The effect of zinc sulphate syrup on children's respiratory tract infections

BACKGROUND AND OBJECTIVE: After Iron, zinc is the second most abundant trace element in the body that is present in all organs, tissues and body fluids. It is a necessary component for maintaining immunological integrity antioxidant activity, and has critical role in the control and prevention of infection. The aim of this study was to investigate the effect of zinc sulphate syrup in treatment of children with respiratory tract infection. METHODS: In this randomized clinical trial study, one hundred and twenty four children with respiratory infection (62 in case and 62 in control group) from pediatric ward of Hajar hospital of Sharekord university enrolled. Both groups received standard treatment. In addition to, zinc sulphate syrup was given to case group and placebo to control group. Respiratory rate, bed and cough and fever duration were compared between the case and control groups (IRCT: 201103025951N1). FINDINGS: The mean duration of fever in the case group was 2.6±0.82 days and in the control group 4±1.5 days (p<0.001). The mean of bed duration in the case group was 4.7±1.5 days and in the control group 5±1.8 days (p=0.42). The mean of cough duration in the case and control groups was 3.4±1.3 and 4.7±1.6 days respectively (p=0.09). Respiratory rate in the case group was 28.3±4.3 and in the control 28.1±4.9 (p=0.77). CONCLUSION: The study showed that zinc supplementation has a beneficial effect in decreasing the fever duration in children with respiratory infection. But there was no significant effect on respiratory rate, duration of bed and cough

Brazilian disk tests: Circular holes and size effects

Abstract Size effects related to circular notched samples imply that the strength of the structure decreases as the hole radius increases. In this framework, Brazilian disk tests are carried out on brittle samples containing a circular hole. By considering two different polymers, namely Polymethyl-methacrylate (PMMA) and General-purpose Polystyrene (GPPS), respectively, five different notch radii were machined and tested for each material, keeping low the hole to disk diameter ratio in order to reproduce an infinite geometry. Under this assumption, analytical relationship for the stress field and the stress intensity factor can be implemented without loss of accuracy. The coupled finite fracture mechanics (FFM) is then applied to catch the recorded failure stresses, allowing a complete description of the experimental size effects. On the contrary, the smallest radius leads to a locally negative geometry, opening the discussion on the stability of crack propagation in circularly notched plates under generic biaxial loadings

Using the equivalent material concept and the average strain energy density to analyse the fracture behaviour of structural materials

ABSTRACT: This paper provides a complete overview of the applicability of the Equivalent Material Concept in conjunction with the Average Strain Energy Density criterion, to provide predictions of fracture loads in structural materials containing U-notches. The Average Strain Density Criterion (ASED) has a linear-elastic nature, so in principle, it does not provide satisfactory predictions of fracture loads in those materials with nonlinear behaviour. However, the Equivalent Material Concept (EMC) is able to transform a physically nonlinear material into an equivalent linear-elastic one and, therefore, the combination of the ASED criterion with the EMC (EMC?ASED criterion) should provide good predictions of fracture loads in physically nonlinear materials. The EMC?ASED criterion is here applied to different types of materials (polymers, composites and metals) with different grades of nonlinearity, showing the accuracy of the corresponding fracture load predictions and revealing qualitatively the limitations of the methodology. It is shown how the EMC?ASED criterion provides good predictions of fracture loads in nonlinear materials as long as the nonlinear behaviour is mainly limited to the tensile behaviour, and how the accuracy decreases when the nonlinear behaviour is extended to the material behaviour in the presence of defectsFunding: This research was funded by the Spanish Ministry of Science, Innovation and Universities, grant number PGC2018-095400-B-I00 (MCIU/AEI/FEDER, UE)

Water management for sustainable irrigated agriculture in the Zayandeh Rud Basin, Esfahan Province, Iran

Irrigation systemsCropping systemsIrrigated farmingRiver basinsTopographyGeomorphologyClimateHydrologyWater qualityGroundwaterSoil salinitySustainable agricultureIranEsfahan ProvinceZayandeh Rud BasinChadegan Reservoir

Classical and delayed orthostatic hypotension in patients with unexplained syncope and severe orthostatic intolerance

