Master Buddha & the jolly golly fun time gang.

This thesis is the first two chapters of a novel. The novel parodies the capitalist and consumerist United States of the 21st Century in the tradition of Thomas Pynchon, Kurt Vonnegut, and Donald Barthelme

Evolving Practices in Art Education

More than 100 years ago, university-dominated educational commissions began ascribing a priority to school subjects in primary and secondary education. In defining the roles and purposes of the modern secondary school, educators struggled with how best to determine the relative importance of individual school subjects. In 1894, Harvard president Charles Eliot led the Committee of Ten on Secondary School Studies, established by the NEA to recommend that all secondary school students study a common curriculum focusing on sciences, history, reading, writing and arithmetic. Art and music were eventually placed in positions of curricular inferiority

GNSS Signal Authentication via Power and Distortion Monitoring

We propose a simple low-cost technique that enables civil Global Positioning System (GPS) receivers and other civil global navigation satellite system (GNSS) receivers to reliably detect carry-off spoofing and jamming. The technique, which we call the Power-Distortion detector, classifies received signals as interference-free, multipath-afflicted, spoofed, or jammed according to observations of received power and correlatio n function distortion. It does not depend on external hardware or a network connection and can be readily implemented on many receivers via a firmware update. Crucially, the detector can with high probability distinguish low-power spoofing from ordinary multipath. In testing against over 25 high-quality empirical data sets yielding over 900,000 separate detection tests, the detector correctly alarms on all malicious spoofing or jamming attack s while maintaining a <0.5% single-channel false alarm rate.Aerospace Engineering and Engineering Mechanic

NASA's Astromaterials Database: Enabling Research Through Increased Access to Sample Data, Metadata and Imagery

The Astromaterials Acquisition & Curation Office at NASA's Johnson Space Center (JSC) is the designated facility for curating all of NASA's extraterrestrial samples. Today, the suite of collections includes the lunar samples from the Apollo missions, cosmic dust particles falling into the Earth's atmosphere, meteorites collected in Antarctica, comet and interstellar dust particles from the Stardust mission, asteroid particles from Japan's Hayabusa mission, solar wind atoms collected during the Genesis mission, and spaceexposed hardware from several missions. To support planetary science research on these samples, JSC's Astromaterials Curation Office hosts NASA's Astromaterials Curation digital repository and data access portal [http://curator.jsc.nasa.gov/], providing descriptions of the missions and collections, and critical information about each individual sample. Our office is designing and implementing several informatics initiatives to better serve the planetary research community. First, we are rehosting the basic database framework by consolidating legacy databases for individual collections and providing a uniform access point for information (descriptions, imagery, classification) on all of our samples. Second, we continue to upgrade and host digital compendia that summarize and highlight published findings on the samples (e.g., lunar samples, meteorites from Mars). We host high resolution imagery of samples as it becomes available, including newly scanned images of historical prints from the Apollo missions. Finally we are creating plans to collect and provide new data, including 3D imagery, point cloud data, micro CT data, and external links to other data sets on selected samples. Together, these individual efforts will provide unprecedented digital access to NASA's Astromaterials, enabling preservation of the samples through more specific and targeted requests, and supporting new planetary science research and collaborations on the samples

Banner News

https://openspace.dmacc.edu/banner_news/1433/thumbnail.jp

An Oct-1 binding site mediates activation of the gata2 promoter by BMP signaling

The gata2 gene encodes a transcription factor implicated in regulating early patterning of ectoderm and mesoderm, and later in numerous cell-specific gene expression programs. Activation of the gata2 gene during embryogenesis is dependent on the bone morphogenetic protein (BMP) signaling pathway, but the mechanism for how signaling controls gene activity has not been defined. We developed an assay in Xenopus embryos to analyze regulatory sequences of the zebrafish gata2 promoter that are necessary to mediate the response to BMP signaling during embryogenesis. We show that activation is Smad dependent, since it is blocked by expression of the inhibitory Smad6. Deletion analysis identified an octamer binding site that is necessary for BMP-mediated induction, and that interacts with the POU homeodomain protein Oct-1. However, this element is not sufficient to transfer a BMP response to a heterologous promoter, requiring an additional more proximal cooperating element. Based on recent studies with other BMP-dependent promoters (Drosophila vestigial and Xenopus Xvent-2), our studies of the gata2 gene suggest that POU-domain proteins comprise a common component of the BMP signaling pathway, cooperating with Smad proteins and other transcriptional activators

