Study of Mex(VO3)2 vanadates, (Me = Co, Ni, Mn, 1 < x < 2) for lithium rechargeable cells

Transition metal vanadates, Mex(VO3)2.2H2O, where Me = Co, Ni and Mn and 1.0 < x < 2.0, were found to reversibly insert lithium. The efficiency of reversible insertion depended on both the transition metal present and the stoichiometric ratio of Me:V in the vanadate structure. The Ni and Co vanadates gave the highest specific capacities using lithium metal coin cells, with initial specific capacities above 0.7 A h/g (1.0 W h/g) when x is near 1.0. The operating voltage of these materials was in the range of 1.0 to 2.0 V. Lithium ion coin cells using LiCoO2 coupled with the vanadates, were also examined. These were found to deliver about 200 mA h/g, with average voltages of 2.5 to 2.0 V for values of x from 1.1 to 1.2.Peer reviewed: YesNRC publication: Ye

Quality of Life, Wishes, and Needs in Women with Gestational Diabetes: Italian DAWN Pregnancy Study

The DAWN (Diabetes Attitudes, Wishes and Needs) study is a survey promoted by the International Diabetes Federation to recognize the perceptions and attitudes of people suffering from diabetes mellitus. In this context, we evaluated the quality of life of Italian and immigrant women with gestational diabetes mellitus (GDM). Information was gathered using a structured questionnaire for patients' self-compilation. In a 3-month period, a 51-item questionnaire was submitted to 198 Italians and 88 immigrants (from 27 different foreign nationalities). Italian women were older and had higher education than the immigrants. 60% of the Italians and 38% of the immigrants had a family history of diabetes mellitus. In both groups, the diagnosis of GDM caused anxiety; one-third of women feared their child could contract diabetes at delivery and/or have congenital malformations. Some women had trouble in following treatment regimens: the major concern being dietary advice and blood glucose testing. Most women were satisfied (34%) or highly satisfied (60%) with the quality of care, although the degree of cooperation between diabetes specialists and gynaecologists was considered sometimes unsatisfactory. In order to optimize maternal and foetal outcomes, educational projects and improved communication between patients and the healthcare provider team are recommended

Composition with Target Constraints

It is known that the composition of schema mappings, each specified by source-to-target tgds (st-tgds), can be specified by a second-order tgd (SO tgd). We consider the question of what happens when target constraints are allowed. Specifically, we consider the question of specifying the composition of standard schema mappings (those specified by st-tgds, target egds, and a weakly acyclic set of target tgds). We show that SO tgds, even with the assistance of arbitrary source constraints and target constraints, cannot specify in general the composition of two standard schema mappings. Therefore, we introduce source-to-target second-order dependencies (st-SO dependencies), which are similar to SO tgds, but allow equations in the conclusion. We show that st-SO dependencies (along with target egds and target tgds) are sufficient to express the composition of every finite sequence of standard schema mappings, and further, every st-SO dependency specifies such a composition. In addition to this expressive power, we show that st-SO dependencies enjoy other desirable properties. In particular, they have a polynomial-time chase that generates a universal solution. This universal solution can be used to find the certain answers to unions of conjunctive queries in polynomial time. It is easy to show that the composition of an arbitrary number of standard schema mappings is equivalent to the composition of only two standard schema mappings. We show that surprisingly, the analogous result holds also for schema mappings specified by just st-tgds (no target constraints). This is proven by showing that every SO tgd is equivalent to an unnested SO tgd (one where there is no nesting of function symbols). Similarly, we prove unnesting results for st-SO dependencies, with the same types of consequences.Comment: This paper is an extended version of: M. Arenas, R. Fagin, and A. Nash. Composition with Target Constraints. In 13th International Conference on Database Theory (ICDT), pages 129-142, 201

Public policies, law and bioethics: : a framework for producing public health policy across the European Union

Unlike the duties of clinicians to patients, professional standards for ethical practice are not well defined in public health. This is mainly due to public health practice having to reconcile tensions between public and private interest(s). This involves at times being paternalistic, while recognising the importance of privacy and autonomy, and at the same time balancing the interests of some against those of others. The Public Health specialist operates at the macro level, frequently having to infer the wishes and needs of individuals that make up a population and may have to make decisions where the interests of people conflict. This is problematic when devising policy for small populations; however, it becomes even more difficult when there is responsibility for many communities or nation states. Under the Treaty on European Union, the European Commission was given a competence in public health. Different cultures will give different moral weight to protecting individual interests versus action for collective benefit. However, even subtle differences in moral preferences may cause problems in deriving public health policy within the European Union. Understanding the extent to which different communities perceive issues such as social cohesion by facilitating cultural dialogues will be vital if European institutions are to work towards new forms of citizenship. The aim of EuroPHEN was to derive a framework for producing common approaches to public health policy across Europe. Little work has been done on integrating ethical analysis with empirical research, especially on trade-offs between private and public interests. The disciplines of philosophy and public policy have been weakly connected. Much of the thinking on public health ethics has hitherto been conducted in the United States of America, and an ethical framework for public health within Europe would need to reflect the greater respect for values such as solidarity and integrity which are more highly valued in Europe. Towards this aim EuroPHEN compared the organisation of public health structures and public policy responses to selected public health problems in Member States to examine how public policy in different countries weighs competing claims of private and public interest. Ethical analysis was performed of tensions between the private and public interest in the context of various ethical theories, principles and traditions. During autumn 2003, 96 focus groups were held across 16 European Union Member States exploring public attitudes and values to public versus private interests. The groups were constructed to allow examination of differences in attitudes between countries and demographic groups (age, gender, smoking status, educational level and parental and marital status). Focus group participants discussed issues such as attitudes to community; funding of public services; rights and responsibilities of citizens; rules and regulations; compulsory car seat belts; policies to reduce tobacco consumption; Not-In-My-Back-Yard arguments; banning of smacking of children; legalising cannabis and parental choice with regards to immunisation. This project proposes a preliminary framework and stresses that a European policy of Public Health will have to adopt a complex, pluralistic and dynamic goal structure, capable of accommodating variations in what specific goals should be prioritised in the specific socio-economic settings of individual countries

