patients with newly diagnosed advanced or recurrent endometrial cancer 1:1:1 to: carboplatin/paclitaxel plus durvalumab placebo followed by placebo maintenance (control arm); carboplatin/paclitaxel plus durvalumab followed by maintenance durvalumab plus olaparib placebo (durvalumab arm); or carboplatin/paclitaxel plus durvalumab followed by maintenance durvalumab plus olaparib (durvalumab + olaparib arm). The primary end points were progression-free survival (PFS) in the durvalumab arm versus control and the durvalumab + olaparib arm versus control. RESULTS Seven hundred eighteen patients were randomly assigned. In the intention-to-treat population, statistically significant PFS benefit was observed in the durvalumab (hazard ratio [HR], 0.71 [95% CI, 0.57 to 0.89]; P = .003) and durvalumab + olaparib arms (HR, 0.55 [95% CI, 0.43 to 0.69]; P < .0001) versus control. Prespecified, exploratory subgroup analyses showed PFS benefit in dMMR (HR [durvalumab v control], 0.42 [95% CI, 0.22 to 0.80]; HR [durvalumab + olaparib v control], 0.41 [95% CI, 0.21 to 0.75]) and pMMR subgroups (HR [durvalumab v control], 0.77 [95% CI, 0.60 to 0.97]; HR [durvalumab + olaparib v control] 0.57; [95% CI, 0.44 to 0.73]); and in PD-L1-positive subgroups (HR [durvalumab v control], 0.63 [95% CI, 0.48 to 0.83]; HR [durvalumab + olaparib v control], 0.42 [95% CI, 0.31 to 0.57]). Interim overall survival results (maturity approximately 28%) were supportive of the primary outcomes (durvalumab v control: HR, 0.77 [95% CI, 0.56 to 1.07]; P = .120; durvalumab + olaparib v control: HR, 0.59 [95% CI, 0.42 to 0.83]; P = .003). The safety profiles of the experimental arms were generally consistent with individual agents. CONCLUSION Carboplatin/paclitaxel plus durvalumab followed by maintenance durvalumab with or without olaparib demonstrated a statistically significant and clinically meaningful PFS benefit in patients with advanced or recurrent endometrial cancer

Minimally Invasive Surgery for Cervical Cancer in Light of the LACC Trial: What Have We Learned?

Cervical cancer is the most common gynecologic malignancy and the fourth most common cancer in women worldwide. Over the last two decades, minimally invasive surgery (MIS) emerged as the mainstay in the surgical management of cervical cancer, bringing advantages such as lower operative morbidity and shorter hospital stay compared to open surgery while maintaining comparable oncologic outcomes in numerous retrospective studies. However, in 2018, a prospective phase III randomized controlled trial, &ldquo;Laparoscopic Approach to Carcinoma of the Cervix (LACC)&rdquo;, unexpectedly reported that MIS was associated with a statistically significant poorer overall survival and disease-free survival compared to open surgery in patients with early-stage cervical cancer. Various hypotheses have been raised by the authors to try to explain these results, but the LACC trial was not powered to answer those questions. In this study, through an exhaustive literature review, we wish to explore some of the potential causes that may explain the poorer oncologic outcomes associated with MIS, including the type of MIS surgery, the size of the lesion, the impact of CO2 pneumoperitoneum, prior conization, the use of uterine manipulator, the use of protective measures, and the effect of surgical expertise/learning curve