Evaluating the optimal number of burr-holes for treating chronic subdural haematomas: good results from a single burr-hole?

Introduction. Chronic subdural haematomas (cSDH) are one of the most common types of traumatic intracranial lesion. Burr-hole craniostomy followed by closed-system drainage has become the treatment of choice. However, there is no definitive indication as to the number of burr-holes needed. Our aim was to to assess clinical and radiological outcomes taking into account the number of burr-holes made.Material and methods. A retrospective single-centre-study was performed including patients treated for cSDH by performing burr-hole craniostomy from 2012 to 2018. After collecting data regarding demographics, comorbidities, and clinical and radiological records, haematomas were grouped depending on the number of burr-holes made (Group 1: single burr-hole; Group 2: double burr-holes). Clinical and radiological outcomes were statistically compared between groups, as well as the main complications.Results. After collecting 171 patients, 205 cSDHs were analysed. 173 were treated with a single burr-hole (we called these Group 1) and 32 with double burr-holes (Group 2). No differences in preoperative characteristics were found between the groups, except for diabetes mellitus and previous antiplatelet/anticoagulation treatment. No radiological differences were found regarding haematoma volume (p = 0.7) or thickness (p = 0.3). Surgical site infection (p = 0.13), recurrence (p = 0.6), acute rebleeding (p = 0.25) and mortality (p = 0.94) were assessed without evidencing statistically significant differences. At the time of hospital discharge, most patients showed a remarkable clinical improvement, regardless of the number of burr-holes made (p = 0.7).Conclusions. This study suggests that cSDH can be efficiently evacuated by a single burr-hole craniostomy, a less invasive and shorter surgical procedure with quite good clinical outcomes and a low rate of complications

TODDLER Project (2010-2013) Towards Opportunities for Disadvantaged and Diverse Learners on the Early-childhood Road. European Union, Lifelong Learning Programme, Comenius.

TODDLER Project, Lifelong Learning Programme created opportunities for knowledge transfer and exchange through focusing on the development of provisions for toddlers and investigations of different approaches promoting learning in a child-centred way. Module materials explored strategies and good practice of provision of high-quality education and care for disadvantaged toddlers. A framework created a report on ‘Toddler in Europe the Context’ on ECEC systems and approaches used to support diverse and disadvantaged toddlers. Then explored topic areas of ‘Language Support in Multicultural Settings’, Supporting Wellbeing’ and ‘Enhancing Parental Involvement’ with ‘Educating the Reflective Practitioner’ underpinning all of this. The module materials were successfully trialled and completed being made available on the TODDLER website as a Course Reader, Course Lecture Materials, and resources. KU led the Report and Case Studies: Promoting the Wellbeing of Toddler’s within the European Union creating an innovative pedagogical approach ‘Reflective Story Boards’ using a description of the context of the strategy followed by photos with explanations and supported with further description /explanation making visible to all stakeholders how educators promote wellbeing for toddlers. The final report highlighted the Reflective Story Boards contribution reaching the goal of showing the educational potential of high quality ECEC (Final Report, 2011)

THE MEASURABILITY OF CONTROLLING PERFORMANCE

Abstract: The urge to increase the performance of company processes is ongoing. Surveys indicate however, that many companies do not measure the controlling performance with a defined set of key performance indicators. This paper will analyze three categories of controlling key performance indicators based on their degree of measurability and their impact on the financial performance of a company. Potential measures to optimize the performance of the controlling department will be outlined and put in a logical order. The aligning of the controlling activity with the respective management expectation will be discussed as a key success factor of this improvement project

Analele Universitatii din Timisoara. Seria matematica-informatica.

Voortzetting van: Analele Universitatii din Timisoara. Stiinte matematice (1969

Critical analysis of the projects of reduction, separation and reuse / recycling of ordinary solid residues, in the neighborhood The Fairs of Locality 10 of Engativá, (Bogotá) in the government periods of 2012 to the Present

