Catalogue of the library of the Tōkyō Teikoku-Daigaku (Imperial university of Tōkyō).

Comprises European books only.Contents.--pt. I. General. Alphabetico-classified.--pt. II. Jurisprudence, politics, finance, economics, statistics, sociology. Systematically arranged.Mode of access: Internet

Self-organizing Map Analysis for Understanding Comprehensive Relationships between Formulation Variables, State of Water, and the Physical Stability of Pharmaceutical Emulsions

The physical stability of pharmaceutical emulsions is an important quality attribute to be considered. To obtain a better understanding of this issue, this study investigated the contribution of the state of water to the physical stability of pharmaceutical emulsions. The key technology to evaluate the state of water was magnetic resonance imaging (MRI). For sample preparation, model emulsions with different formulation variables (surfactant content, water content, and hydrophilic–lipophilic balance) were prepared. The T1 relaxation time, diffusion coefficient, and viscosity were measured as physical properties. The physical stability of the samples was evaluated using apparent diffusion coefficient maps acquired by MRI. Data analysis of the observed data was performed using the nonlinear response surface method and Kohonen’s self-organizing map (SOM). It was determined that, depending on the formulation variables, the state of water was substantially changed and it played a significant role in the physical stability. SOM analysis successfully classified the conditions of formulation variables into four distinct clusters in terms of the similarity of the physical properties of the resultant emulsions, and then clarified the characteristics of the stable emulsions. This study provided us with a comprehensive understanding of the formulation variables, physical properties, and stability concerning the preparation of the model emulsion

Ashikaga Gakkō Kichōsho mokuroku.

Mode of access: Internet

Toshokan Dayori No.122

9月

Toshokan zasshi.

Mode of access: Internet.An author-title, and subject index covering 1907-1960 published separately in 1964.Latest issue consulted: Dai 101-kan dai 10-gō (2007-nen 10-gatsugō) = tsūkan 1007-gō.Description based on: Dai 26-gō, published in 1916; title from cover

Toshokan Dayori No.99

2011年2月/3月合併

Waseda Daigaku Toshokan Wa-Kan tosho bunrui mokuroku /

Sōrui no bu.Mode of access: Internet.A. L. holds v.3,5, 10 only