A Pythagoras Tree Shape Fractal Antenna for Multiband Applications

Given a large graph G = (V, E) with millions of nodes and edges, how do we compute its connected components efficiently? Recent work addresses this problem in map-reduce, where a fundamental trade-off exists between the number of map- reduce rounds and the communication of each round. Denoting d the  diameter  of  the  graph,  and  n  the  number  of  nodes in the largest component, all prior techniques for map-reduce either require a linear, Θ(d), number of rounds, or a quadratic, Θ(n|V | + |E|), communication per round. We propose here two efficient map-reduce algorithms: (i) Hash-Greater-to-Min, which is a randomized algorithm based on PRAM techniques, requiring O(log n) rounds and O(|V | + |E|) communication per round, and (ii) Hash-to-Min, which is a novel algorithm, provably finishing in O(log n) iterations for path graphs. The proof technique used for Hash-to-Min is novel, but not tight, and it is actually faster than Hash-Greater-to- Min in practice. We conjecture that it requires 2 log d rounds and 3(|V | + |E|) communication per  round, as  demonstrated in our experiments. Using secondary sorting, a standard map- reduce feature, we scale Hash-to-Min to graphs with very large connected components. Our techniques for connected components can be applied to clustering as well. We propose a novel algorithm for agglomera- tive single linkage clustering in map-reduce. This is the first map- reduce algorithm for clustering in at most O(log n) rounds, where n is the size of the largest cluster. We show the effectiveness of all our algorithms through detailed experiments on large synthetic as well as real-world dataset

Multi-component olivine for lithium-ion hybrid capacitor

A lithium-ion hybrid capacitor comprising of a battery type multi-component olivine (LiMn1/3Co1/3Ni1/3PO4) cathode and a capacitive type carbon negative electrode is reported. Olivine phosphate synthesized with chelating agent's polyvinylpyrrolidone (PVP) or triethanolamine (TEA) showed uniform carbon coating through in-situ process exhibiting a surface area 5.1 m2/g with porosity 0.02 cm2/g. The surface area for commercial carbon electrode was observed to be 1450 m2/g with high porosity 0.76 cm2/g. Galvanostatic charge/discharge cycling tests were conducted in the coin cells, olivine vs. Li, offering a cell voltage of 4.75 V vs. Li with a maximum specific capacitance of 125 F/g. In the case of olivine vs. carbon in a lithium-ion hybrid device delivered a high discharge capacitance of 86 F/g at a specific current of 0.12 A/g with a cycling retention of 53 F/g (38% loss) after 250 cycles. The obtained performance of PVP synthesized olivine material is manifested to uniform carbon coating and the trapped organic products that provide pathways for facile electrochemical reactions than their TEA counterparts

Cone bean computed tomographic evaluation, localization and surgical management of Non-syndromic Inverted mesiodens in close proximity to nasal floor: Case report and review of literature

Supernumerary teeth are numerical developmental anomaly defined as an additional teeth present as a complement to the normal dentition. Mesiodens is relatively a most common anomaly in the developing dentition stages. This article presents the case report of a 6-year old girl child who with the chief complaint of malaligned upper front teeth. On detailed clinical and radiographic examination the presence of vertically impacted mesiodens in the anterior region with close proximity to nasal floor was noted. The child didn’t have any relevant medical or dental history. Due to pertaining complexity and its close proximation to the nasal floor it was decided to carryout extraction of mesiodens under general anesthesia. Following the extraction of mesiodens under general anesthesia after the scheduled recovery appropriate post-operative instructions were given to the child and their parents and the child was discharged. Follow up was scheduled after 1 week which showed uneventful healing of the surgical site and subsequent eruption of maxillary right lateral incisor. Mesiodens belong to the category of supernumerary teeth which can result numerous dentofacial defects if not removed promptly. Hence parents must have considerable attention and seek dental help whenever they notice an asymmetric pattern of teeth eruption in their children. In this case scenario the mesiodens were removed as it prevented the eruption of successor permanent teeth which henceforth resulted with considerable esthetic concerns for the child due to its prolonged retention within the dental arch

Forwarding Web Service Requests To A Single Service Instance in Service Oriented Networking

Abstract: Service providers within an enterprise network are often governed by client service contracts (CSC) that specify, among other constraints, the rate at which a particular service instance may be accessed. The service can be accessed via multiple points in a proxy tier configuration. The CSC and thus the rate specified have to be collectively respected by all the middleware appliances. The appliances locally shape the service requests to respect the global contract. Investigation is done in the case where the CSC limits the rate to a service to X requests with an enforcement/observation interval of T seconds. This paper extends, and investigates the Credit-based Algorithm in a production level enterprise network setting. CBA is a decentralized algorithm for service traffic shaping in middleware appliances

Modeling 3D Magma Dynamics Using a Discontinuous Galerkin Method

Discontinuous Galerkin (DG) and matrix-free finite element methods with a novel projective pressure estimation are combined to enable the numerical model- ing of magma dynamics in 2D and 3D using the library deal.II . The physical model is an advection-reaction type system consisting of two hyperbolic equations to evolve porosity and soluble mineral abundance and one elliptic equation to recover global pressure. A combination of a discontinuous Galerkin method for the advection equa- tions and a finite element method for the elliptic equation provide a robust and efficient solution to the channel regime problems of the physical system in 3D. A projective and adaptively applied pressure estimation is employed to significantly reduce the compu- tational wall time without impacting the overall physical reliability in the modeling of important features of melt and segregation, such as melt channel bifurcation in 2D and 3D time dependent simulations

