990 research outputs found

    O cultivo da beterraba para produção de álcool ou forragem na região sul do Brasil.

    Get PDF
    bitstream/item/119392/1/FOL-06037.pd

    Boc-Protection on L-DOPA: an Easy Way to Promote Underwater Adhesion

    Get PDF
    The ability of mussels to adhere to underwater surfaces has attracted a lot of attention from the scientific community. As proteins containing L-DOPA (3,4-dihydroxyphenyl-l-alanine) are involved in their adhesion, a common strategy to synthesize adhesives is the incorporation of this amino acid into other compounds. Herein, we report a study on four compounds of the family of Bocx-(L-DOPA)n-OMe (x = 1–3; n = 1,2), that we prepared through simple synthetic steps. Three of them showed the capability of underwater adhesion: while they are not adhesive in the dry phase, the adhesiveness is triggered when the dried sample is immersed in water or any aqueous solutions. The introduction of protecting groups stabilizes L-DOPA, preventing the oxidation of the catechol moiety, and enhances the hydrophobicity, helping the removal of water from the surface to bind. These molecules show good adhesiveness, with different properties, so they may be all used as adhesives for different purposes. These outcomes pave the way for new applications for these materials as green and biocompatible adhesives

    Respostas a tecnologias de trigo nos anos de 1981 e 1982.

    Get PDF
    bitstream/item/119404/1/FOL-06027.pd

    Ballast flight under high-speed trains: Wind tunnel full-scale experimental tests

    Get PDF
    The flying ballast phenomenon has become an important problem, in the last years, because of the development of high speed trains and the consequent increase of the speed up to 350. km/h. The problem is very complex since it is related to both railway infrastructure and train characteristics and since it involves mechanical and aerodynamic effects. The results of an experimental study carried out on the Italian high-speed railway and on a 1:1 real stretch of the railways in wind tunnel are presented in the paper. The study was aimed to analyze the effects of the height of the ballast level, the stone shape in the upper layer of the ballast and the compaction of the ballast bed on the problem. To this purpose a specific wind tunnel test rig was designed to reproduce in the wind tunnel a flow with the same average characteristics of the one measured on the real line, especially in the region close to the ballast and sleepers. Finally, starting from the results of these tests, possible countermeasures to ballast lifting on-set are proposed

    Diffuse Hemorrhagic Brain Metastases in an ALK Fusion Positive Patient on Crizotinib

    Get PDF

    Diversificação de culturas de inverno na região tritícola do sul do Brasil.

    Get PDF
    bitstream/item/126336/1/ID-7719.pdf2. ed. rev

    Rentabilidade fisica e econômica de inseticidas para pulgões safra de trigo de 1977.

    Get PDF
    bitstream/item/84146/1/CNPT-COM.-TEC.-1-77.pd

    In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as \u3b2-turn inducers

    Get PDF
    Small and easy-to-do mimetics of \u3b2-turns are of great interest to interfere with protein-protein recognition events mediated by \u3b2-turn recognition motifs. We propose a straightforward procedure for constraining the conformation of tetrapeptides lacking a pre-formed scaffold. According to the stereochemistry array, N-Ts tetrapeptides including Thr or PhSer (phenylserine) at the positions 2 or 3 gave rise in a single step to the sequences Oxd 2-Oxd3 or \u394Abu2-Oxd3 (Oxd, oxazolidin-2-one; \u394Abu, 2,3-dehydro-2-aminobutyric). These pseudo-Pro residues displayed highly constrained, and \u3c7 dihedral angles, and induced clear \u3b2-turns or inverse turns of type I or II, as determined by extensive spectroscopic and computational analyses. \ua9 The Royal Society of Chemistry 2013
    • …
    corecore