Gelatin/carboxymethyl cellulose mucoadhesive films with lysozyme: Development and characterization

The goal of our study is to develop and characterize mucoadhesive films with entrapped lysozyme based on gelatin/sodium carboxymethyl cellulose as perspective antimicrobial preparation. Lysozyme in mucoadhesive films retains more than 95 % of its initial activity for 3 years of storage. Different physical-chemical and biochemical characteristics of entrapped enzyme were evaluated, such as film thickness, weight, time of dissolution in water, bioadhesive force, in vitro lysozyme release, pH- and thermoprofiles of hydrolytic activity, effect of γ-sterilization, etc. We have shown that gelatin/sodium carboxymethyl cellulose films have adhesive force on the level of 4380 Pa. Scanning electron microscopy images shows the relative uniformity of the gelatin surface with entrapped lysozyme. Mucoadhesive films with lysozyme have 100% bactericidal effect on the test strain, Staphylococcus aureus ATCC 25923 F - 49 and thus could be considered as a perspective antimicrobial preparation

Higher borides and oxygen-enriched Mg-B-O inclusions as possible pinning centers in nanostructural magnesium diboride and the influence of additives on their formation

The study of high pressure (2 GPa) synthesized MgB2-based materials allows us to conclude that higher borides (with near MgB12 stoichiometry) and oxygen-enriched Mg-B-O inclusions can be pinning centers in nanostructural magnesium diboride matrix (with average grain sizes of 15-37 nm). It has been established that additions of Ti or SiC as well as manufacturing temperature can affect the size, amount and distribution of these inclusions in the material structure and thus, influence critical current density. The superconducting behavior of materials with near MgB12 stoichiometry of matrix is discussed.Comment: 4 pages, 1 figues, presented at VORTEX VI-2009, accepted for Physica

Technological effectiveness of modern education: features, traditions, innovations

The purpose of the study is to analyze the experience in organizing the learning process at a university using digital technologies, aimed at realizing the content of pedagogical education in the context of its structural components and indicators of students’ readiness to work in an educational institution. The positive and negative aspects of the use of IT- technologies in the formation of the experience of professional and pedagogical activities of students in the direction of “Pedagogical education” are noted. The relevance of using digital technologies in the educational process is dictated by the prevailing socio-cultural conditions, the development of information and communication means of transmission and information. At the same time, the problem is the unwillingness of the faculty, students, to their use for several reasons: news, illiteracy, lack of equipment in detail-spatial environment of technical means, the quality of Internet connection. And technologies which provide ability to save dialogicality pedagogical culture, allowing to establish a dialogue in the systems “teacher-student”, “student-teacher” and the polylogue “student-teacher-students” are particularly in demand. The use of the technology “Immersion in professional and pedagogical activity through culture with the support of the teacher” allows the teacher to conduct a dialogue with students and purposefully form their readiness for pedagogical activity in modern conditions based on the acceptance of the values of pedagogical culture and identification in her, personal and semantic attitude to labor functions for the provision of educational services for the main educational programs of educational organizations of different levels

The Mathematical Description for the Electropolymerization of Electrochemically Modified Monomers in Galvanostatic Mode

Математически описана система с электрополимеризацией электрохимически модифицированных органических мономеров в гальваностатическом режиме. Соответствующая математическая модель была проанализирована с помощью линейной теории устойчивости и бифуркационного анализа. Показано, что причиной автоколебательного поведения в таких системах могут быть влияния на ДЭС электрохимических реакций на первой и второй стадиях. Условия устойчивости стационарного состояния, а также монотонной неустойчивости также были найденыThe system with galvanostatic electropolymerization of electrosynthetized monomers was described mathematically. The correspondent mathematical model was analyzed by using of linear stability theory and bifurcation analysis. It was shown that the oscillatory behavior may be caused by the influences on DEL of electrochemical reactions on the first and the second stage. The steady-state stability conditions and the conditions for the monotonic instability were also foun

The Mathematical Description for the Electropolymerization of Electrochemically Modified Monomers in Galvanostatic Mode

Математически описана система с электрополимеризацией электрохимически модифицированных органических мономеров в гальваностатическом режиме. Соответствующая математическая модель была проанализирована с помощью линейной теории устойчивости и бифуркационного анализа. Показано, что причиной автоколебательного поведения в таких системах могут быть влияния на ДЭС электрохимических реакций на первой и второй стадиях. Условия устойчивости стационарного состояния, а также монотонной неустойчивости также были найденыThe system with galvanostatic electropolymerization of electrosynthetized monomers was described mathematically. The correspondent mathematical model was analyzed by using of linear stability theory and bifurcation analysis. It was shown that the oscillatory behavior may be caused by the influences on DEL of electrochemical reactions on the first and the second stage. The steady-state stability conditions and the conditions for the monotonic instability were also foun

The effect of high-pressure synthesis on flux pinning in MgB2-based superconductors

International audienceIncreasing the pressure during manufacturing MgB2 enhances the volume pinning force and moves the position of the maximum to higher magnetic fields. A similar shift was observed when Ti or SiC was added and the maximum of the volume pinning force was found at higher fields in in situ synthesized materials than in ex situ sintered samples. We attribute the observed changes to Mg–B–O oxygen-enriched regions and grains of higher magnesium borides in the MgB2 matrix. High-temperature processed materials demonstrated mainly point or mixed pinning while grain boundary pinning dominated after low-temperature synthesis

The effect of high-pressure synthesis on flux pinning in MgB2-based superconductors

International audienceIncreasing the pressure during manufacturing MgB2 enhances the volume pinning force and moves the position of the maximum to higher magnetic fields. A similar shift was observed when Ti or SiC was added and the maximum of the volume pinning force was found at higher fields in in situ synthesized materials than in ex situ sintered samples. We attribute the observed changes to Mg–B–O oxygen-enriched regions and grains of higher magnesium borides in the MgB2 matrix. High-temperature processed materials demonstrated mainly point or mixed pinning while grain boundary pinning dominated after low-temperature synthesis

High Pressure Synthesized Magnesium Diboride- and Dodecaboride-Based Superconductors: Structure and Properties

International audienc