The Significance of Group Supervision to Yogo Teachers in Japan

This study aimed to evaluate the significance of group supervision to Yogo teachers in Japan, who often deal with work-related problems in isolation. Like school nurses in the United States, the role of the Yogo teacher is to oversee students’ health education and management. In this study, eight Yogo teachers, each with a minimum of six years’ experience, attended six supervised group sessions in 2016. During each session, one participant presented a case, and all participants then engaged in a general exchange of opinions about the case. Following the six sessions, semi-structured interviews were conducted with the participants, and the interview data were analyzed using M-GTA (modified grounded theory approach). The results generated 14 concepts and six categories, schematizing the Yogo teachers’ change of consciousness in relation to each category. The Yogo teachers evidenced needs in the categories of “Emotional Support,” “Awareness,” “Systemic Thinking,” “Collaboration,” “Motivation Improvement,” and “Training Location.” Ultimately, the study demonstrated that supervision by family therapists improved education by enhancing Yogo teachers’ consultation abilities and systemic thinking. Yogo teachers’ participation in the group supervision resulted in the following change in consciousness: their awareness was deepened by receiving emotional support, by training with the intent to learn, and by considering the significance of collaboration. Overall, teachers experienced an increase in self-motivation. The process for “Improvement of consultation ability” also became clear. Thus, group supervision by psychiatrists and/or family therapists has a positive impact on the overall motivation and work efficacy of Yogo teachers in Japan

"How is it Creative?” A Report on a Creative Workshop - Providing opportunities for hands-on learning to see things from a structural mechanics perspective -

P(論文)はままつクリエイティブシティブースター事業実行委員会が主催するクリエイティブワークショップの一つとして、建築構造に関するものを実施できないかという依頼を受け、それに応じて『しくみどうする？～なぜ段ボール箱に座るとつぶれてしまうのだろう？～』というワークショップの講師を2023年8月に務めた。小学生から中学生までを対象にして構造力学の視点からものを見ることを体験的に学んだ後に、段ボールを用いて椅子などを共同制作するワークショップを実施した。日頃の大学での授業においても計算モデルなどを示す前に、力学的なものの見方を伝えているので、その方法を援用する形でプログラムを検討した。学年の異なる受講者が同時に学べる内容にすることにかなり工夫を要した。本論文では、実施に当たっての検討過程、実施概要、受講者の反応について報告する。This workshop on architectural structures was conducted at the request of the Hamamatsu Creative City Star Project Executive Committee. In August 2023, I served as an instructor for a workshop entitled "How is it creative? ～Why do we get squashed when we sit in a cardboard box? ～” The workshop was designed for elementary and junior high school students to learn experientially how to look at things from the viewpoint of structural mechanics, and then to collaboratively create chairs and other items using cardboard. The program was designed to support the method used in daily university classes, where students are taught how to look at things from a mechanical viewpoint before calculation models are presented. It took a great deal of effort to design the program so that students of different grade levels could learn at the same time. This paper reports on the process of implementation, the outline of the program, and the reactions of the students.departmental bulletin pape

Robust Vehicle Detection under Various Environments to Realize Road Traffic Flow Surveillance Using an Infrared Thermal Camera

To realize road traffic flow surveillance under various environments which contain poor visibility conditions, we have already proposed two vehicle detection methods using thermal images taken with an infrared thermal camera. The first method uses pattern recognition for the windshields and their surroundings to detect vehicles. However, the first method decreases the vehicle detection accuracy in winter season. To maintain high vehicle detection accuracy in all seasons, we developed the second method. The second method uses tires’ thermal energy reflection areas on a road as the detection targets. The second method did not achieve high detection accuracy for vehicles on left-hand and right-hand lanes except for two center-lanes. Therefore, we have developed a new method based on the second method to increase the vehicle detection accuracy. This paper proposes the new method and shows that the detection accuracy for vehicles on all lanes is 92.1%. Therefore, by combining the first method and the new method, high vehicle detection accuracies are maintained under various environments, and road traffic flow surveillance can be realized

Functional promoter upstream p53 regulatory sequence of IGFBP3 that is silenced by tumor specific methylation