The risk stratification of adverse neonatal outcomes in women with gestational diabetes (STRONG) study

Aims: To assess the risk of adverse neonatal outcomes in women with gestational diabetes (GDM) by identifying subgroups of women at higher risk to recognize the characteristics most associated with an excess of risk. Methods: Observational, retrospective, multicenter study involving consecutive women with GDM. To identify distinct and homogeneous subgroups of women at a higher risk, the RECursive Partitioning and AMalgamation (RECPAM) method was used. Overall, 2736 pregnancies complicated by GDM were analyzed. The main outcome measure was the occurrence of adverse neonatal outcomes in pregnancies complicated by GDM. Results: Among study participants (median age 36.8 years, pre-gestational BMI 24.8 kg/m2), six miscarriages, one neonatal death, but no maternal death was recorded. The occurrence of the cumulative adverse outcome (OR 2.48, 95% CI 1.59–3.87), large for gestational age (OR 3.99, 95% CI 2.40–6.63), fetal malformation (OR 2.66, 95% CI 1.00–7.18), and respiratory distress (OR 4.33, 95% CI 1.33–14.12) was associated with previous macrosomia. Large for gestational age was also associated with obesity (OR 1.46, 95% CI 1.00–2.15). Small for gestational age was associated with first trimester glucose levels (OR 1.96, 95% CI 1.04–3.69). Neonatal hypoglycemia was associated with overweight (OR 1.52, 95% CI 1.02–2.27) and obesity (OR 1.62, 95% CI 1.04–2.51). The RECPAM analysis identified high-risk subgroups mainly characterized by high pre-pregnancy BMI (OR 1.68, 95% CI 1.21–2.33 for obese; OR 1.38 95% CI 1.03–1.87 for overweight). Conclusions: A deep investigation on the factors associated with adverse neonatal outcomes requires a risk stratification. In particular, great attention must be paid to the prevention and treatment of obesity

methods and tools for the development of adaptive applications

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Quality of life and treatment satisfaction in adults with Type 1 diabetes: A comparison between continuous subcutaneous insulin infusion and multiple daily injections

Aims: The aim of this case-control study was to compare quality of life (QoL) and treatment satisfaction in adults with Type 1 diabetes (T1DM) treated with either continuous subcutaneous insulin infusion (CSII) or multiple daily injections (MDI). Methods: Consecutive patients aged between 18 and 55 years, and attending diabetes clinics for a routine visit, completed the Diabetes-Specific Quality-of-Life Scale (DSQOLS), the Diabetes Treatment Satisfaction Questionnaire (DTSQ) and the SF-36 Health Survey (SF-36). Case (CSII) and control subjects (MDI) were recruited in a 1 : 2 ratio. Results: Overall, 1341 individuals were enrolled by 62 diabetes clinics; 481 were cases and 860 control subjects. Cases had a longer diabetes duration and were more likely to have eye and renal complications. Age, school education, occupation and HbA1c were similar. Of control subjects, 90% followed glargine-based MDI regimens and 10% used NPH-based MDI regimens. On multivariate analysis, after adjusting for socioeconomic and clinical characteristics, scores in the following areas of the DSQOLS were higher in cases than control subjects: diet restrictions (β = 5.96; P &lt; 0.0001), daily hassles (β = 3.57; P = 0.01) and fears about hypoglycaemia (β = 3.88; P = 0.006). Treatment with CSII was also associated with a markedly higher DTSQ score (β = 4.13; P &lt; 0.0001) compared with MDI. Results were similar when CSII was compared separately with glargine- or NPH-based MDI regimens. Conclusions: This large, non-randomized, case-control study suggests quality of life gains deriving from greater lifestyle flexibility, less fear of hypoglycaemia, and higher treatment satisfaction, when CSII is compared with either glargine-based or NPH-based MDI regimens. © 2008 The Authors

reference architecture and framework

M. Adorni, F. Arcelli, S. Bandini, L. Baresi, C. Batini, A. Bianchi, D. Bianchini, M. Brioschi, A. Caforio, A. Cali, P. Cappellari, C. Cappiello, T. Catarci, A. Corallo, V. De Antonellis, C. Franza, G. Giunta, A. Limonta, G. Lorenzo, P. Losi, A. Maurino, M. Melideo, D. Micucci, S. Modafferi, E. Mussi, L. Negri, C. Pandolfo, B. Pernici, P. Plebani, D. Ragazzi, C. Raibulet, M. Riva, N. Simeoni, C. Simone, G. Solazzo, F. Tisato, R. Torlone, G. Vizzari, and A. Zill