AMREF’s Stand Up For African Mothers Campaign: Training Midwives to Reduce Maternal Mortality in Africa

AMREF is the African Medical and Research Foundation, a uniquely African organization, created in 1957 which runs 145 health programmes a year to help around 7 million people in Africa. Headquartered in Nairobi and with offices around the world, AMREF ensures access to health care for the most vulnerable and marginalized people in Africa, with a focus on women and children. AMREF works within the communities, and works with and for women as they are the heart of the communities. Indeed, by focusing on midwives training in the Stand Up For African Mothers campaign, AMREF is able to talk about the key role of women and mothers for a healthy Africa and the needs of health workers to reduce mortality rates for mothers but also for children.AMREF ou African Medical and Research Foundation, est la première ONG africaine créée en 1957 qui gère 100 programmes de santé chaque année pour venir en aide à presque 7 millions de personnes en Afrique. Basée à Nairobi et avec des bureaux ouverts dans le monde entier, AMREF assure l’accés aux soins médicaux  pour les personnes les plus vulnérables et marginalisées d’Afrique, avec une attention plus particulière pour les femmes et les enfants. AMREF travaille au sein des communautés, avec et pour les femmes qui en sont le coeur. Ainsi, en se focalisant sur la formation des sages-femmes avec la campagne «Stand Up For African Mothers», AMREF est capable de parler du rôle-clef des femmes et des mères pour une Afrique en bonne santé mais aussi des besoins en personnel de santé pour réduire le taux de mortalité aussi bien chez les mères que chez leurs enfants.A 54 años de su creación, AMREF Flying Doctors, 1a ONG africana de salud pública, actúa en todos los ámbitos de la salud pública. La organización trabaja en particular a favor de la salud de las mujeres, de las madres y de sus niños, porque es inaceptable que mueran todavía cerca de 200.000 mujeres africanas cada año durante el embarazo o el parto, y que un millón y medio de niños queden huérfanos. Así, para reducir la mortalidad materna e infantil, AMREF defiende un proyecto ambicioso dentro del marco de los Objetivos del Milenio (OMD): el de capacitar a 15.000 parteras de aquí a 2015. En este artículo se habla del ejemplo de la formación de parteras en el Sudán Meridional, flamante estado africano. Se trata de una formación con presencia física, pero AMREF también capacita a distancia a miles de enfermeras y parteras a través de eLearning (por ejemplo, el programa de formación de 10.000 parteras en Uganda en 2010-2013)

AMREF’s Stand Up For African Mothers Campaign: Training Midwives to Reduce Maternal Mortality in Africa

AMREF is the African Medical and Research Foundation, a uniquely African organization, created in 1957 which runs 145 health programmes a year to help around 7 million people in Africa. Headquartered in Nairobi and with offices around the world, AMREF ensures access to health care for the most vulnerable and marginalized people in Africa, with a focus on women and children. AMREF works within the communities, and works with and for women as they are the heart of the communities. Indeed, by focusing on midwives training in the Stand Up For African Mothers campaign, AMREF is able to talk about the key role of women and mothers for a healthy Africa and the needs of health workers to reduce mortality rates for mothers but also for children.AMREF ou African Medical and Research Foundation, est la première ONG africaine créée en 1957 qui gère 100 programmes de santé chaque année pour venir en aide à presque 7 millions de personnes en Afrique. Basée à Nairobi et avec des bureaux ouverts dans le monde entier, AMREF assure l’accés aux soins médicaux  pour les personnes les plus vulnérables et marginalisées d’Afrique, avec une attention plus particulière pour les femmes et les enfants. AMREF travaille au sein des communautés, avec et pour les femmes qui en sont le coeur. Ainsi, en se focalisant sur la formation des sages-femmes avec la campagne «Stand Up For African Mothers», AMREF est capable de parler du rôle-clef des femmes et des mères pour une Afrique en bonne santé mais aussi des besoins en personnel de santé pour réduire le taux de mortalité aussi bien chez les mères que chez leurs enfants.A 54 años de su creación, AMREF Flying Doctors, 1a ONG africana de salud pública, actúa en todos los ámbitos de la salud pública. La organización trabaja en particular a favor de la salud de las mujeres, de las madres y de sus niños, porque es inaceptable que mueran todavía cerca de 200.000 mujeres africanas cada año durante el embarazo o el parto, y que un millón y medio de niños queden huérfanos. Así, para reducir la mortalidad materna e infantil, AMREF defiende un proyecto ambicioso dentro del marco de los Objetivos del Milenio (OMD): el de capacitar a 15.000 parteras de aquí a 2015. En este artículo se habla del ejemplo de la formación de parteras en el Sudán Meridional, flamante estado africano. Se trata de una formación con presencia física, pero AMREF también capacita a distancia a miles de enfermeras y parteras a través de eLearning (por ejemplo, el programa de formación de 10.000 parteras en Uganda en 2010-2013)

AMREF’s Stand Up For African Mothers Campaign: Training Midwives to Reduce Maternal Mortality in Africa