Multilevel and Local Timestepping Discontinuous Galerkin Methods for Magma Dynamics

Discontinuous Galerkin (DG) method is presented for numerical modeling of melt migration in a chemically reactive and viscously deforming upwelling mantle column. DG methods for both advection and elliptic equations provide a robust and efficient solution to the problems of melt migration in the asthenospheric upper mantle. Assembling and solving the elliptic equation is the major bottleneck in these computations. To address this issue, adaptive mesh refinement and local timestepping methods have been proposed to significantly improve the computational wall time. The robustness of DG methods is demonstrated through two benchmark problems by modeling detailed structure of high-porosity dissolution channels and compaction-dissolution waves

Efficacy and safety of onasemnogene abeparvovec in children with spinal muscular atrophy type 1: real-world evidence from 6 infusion centres in the United Kingdom

Background: Real-world data on the efficacy and safety of onasemnogene abeparvovec (OA) in spinal muscular atrophy (SMA) are needed, especially to overcome uncertainties around its use in older and heavier children. This study evaluated the efficacy and safety of OA in patients with SMA type 1 in the UK, including patients ≥2 years old and weighing ≥13.5 kg. / Methods: This observational cohort study used data from patients with genetically confirmed SMA type 1 treated with OA between May 2021 and January 2023, at 6 infusion centres in the United Kingdom. Functional outcomes were assessed using age-appropriate functional scales. Safety analyses included review of liver function, platelet count, cardiac assessments, and steroid requirements. / Findings: Ninety-nine patients (45 SMA therapy-naïve) were treated with OA (median age at infusion: 10 [range, 0.6–89] months; median weight: 7.86 [range, 3.2–20.2] kg; duration of follow-up: 3–22 months). After OA infusion, mean ± SD change in CHOP-INTEND score was 11.0 ± 10.3 with increased score in 66/78 patients (84.6%); patients aged 100 U/L (95% CI, 2.3–223.7; P = 0.008) and 21.2-fold increased odds of steroid doubling, as per treatment protocol (95% CI, 2.2–209.2; P = 0.009) in patients weighing ≥13.5 kg versus <8.5 kg. Weight at infusion was positively correlated with steroid treatment duration (r = 0.43; P < 0.001). Worsening transaminitis, despite doubling of oral prednisolone, led to treatment with intravenous methylprednisolone in 5 children. Steroid-sparing immunosuppressants were used in 5 children to enable steroid weaning. Two deaths apparently unrelated to OA were reported. / Interpretation: OA led to functional improvements and was well tolerated with no persistent clinical complications, including in older and heavier patients. / Funding: Novartis Innovative Therapies AG provided a grant for independent medical writing services

Ancient mtDNA from the extinct Indian cheetah supports unexpectedly deep divergence from African cheetahs

Abstract: The Indian cheetah was hunted to extinction by the mid-20th century. While analysis of 139 bp of mitochondrial DNA (mtDNA) has confirmed that the Indian cheetah was part of the Asiatic subspecies (Acinonyx jubatus venaticus), the detailed relationships between cheetah populations remains unclear due to limited genetic data. We clarify these relationships by studying larger fragments of cheetah mtDNA, both from an Indian cheetah museum specimen and two African cheetah, one modern and one historic, imported into India at different times. Our results suggest that the most recent common ancestor of cheetah mtDNA is approximately twice as ancient as currently recognised. The Indian and Southeast African (Acinonyx jubatus jubatus) cheetah mtDNA diverged approximately 72 kya, while the Southeast and Northeast African (Acinonyx jubatus soemmeringii) cheetah mtDNA diverged around 139 kya. Additionally, the historic African cheetah sampled from India proved to have an A. j. jubatus haplotype, suggesting a hitherto unrecognised South African route of cheetah importation into India in the 19th century. Together, our results provide a deeper understanding of the relationships between cheetah subspecies, and have important implications for the conservation of A. j. venaticus and potential reintroduction of cheetahs into India

Ancient mtDNA from the extinct Indian cheetah supports unexpectedly deep divergence from African cheetahs

Abstract: The Indian cheetah was hunted to extinction by the mid-20th century. While analysis of 139 bp of mitochondrial DNA (mtDNA) has confirmed that the Indian cheetah was part of the Asiatic subspecies (Acinonyx jubatus venaticus), the detailed relationships between cheetah populations remains unclear due to limited genetic data. We clarify these relationships by studying larger fragments of cheetah mtDNA, both from an Indian cheetah museum specimen and two African cheetah, one modern and one historic, imported into India at different times. Our results suggest that the most recent common ancestor of cheetah mtDNA is approximately twice as ancient as currently recognised. The Indian and Southeast African (Acinonyx jubatus jubatus) cheetah mtDNA diverged approximately 72 kya, while the Southeast and Northeast African (Acinonyx jubatus soemmeringii) cheetah mtDNA diverged around 139 kya. Additionally, the historic African cheetah sampled from India proved to have an A. j. jubatus haplotype, suggesting a hitherto unrecognised South African route of cheetah importation into India in the 19th century. Together, our results provide a deeper understanding of the relationships between cheetah subspecies, and have important implications for the conservation of A. j. venaticus and potential reintroduction of cheetahs into India