Siendo el propósito central del trabajo de investigación, comprender el porqué de la problemática de residuos sólidos ordinarios en el barrio Las Ferias de la Localidad de Engativá-Bogotá y en ese sentido generar recomendaciones al respecto, se realiza un análisis crítico de los planes de desarrollo de los gobiernos Distritales “Bogotá Humana” y “Bogotá Mejor para Todos” basados en los programas de gobierno “Basura Cero” y el de “Infraestructura para el Desarrollo del Hábitat” respectivamente, bajo un enfoque sistémico, a través de cuatro categorías, tales como: difusión de la información, educación, participación ciudadana y articulación entre actores, con base en los proyectos identificados sobre reducción, separación y reutilización/reciclaje de los residuos sólidos ordinarios y su ejecución física respecto a las metas proyectadas en cada uno de ellos, en relación al barrio Las Ferias y la confrontación de información realizada por medio de recorridos por el barrio, encuestas y entrevistas, que permitieron corroborar la realización de algunos proyectos, su impacto según la apreciación de las personas así como también se pudo identificar que existe una alta desinformación, desarticulación entre los diferentes actores entre otros elementos, con lo cual luego del análisis por categorías, se dieron las respectivas recomendaciones, teniendo en cuenta como insumo principal las propuestas planteadas en el taller participativo “Construyendo un Territorio Limpio” realizado con la comunidad.Being the central purpose of the research work, to understand the reason for the problem of ordinary solid waste in the neighborhood of Las Ferias of the Engativa locality from Bogotá and in this sense to generate recommendations in this regard, a critical analysis of the development plans is made of the District Governments "Bogotá Humana" and "Bogotá Mejor para Todos" based on the government programs "Basura Cero" and "Infraestructura para el Desarrollo del Hábitat" respectively, under a systemic approach, through four categories, such as: dissemination of information, education, citizen participation and articulation between actors, based on the projects identified on reduction, separation and reuse / recycling of ordinary solid waste and its physical execution with respect to the projected goals in each one of them, in relation to the Las Ferias neighborhood and the confrontation of information made through tours of the neighborhood, surveys and interviews, which allowed corroborating the realization of some projects, their impact according to the appreciation of the people as well as it could be identified that there is a high disinformation, disarticulation between the different actors among other elements, with which after the analysis by categories, the respective recommendations were given, taking into account as main input the proposed proposals in the participatory workshop "Cons Building a Clean Territory "made with the community

[Formal representation and reasoning for microscopic medical image-based prognosis] ( [application to breast cancer grading].)

Cette thèse aborde l'aide du pronostic basée sur l'image et les ontologies médicales, en utilisant la représentation des connaissances et le raisonnement pour les très grandes images microscopiques. Une application médicale particulière dans laquelle une assistance de type pronostic est nécessaire est la graduation du cancer du sein. Même si cela est considéré comme un outil d'évaluation essentiel dans la pratique de pathologie moderne les principaux problèmes posés par la procédure manuelle de pronostic sont: la nécessité des connaissances, attention et temps. D'autre part, le manque de reprédentation sémantique formelle standardisée pour aider l'indexation et la classification de la terminologie, ainsi que l'utilisation d'un mécanisme d'inférence pour assister le graduation représentent des problématiques clé du domaine. Dans ce sens, cette étude propose une représentation formelle qualitative pour la graduation du cancer du sein ainsi qu'une ontologie d'application Brest cancer Grading Ontology (BCGO) pour décrire les connaissances d'une manière cohérente. Une autre question que nous adressons en proposant l'ontologie, est le fossé sémantique entre les concepts sémantiques de haut niveau et les caractéristiques de l'image de bas niveau. En plus, nous proposonsun soutien de théorie spatiale pour la représentation des relations spatiales entre les concepts spécifiques à la graduation du cancer du sein. L'ontologie BCGO est intégré dans une plateforme microscopique cognitive virtuelle MICO, pour l'exploitation visuelle, l'indexation et l'extration sémantique des l'images microscopiques.This thesis addresses ontology-driven prognosis assistance using knowledge representation and reasoning for very large microscopic medical images. One particular medical application in which prognosis assistance is needed is the breast cancer grading. Althrough this is considered the key assessment tool in prognosis of modern pathology pratice, the main problems of the manual procedure are: time constraint, the need of knowledge and attention. More over, the lack of formal standardized semantic representation for the indexing and classification of terminology and the lack of an inference mechanism to assist the grading are key issues of the domain. To this end, we propose a qualitativ ontological representation of breast cancer grading, an application ontology entlited Breast Cancer Grading Ontology (BCGO) based on OWL-DL and SWRL formalisms. Using this approach, the thesis also tackles the semantic gap between the high-level semantic concepts and the low-level image features. Additionally, we propose a spatial theory support for the representation of the spatial relations between the spatial concepts of the breast cancer grading. This ontology is integrated into a cognitive microscope framework MICO, guiding the image exploration, semantic indexing and retrieval of the microscopic imagesBESANCON-BU Sciences Staps (250562103) / SudocSudocFranceF