AMREF is the African Medical and Research Foundation, a uniquely African organization, created in 1957 which runs 145 health programmes a year to help around 7 million people in Africa. Headquartered in Nairobi and with offices around the world, AMREF ensures access to health care for the most vulnerable and marginalized people in Africa, with a focus on women and children. AMREF works within the communities, and works with and for women as they are the heart of the communities. Indeed, by focusing on midwives training in the Stand Up For African Mothers campaign, AMREF is able to talk about the key role of women and mothers for a healthy Africa and the needs of health workers to reduce mortality rates for mothers but also for children.AMREF ou African Medical and Research Foundation, est la première ONG africaine créée en 1957 qui gère 100 programmes de santé chaque année pour venir en aide à presque 7 millions de personnes en Afrique. Basée à Nairobi et avec des bureaux ouverts dans le monde entier, AMREF assure l’accés aux soins médicaux  pour les personnes les plus vulnérables et marginalisées d’Afrique, avec une attention plus particulière pour les femmes et les enfants. AMREF travaille au sein des communautés, avec et pour les femmes qui en sont le coeur. Ainsi, en se focalisant sur la formation des sages-femmes avec la campagne «Stand Up For African Mothers», AMREF est capable de parler du rôle-clef des femmes et des mères pour une Afrique en bonne santé mais aussi des besoins en personnel de santé pour réduire le taux de mortalité aussi bien chez les mères que chez leurs enfants.A 54 años de su creación, AMREF Flying Doctors, 1a ONG africana de salud pública, actúa en todos los ámbitos de la salud pública. La organización trabaja en particular a favor de la salud de las mujeres, de las madres y de sus niños, porque es inaceptable que mueran todavía cerca de 200.000 mujeres africanas cada año durante el embarazo o el parto, y que un millón y medio de niños queden huérfanos. Así, para reducir la mortalidad materna e infantil, AMREF defiende un proyecto ambicioso dentro del marco de los Objetivos del Milenio (OMD): el de capacitar a 15.000 parteras de aquí a 2015. En este artículo se habla del ejemplo de la formación de parteras en el Sudán Meridional, flamante estado africano. Se trata de una formación con presencia física, pero AMREF también capacita a distancia a miles de enfermeras y parteras a través de eLearning (por ejemplo, el programa de formación de 10.000 parteras en Uganda en 2010-2013)

Clinical variability at the mild end of BRAT1‐related spectrum: Evidence from two families with genotype–phenotype discordance

Biallelic mutations in the BRAT1 gene, encoding BRCA1-associated ATM activator 1, result in variable phenotypes, from rigidity and multifocal seizure syndrome, lethal neonatal to neurodevelopmental disorder, and cerebellar atrophy with or without seizures, without obvious genotype-phenotype associations. We describe two families at the mildest end of the spectrum, differing in clinical presentation despite a common genotype at the BRAT1 locus. Two siblings displayed nonprogressive congenital ataxia and shrunken cerebellum on magnetic resonance imaging. A third unrelated patient showed normal neurodevelopment, adolescence-onset seizures, and ataxia, shrunken cerebellum, and ultrastructural abnormalities on skin biopsy, representing the mildest form of NEDCAS hitherto described. Exome sequencing identified the c.638dup and the novel c.1395G>A BRAT1 variants, the latter causing exon 10 skippings. The p53-MCL test revealed normal ATM kinase activity. Our findings broaden the allelic and clinical spectrum of BRAT1-related disease, which should be suspected in presence of nonprogressive cerebellar signs, even without a neurodevelopmental disorder

AMREF’s Stand Up For African Mothers Campaign: Training Midwives to Reduce Maternal Mortality in Africa

AMREF is the African Medical and Research Foundation, a uniquely African organization, created in 1957 which runs 145 health programmes a year to help around 7 million people in Africa. Headquartered in Nairobi and with offices around the world, AMREF ensures access to health care for the most vulnerable and marginalized people in Africa, with a focus on women and children. AMREF works within the communities, and works with and for women as they are the heart of the communities. Indeed, by focusing on midwives training in the Stand Up For African Mothers campaign, AMREF is able to talk about the key role of women and mothers for a healthy Africa and the needs of health workers to reduce mortality rates for mothers but also for children

Urine sepiapterin excretion as a new diagnostic marker for sepiapterin reductase deficiency

Sepiapterin reductase deficiency (SRD) causes depletion of biogenic amines in the brain, early onset motor disorder, and intellectual disability. The diagnosticmarker for this rare disease is increased sepiapterin and biopterin in CSF. Through a new analytic methodology we demonstrated accumulation of sepiapterin in urine of four SRD patients several times greater than that found in healthy controls and carriers, regardless of age or treatment. Our findings suggest a newinterpretation of current theories of peripheral pterinmetabolismand provide a newnoninvasive diagnostic tool for children with early onset cryptogenetic developmental delay and/or movement disorder

Urine sepiapterin excretion as a new diagnostic marker for sepiapterin reductase deficiency

Sepiapterin reductase deficiency (SRD) causes depletion of biogenic amines in the brain, early onset motor disorder, and intellectual disability. The diagnosticmarker for this rare disease is increased sepiapterin and biopterin in CSF. Through a new analytic methodology we demonstrated accumulation of sepiapterin in urine of four SRD patients several times greater than that found in healthy controls and carriers, regardless of age or treatment. Our findings suggest a newinterpretation of current theories of peripheral pterinmetabolismand provide a newnoninvasive diagnostic tool for children with early onset cryptogenetic developmental delay and/or movement disorder

Impact of diet supplemented with microencapsulated condensed tannins on cow milk nutritional profile

Feed production systems should consider more sustainable solutions to reduce the pressure on earth's finite resources. In this work, we investigated the effect of microencapsulated condensed tannins (MCTs)-enhanced diet on the cow milk characteristics. The diet reduced the urea content, while preserved and the n-3 and n-6 portion of fatty acids. Aside from the rising of vitamin C level, MCTs had a negative effect on the amount of B group vitamins. MCTs may be considered a promising feed supplement that offers a good trade-off in terms of milk chemical quality while increasing the environmental sustainability of cattle livestock