Curiosity is a Key Factor to Awaken the Learner's Interest in Learning to Learn

La curiosidad factor clave en el aprender a aprender de los educandos, desde su capacidades cognitivas y recursos metodológicos. El objetivo es establecer los fundamentos de la curiosidad en congruencia con el aprender a aprender del alumnado. El proceso investigativo se basa en el enfoque mixto, el diseño no experimental, el tipo de investigación es bibliográfico y de campo. Se aplicó una encuesta a 29 docentes de educación básica media. La información resalta: el 93.10% (27 de 29) no les ha mencionado que la antesala de la curiosidad es el asombro; el 96.55% (28 de 29) carecen de información sobre las categorías de la curiosidad: perceptual y epistémica; el 96.55% (28 de 29) no existe ninguna exigencia para incluir las dimensiones de la curiosidad: dual, amplia y profunda; el 75.86% (22 de 29) tiene un conocimiento elemental sobre la condición básica de aprender a aprender y el 100% (29 de 29) explicitan que no los han capacitado en las dimensiones ni categorías de la curiosidad, a partir de los datos obtenidos se evidencia que los educadores presentan falencias en tópicos analizados, es pertinente formar a los docentes en la curiosidad y el aprender a aprender.Curiosity is a key factor in students' learning to learn, based on their cognitive abilities and methodological resources. The objective is to establish the foundations of curiosity in congruence with the students' learning to learn. The research process is based on the mixed approach, non-experimental design, the type of research is bibliographic and field. A survey was applied to 29 secondary basic education teachers. The information stands out: 93.10% (27 of 29) have not mentioned that the prelude to curiosity is amazement; 96.55% (28 of 29) lack information about the categories of curiosity: perceptual and epistemic; 96.55% (28 of 29) there is no requirement to include the dimensions of curiosity: dual, broad and deep; 75.86% (22 of 29) have elementary knowledge about the basic condition of learning to learn and 100% (29 of 29) explain that they have not been trained in the dimensions or categories of curiosity, based on the data obtained. It is evident that educators present shortcomings in the topics analyzed, it is pertinent to train teachers in curiosity and learning to learn

A chromosome-level genome assembly enables the identification of the follicule stimulating hormone receptor as the master sex-determining gene in the flatfish Solea senegalensis

Sex determination (SD) shows huge variation among fish and a high evolutionary rate, as illustrated by the Pleuronectiformes (flatfishes). This order is characterized by its adaptation to demersal life, compact genomes and diversity of SD mechanisms. Here, we assembled the Solea senegalensis genome, a flatfish of great commercial value, into 82 contigs (614 Mb) combining long- and short-read sequencing, which were next scaffolded using a highly dense genetic map (28,838 markers, 21 linkage groups), representing 98.9% of the assembly. Further, we established the correspondence between the assembly and the 21 chromosomes by using BAC-FISH. Whole genome resequencing of six males and six females enabled the identification of 41 single nucleotide polymorphism variants in the follicle stimulating hormone receptor (fshr) consistent with an XX/XY SD system. The observed sex association was validated in a broader independent sample, providing a novel molecular sexing tool. The fshr gene displayed differential expression between male and female gonads from 86 days post-fertilization, when the gonad is still an undifferentiated primordium, concomitant with the activation of amh and cyp19a1a, testis and ovary marker genes, respectively, in males and females. The Y-linked fshr allele, which included 24 nonsynonymous variants and showed a highly divergent 3D protein structure, was overexpressed in males compared to the X-linked allele at all stages of gonadal differentiation. We hypothesize a mechanism hampering the action of the follicle stimulating hormone driving the undifferentiated gonad toward testisEuropean Union's Horizon 2020 research and innovation programme under grant agreement (AQUA-FAANG). Grant Number: 81792. Junta de Andalucía-FEDER Grant. Grant Number: P20-00938. Spanish Ministry of Economy and Competitiveness, FEDER Grants. Grant Numbers: RTI2018-096847-B-C21, RTI2018-096847-B-C22S

A chromosome-level genome assembly enables the identification of the follicule stimulating hormone receptor as the master sex determining gene in the flatfish Solea senegalensis

Sex determination (SD) shows huge variation among fish and a high evolutionary rate, as illustrated by the Pleuronectiformes (flatfishes). This order is characterized by its adaptation to demersal life, compact genomes and diversity of SD mechanisms. Here, we assembled the Solea senegalensis genome, a flatfish of great commercial value, into 82 contigs (614 Mb) combining long- and short-read sequencing, which were next scaffolded using a highly dense genetic map (28,838 markers, 21 linkage groups), representing 98.9% of the assembly. Further, we established the correspondence between the assembly and the 21 chromosomes by using BAC-FISH. Whole genome resequencing of six males and six females enabled the identification of 41 SNP variants in the follicle stimulating hormone receptor (fshr) consistent with an XX / XY SD system. The observed sex association was validated in a broader independent sample, providing a novel molecular sexing tool. Fshr displayed differential gene expression between male and female gonads from 86 days post-fertilization, when the gonad is still an undifferentiated primordium, concomitant with the activation of amh and cyp19a1a, testis and ovary marker genes, respectively, in males and females. The Y-linked fshr allele, which included 24 non-synonymous variants and showed a highly divergent 3D protein structure, was overexpressed in males compared to the X-linked allele at all stages of gonadal differentiation. We hypothesize a mechanism hampering the action of the follicle stimulating hormone driving the undifferentiated gonad toward testis.info:eu-repo/semantics/acceptedVersio