6 research outputs found
Reflecting back and forwards: The ebb and flow of peer-reviewed reflective practice research in sport
Researchers in sport have claimed that reflective practice is important for competent practice. Evidence supporting this claim is sparse, highly theoretical and located within a variety of domains. The aim of this study was to assimilate and analyse the last 12 years of reflective practice literature within the sport domain in order to identify new areas of inquiry, emerging trends with regard to findings or methodology, and to identify implications for future research and practice. A sample of 68 papers published between 2001 and 2012 was examined, and investigated for the research locations, data collection methods utilised, and the professions and communities involved. The paper concludes with some suggestions for future research
High frequency oscillations during magnetar flares
The recent discovery of high frequency oscillations during giant flares from
the Soft Gamma Repeaters SGR 1806-20 and SGR 1900+14 may be the first direct
detection of vibrations in a neutron star crust. If this interpretation is
correct it offers a novel means of testing the neutron star equation of state,
crustal breaking strain, and magnetic field configuration. We review the
observational data on the magnetar oscillations, including new timing analysis
of the SGR 1806-20 giant flare using data from the Ramaty High Energy Solar
Spectroscopic Imager (RHESSI) and the Rossi X-ray Timing Explorer (RXTE). We
discuss the implications for the study of neutron star structure and crust
thickness, and outline areas for future investigation.Comment: 5 pages, 1 figure, to appear in the proceedings of the conference
"Isolated Neutron Stars: from the Interior to the Surface" (April 2006,
London), eds. D. Page, R. Turolla, & S. Zane, Astrophysics & Space Science in
pres
Multiplatform Analysis of 12 Cancer Types Reveals Molecular Classification within and across Tissues of Origin
Recent genomic analyses of pathologically-defined tumor types identify âwithin-a-tissueâ disease subtypes. However, the extent to which genomic signatures are shared across tissues is still unclear. We performed an integrative analysis using five genome-wide platforms and one proteomic platform on 3,527 specimens from 12 cancer types, revealing a unified classification into 11 major subtypes. Five subtypes were nearly identical to their tissue-of-origin counterparts, but several distinct cancer types were found to converge into common subtypes. Lung squamous, head & neck, and a subset of bladder cancers coalesced into one subtype typified by TP53 alterations, TP63 amplifications, and high expression of immune and proliferation pathway genes. Of note, bladder cancers split into three pan-cancer subtypes. The multi-platform classification, while correlated with tissue-of-origin, provides independent information for predicting clinical outcomes. All datasets are available for data-mining from a unified resource to support further biological discoveries and insights into novel therapeutic strategies