BACKGROUND: Insulin-like growth factor binding protein (IGFBP)-3 functions as a carrier of insulin-like growth factors (IGFs) in circulation and a mediator of the growth suppression signal in cells. There are two reported p53 regulatory regions in the IGFBP3 gene; one upstream of the promoter and one intronic. We previously reported a hot spot of promoter hypermethylation of IGFBP-3 in human hepatocellular carcinomas and derivative cell lines. As the hot spot locates at the putative upstream p53 consensus sequences, these p53 consensus sequences are really functional is a question to be answered. METHODS: In this study, we examined the p53 consensus sequences upstream of the IGFBP-3 promoter for the p53 induced expression of IGFBP-3. Deletion, mutagenesis, and methylation constructs of IGFBP-3 promoter were assessed in the human hepatoblastoma cell line HepG2 for promoter activity. RESULTS: Deletions and mutations of these sequences completely abolished the expression of IGFBP-3 in the presence of p53 overexpression. In vitro methylation of these p53 consensus sequences also suppressed IGFBP-3 expression. In contrast, the expression of IGFBP-3 was not affected in the absence of p53 overexpression. Further, we observed by electrophoresis mobility shift assay that p53 binding to the promoter region was diminished when methylated. CONCLUSION: From these observations, we conclude that four out of eleven p53 consensus sequences upstream of the IGFBP-3 promoter are essential for the p53 induced expression of IGFBP-3, and hypermethylation of these sequences selectively suppresses p53 induced IGFBP-3 expression in HepG2 cells

アクティブ ラーニング ノ バ ニ ヒツヨウナ ジョウケン - モクゾウ タイキュウヘキ ジャパンカップ ノ イギ -

学生が主体的に学ぶために有効な方法の一つとして、アクティブラーニングがある。本論では、木造耐力壁ジャパンカップの意義を振り返ることにより、アクティブラーニングの仕掛けとして活用できるイベントの必要条件として次の3つを提示した。1.実践的に取り組んだことへの成果が可視化されること2.個人の取り組みではなく、チームで取り組まざるを得ない要求がなされること3.ひとつの教育機関で閉じた形ではなく、社会と関わる機会が提供されていることI will review the significance of A Wooden Bearing Wall Japan Cup and present three necessary conditions to make an event having active learning. 1.Visibility of practical experiences 2.Request for team work 3. Openness that the activity is in our societ

ADAMTS13 gene deletion enhances plasma high-mobility group box1 elevation and neuroinflammation in brain ischemia-reperfusion injury

Highly adhesive glycoprotein von Willebrand factor (VWF) multimer induces platelet aggregation and leukocyte tethering or extravasation on the injured vascular wall, contributing to microvascular plugging and inflammation in brain ischemia-reperfusion. A disintegrin and metalloproteinase with thrombospondin type-1 motifs 13 (ADAMTS13) cleaves the VWF multimer strand and reduces its prothrombotic and proinflammatory functions. Although ADAMTS13 deficiency is known to amplify post-ischemic cerebral hypoperfusion, there is no report available on the effect of ADAMTS13 on inflammation after brain ischemia. We investigated if ADAMTS13 deficiency intensifies the increase of extracellular HMGB1, a hallmark of post-stroke inflammation, and exacerbates brain injury after ischemia-reperfusion. ADAMTS13 gene knockout (KO) and wild-type (WT) mice were subjected to 30-min middle cerebral artery occlusion (MCAO) and 23.5-h reperfusion under continuous monitoring of regional cerebral blood flow (rCBF). The infarct volume, plasma high-mobility group box1 (HMGB1) level, and immunoreactivity of the ischemic cerebral cortical tissue (double immunofluorescent labeling) against HMGB1/NeuN (neuron-specific nuclear protein) or HMGB1/MPO (myeloperoxidase) were estimated 24h after MCAO. ADAMTS13KO mice had larger brain infarcts compared with WT 24h after MCAO (p<0.05). The rCBF during reperfusion decreased more in ADAMTS13KO mice. The plasma HMGB1 increased more in ADAMTS13KO mice than in WT after ischemia-reperfusion (p<0.05). Brain ischemia induced more prominent activation of inflammatory cells co-expressing HMGB1 and MPO and more marked neuronal death in the cortical ischemic penumbra of ADAMTS13KO mice. ADAMTS13 deficiency may enhance systemic and brain inflammation associated with HMGB1 neurotoxicity, and aggravate brain damage in mice after brief focal ischemia. We hypothesize that ADAMTS13 protects brain from ischemia-reperfusion injury by regulating VWF-dependent inflammation as well as microvascular pluggin

Coulomb Dissociation of Halo Nuclei

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