Background: Orthostatic hypotension (OH) is a major sign of cardiovascular autonomic failure leading to orthostatic intolerance and syncope. Orthostatic hypotension is traditionally divided into classical OH (cOH) and delayed OH (dOH), but the differences between the two variants are not well-studied. We performed a systematic clinical and neuroendocrine characterization of OH patients in a tertiary syncope unit. Methods: Among 2,167 consecutive patients (1,316 women, 60.7%; age, 52.6 ± 21.0 years) evaluated for unexplained syncope and severe orthostatic intolerance with standardized cardiovascular autonomic tests including head-up tilt (HUT), we identified those with a definitive diagnosis of cOH and dOH. We analyzed patients' history, clinical characteristics, hemodynamic variables, and plasma levels of epinephrine, norepinephrine, C-terminal-pro-arginine-vasopressin (CT-proAVP), C-terminal-endothelin-1, mid-regional-fragment of pro-atrial-natriuretic-peptide and pro-adrenomedullin in the supine position and at 3-min HUT. Results: We identified 248 cOH and 336 dOH patients (27% of the entire cohort); 111 cOH and 152 dOH had blood samples collected in the supine position and at 3-min HUT. Compared with dOH, cOH patients were older (68 vs. 60 years, p < 0.001), more often male (56.9 vs. 39.6%, p < 0.001), had higher systolic blood pressure (141 vs. 137 mmHg, p = 0.05), had lower estimated glomerular filtration rate (73 vs. 80 ml/min/1.73 m2, p = 0.003), more often pathologic Valsalva maneuver (86 vs. 49 patients, p < 0.001), pacemaker-treated arrhythmia (5 vs. 2%, p = 0.04), Parkinson's disease (5 vs. 1%, p = 0.008) and reported less palpitations before syncope (16 vs. 29%, p = 0.001). Supine and standing levels of CT-proAVP were higher in cOH (p = 0.022 and p < 0.001, respectively), whereas standing norepinephrine was higher in dOH (p = 0.001). After 3-min HUT, increases in epinephrine (p < 0.001) and CT-proAVP (p = 0.001) were greater in cOH, whereas norepinephrine increased more in dOH (p = 0.045). Conclusions: One-quarter of patients with unexplained syncope and severe orthostatic intolerance present orthostatic hypotension. Classical OH patients are older, more often have supine hypertension, pathologic Valsalva maneuver, Parkinson's disease, pacemaker-treated arrhythmia, and lower glomerular filtration rate. Classical OH is associated with increased vasopressin and epinephrine during HUT, but blunted increase in norepinephrine

Investigating the Security of EV Charging Mobile Applications As an Attack Surface

The adoption rate of EVs has witnessed a significant increase in recent years driven by multiple factors, chief among which is the increased flexibility and ease of access to charging infrastructure. To improve user experience, increase system flexibility and commercialize the charging process, mobile applications have been incorporated into the EV charging ecosystem. EV charging mobile applications allow consumers to remotely trigger actions on charging stations and use functionalities such as start/stop charging sessions, pay for usage, and locate charging stations, to name a few. In this paper, we study the security posture of the EV charging ecosystem against remote attacks, which exploit the insecurity of the EV charging mobile applications as an attack surface. We leverage a combination of static and dynamic analysis techniques to analyze the security of widely used EV charging mobile applications. Our analysis of 31 widely used mobile applications and their interactions with various components such as the cloud management systems indicate the lack of user/vehicle verification and improper authorization for critical functions, which lead to remote (dis)charging session hijacking and Denial of Service (DoS) attacks against the EV charging station. Indeed, we discuss specific remote attack scenarios and their impact on the EV users. More importantly, our analysis results demonstrate the feasibility of leveraging existing vulnerabilities across various EV charging mobile applications to perform wide-scale coordinated remote charging/discharging attacks against the connected critical infrastructure (e.g., power grid), with significant undesired economical and operational implications. Finally, we propose counter measures to secure the infrastructure and impede adversaries from performing reconnaissance and launching remote attacks using compromised accounts

Reliability and Performance Analysis of a Fault Tolerant Data Handling Protocol for Aerospace Applications

Data communication inside the satellite is one of the most important factors in satellite design. For this purpose, a variety of protocols have been developed in recent years. Controller Area Network (CAN) is one of the well-developed protocols to be used in the On-Board Data Handling (OBDH) systems for communication and geosynchronous satellites. Nonetheless, for aerospace applications which demand radiation hardened integrated circuits, a full featured stand-alone Rad-Hard CAN controller is unavailable. HDL (Hardware Description Language) based IP(Intellectual Property) Cores which are widely developed to be implemented on Rad-Hard FPGAs are more attractive. This paper proposes a novel fault tolerant CAN controller based on FPGAs to provide on-board data handling requirements of the communication satellites. We outline some practical topologies and discuss their complexities and reliability. Despite the fact that the most famous methods like TMR (Triple Modular Redundancy), are very common among designers, the reliability analyses show that these methods are unable to tolerate single upsets in routing matrixes. This paper proposes a robust data bus controller based on dual duplex redundancy on FPGAs. The fault injection experiments reveal that the proposed approach represents better performance respective to the conventional hardware redundancy. Furthermore, the experiments show that the capability of tolerating SEU effects by the proposed method is increased up to 7.17 times with respect to a regular design. The proposed architecture imposes 16.26% and 5.2% overhead in the required resources and the operating frequency in comparison to the regular TMR method

Berry effect in acoustical polarization transport in phononic crystals

We derive the semiclassical equations of motion of a transverse acoustical wave packet propagating in a phononic crystal subject to slowly varying perturbations. The formalism gives rise to Berry effect terms in the equations of motion, manifested as the Rytov polarization rotation law and the polarization-dependent Hall effect. We show that the formalism is also applicable to the case of non-periodic inhomogeneous media, yielding explicit expressions for the Berry effect terms.Comment: To appear in JETP Let