Design and Performance of the Data Acquisition System for the NA61/SHINE Experiment at CERN

This paper describes the hardware, firmware and software systems used in data acquisition for the NA61/SHINE experiment at the CERN SPS accelerator. Special emphasis is given to the design parameters of the readout electronics for the 40m^3 volume Time Projection Chamber detectors, as these give the largest contribution to event data among all the subdetectors: events consisting of 8bit ADC values from 256 timeslices of 200k electronic channels are to be read out with ~100Hz rate. The data acquisition system is organized in "push-data mode", i.e. local systems transmit data asynchronously. Techniques of solving subevent synchronization are also discussed.Comment: 14 pages, 13 figure

Safety and risks of CBD oils purchased online: unveiling uncertain quality and vague health claims

Introduction: The unmet need for highly effective, naturally derived products with minimal side effects results in the over-popularity of ever-newer medicinal plants. In the middle of 2010, products containing cannabidiol (CBD), one of the special metabolites of Cannabis sativa , started to gain popularity. For consumers and healthcare providers alike, the legal context surrounding the marketing of CBD products is not entirely clear, and the safety of using some products is in doubt. Companies in the online medicinal product market profit from the confusion around CBD oils

In vivo screening of diterpene alkaloids using bdelloid rotifer assays

The group of diterpene alkaloids contains numerous compounds with complex chemistry and diverse pharmacological activities. Beside toxicity, these compounds possess activity on the cardiovascular system, tumor cell lines and nervous system. The pharmacological properties have been described using in vitro and in vivo techniques; however, the bioactivities of many compounds have not thoroughly been studied. Here we report on the in vivo evaluation of ten diterpene alkaloids using bdelloid rotifer assays. Napelline exerted toxic effects on rotifers, while wide tolerance range was observed for other investigated compounds. Weak toxicity of songorine is supported by our experiment. Toxicological data for senbusine A, senbusine C, septentrioidine and hetisinone are reported for the first time