Evaluation of an Initial Specimen Diversion Device (ISDD) on Rates of Blood Culture Contamination in the Emergency Department

Introduction: Blood cultures are the gold standard for identifying bloodstream infections. The Clinical and Laboratory Standards Institute recommends a blood culture contamination rate of &lt;3%. Contamination can lead to misdiagnosis, increased length of stay and hospital costs, unnecessary testing and antibiotic use. These reasons led to the development of initial specimen diversion devices (ISDD). The purpose of this study is to evaluate the impact of an initial specimen diversion device on rates of blood culture contamination in the emergency department.  Methods: This was a retrospective, multi-site study including patients who had blood cultures drawn in an emergency department. February 2018 to April 2018, when an ISDD was not utilized, was compared with June 2019 to August 2019, a period where an ISDD was being used. The primary outcome was total blood culture contamination. Secondary outcomes were total hospital cost, hospital and intensive care unit length of stay, vancomycin days of use, vancomycin serum concentrations obtained, and repeat blood cultures obtained.  Results: A statistically significant difference was found in blood culture contamination rates in the Pre-ISDD group vs the ISDD group (7.47% vs 2.59%, p&lt;0.001). None of the secondary endpoints showed a statistically significant difference. Conclusions: Implementation of an ISDD reduces blood culture contamination in a statistically significant manner. However, we were unable to capture any statistically significant differences in the secondary outcomes

Improving the Discoverability and Availability of Sample Data and Imagery in NASA's Astromaterials Curation Digital Repository Using a New Common Architecture for Sample Databases

The Astromaterials Acquisition and Curation Office at NASA's Johnson Space Center (JSC) is the designated facility for curating all of NASA's extraterrestrial samples. The suite of collections includes the lunar samples from the Apollo missions, cosmic dust particles falling into the Earth's atmosphere, meteorites collected in Antarctica, comet and interstellar dust particles from the Stardust mission, asteroid particles from the Japanese Hayabusa mission, and solar wind atoms collected during the Genesis mission. To support planetary science research on these samples, NASA's Astromaterials Curation Office hosts the Astromaterials Curation Digital Repository, which provides descriptions of the missions and collections, and critical information about each individual sample. Our office is implementing several informatics initiatives with the goal of better serving the planetary research community. One of these initiatives aims to increase the availability and discoverability of sample data and images through the use of a newly designed common architecture for Astromaterials Curation databases

Landscape-Scale Geospatial Assessment of Open Pine and Natural Grassland Condition for Northern Bobwhite in the Gulf Coastal Plains and Ozarks

The National Bobwhite Conservation Initiative 2.0 (NBCI) suggests \u3e13 million acres of pine forests and \u3e600,000 acres of grasslands have high potential for northern bobwhite (Colinus virginianus) conservation in the Southeast. The Gulf Coastal Plains and Ozarks Landscape Conservation Cooperative (LCC) identifies northern bobwhite as one of 15 indicator species for open pine/woodland/savanna and grassland/prairie ecological systems, and describes specific habitat conditions considered desirable as measurable landscape endpoints in each system as part of an Integrated Science Agenda (ISA). The ISA suggests bobwhite are limited by the habitat characteristics associated with basal area and canopy cover in pine systems, and patch size, vegetation density, bare ground, shrub cover, and warm-season grass density in grassland systems across the 180 million acre LCC. We conducted Rapid Ecological Assessments (REAs) of pine and grassland systems to describe where, how much, and in what condition the desired habitat conditions exist for each system. Using endpoint threshold values, the best available geospatial data, and a dichotomous decision tree approach, the pine and grassland REAs assigned per-pixel Condition Index Values (CIV) for the entire LCC. Results indicate 46% of the 48 million acres of pine or mixed-pine hardwood forests are in patches \u3e600 acres with one other endpoint present, but only 0.2% (100,000 acres) reflect all desired open pine conditions. In the grassland system, 48% of the 32 million acres of grassland were characterized by the presence of at least one desired condition, with no areas meeting all desired conditions. In many cases, areas with high CIV scores overlap areas classified as high and medium land use opportunities in NBCI 2.0, suggesting continuity of these independent empirical and expert-driven assessments. Understanding the current condition of pine and grassland systems in concert with NBCI potential acreage targets can help refine management and population objectives in NBCI and LCC conservation planning