Nucleon-nucleon scattering within a multiple subtractive renormalization approach

A methodology to renormalize the nucleon-nucleon interaction, using a recursive multiple subtraction approach to construct the kernel of the scattering equation, is presented. We solve the subtracted scattering equation with the next-leading-order (NLO) and next-to-next-leading-order (NNLO) interactions. The results are presented for all partial waves up to $j=2$, fitted to low-energy experimental data. In our renormalizaton group invariant method, when introducing the NLO and NNLO interactions, the subtraction energy emerges as a renormalization scale and the momentum associated with it comes to be about the QCD scale ($\Lambda_{QCD}$), irrespectively to the partial wave.Comment: Final versio

Power counting and renormalization group invariance in the subtracted kernel method for the two-nucleon system

We apply the subtracted kernel method (SKM), a renormalization approach based on recursive multiple subtractions performed in the kernel of the scattering equation, to the chiral nucleon-nucleon (NN) interactions up to next-to-next-to-leading-order (NNLO). We evaluate the phase-shifts in the 1S0 channel at each order in Weinberg's power counting scheme and in a modified power counting scheme which yields a systematic power-law improvement. We also explicitly demonstrate that the SKM procedure is renormalization group invariant under the change of the subtraction scale through a non-relativistic Callan-Symanzik flow equation for the evolution of the renormalized NN interactions.Comment: Accepted for publication in Journal of Physics G: Nuclear and Particle Physic

Doentes Oncológicos com Síndrome Coronária Aguda Não Têm Maior Risco Hemorrágico Quando Comparados com Doentes com Características Similares - Uma Análise de Emparelhamento de Score de Propensão do Registo ProACS

Introduction: The management of acute coronary syndrome (ACS) in malignancy is challenging due to higher bleeding risk. Methods: We analyzed patients with cancer (active or in the previous five years) prospectively included in the ProACS registry between 2010 and 2019. Our aim was to assess safety (major bleeding, primary endpoint) and secondary efficacy endpoints (in-hospital mortality and combined in-hospital mortality, reinfarction and ischemic stroke) of ACS treatment. Propensity score matching analysis (1:1) was further performed to better understand predictors of outcomes. Results: We found 934 (5%) cancer patients out of a total of 18 845 patients with ACS. Cancer patients had more events: major bleeding (2.9% vs. 1.5%), in-hospital mortality (5.8% vs. 3.4%) and the combined endpoint (7.4% vs. 4.9%). The primary endpoint was related to cancer diagnosis (OR 1.97), previous bleeding (OR 7.09), hemoglobin level (OR 4.94), atrial fibrillation (OR 3.50), oral anticoagulation (OR 3.67) and renal dysfunction. Mortality and the combined secondary endpoint were associated with lower use of invasive coronary angiography and antiplatelet and neurohormonal blocker therapy. After propensity score matching (350 patients), there were no statistically significant differences in endpoints between the populations. Conclusion: Bleeding risk was not significant higher in the cancer population compared to patients with similar characteristics, nor were mortality or ischemic risk. The presence of cancer should not preclude simultaneous ACS treatment.info:eu-repo/semantics/publishedVersio

Subtractive renormalization of one-pion-exchange and contact interactions

A recursive subtractive renormalization of the scattering equation is applied to the nucleon-nucleon ¹S0 channel with one-pion-exchange plus derivative contact interactions. This method can be easily extended to any derivative order of the singular interaction. Although we limit this work to the singlet partial wave, the method can be used as well in higher waves and coupled channels. The ¹S0 renormalization parameters are fitted to the data.880883Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Dapagliflozin Impact on the Exercise Capacity of Non-Diabetic Heart Failure with Reduced Ejection Fraction Patients

Background: Dapagliflozin has been shown to reduce morbidity and mortality in Heart Failure with reduced Ejection Fraction (HFrEF), but its impact on exercise capacity of non-diabetic HF outpatients is unknown. Methods: Adult non-diabetic HF patients with a left ventricular ejection fraction (LVEF) <50% were randomized 1:1 to receive dapagliflozin 10 mg or to continue with HF medication. Patients underwent an initial evaluation which was repeated after 6 months. The variation of several clinical parameters was compared, with the primary endpoint being the 6 month peak oxygen uptake (pVO2) variation. Results: A total of 40 patients were included (mean age 61 ± 13 years, 82.5% male, mean LVEF 34 ± 5%), half being randomized to dapagliflozin, with no significant baseline differences between groups. The reported drug compliance was 100%, with no major safety events. No statistically significant difference in HF events was found (p = 0.609). There was a 24% reduction in the number of patients in New York Heart Association (NYHA) class III in the treatment group as opposed to a 15.8% increase in the control group (p = 0.004). Patients under dapagliflozin had a greater improvement in pVO2 (3.1 vs. 0.1 mL/kg/min, p = 0.030) and a greater reduction in NT-proBNP levels (-217.6 vs. 650.3 pg/mL, p = 0.007). Conclusion: Dapagliflozin was associated with a significant improvement in cardiopulmonary fitness at 6 months follow-up in non-diabetic HFrEF patients.info:eu-repo/semantics/publishedVersio

Nitrogênio e fluxos de óxido nitroso em sistemas agrícolas integrados e Cerrado nativo.

O N2O, dentre os gases de efeito estufa, é o que possui maior importância para o setor agropecuário devido às suas emissões estarem relacionadas com a dinâmica de nitrogênio que está diretamente associada às exigências desse nutriente pelos sistemas integrados. O objetivo desse trabalho foi avaliar nitrogênio mineral e fluxos de N2O no solo em sistemas ILPF intercalado com renques de Eucalyptus urograndis, ILP e Cerrado Nativo. O experimento foi implantado em Latossolo Vermelho, com blocos ao acaso e 3 repetições. As amostras foram coletadas em câmaras estáticas e as concentrações de N2O determinadas em cromatógrafo gasoso. A amostragem de solo foi realizada na camada de 0-5 cm. Os resultados demonstram picos de emissão no sistema ILP, que corresponderam aos maiores teores de nitrato com 10 ppm em novembro de 2012 no ILP e em fevereiro de 2013 no ILP e ILPF. As concentrações de amônio no Cerrado Nativo atingiram picos de até 100 ppm, o que pode estar associado ao baixo pH, condição desfavorável à atividade de microrganismos nitrificantes. Portanto, a forma amoniacal predomina no Latossolo sob vegetação de Cerrado Nativo e a forma nítrica no solo sob ILP e ILPF, sendo que os maiores fluxos de N2O no solo foram determinados no sistema ILP

Recursive renormalization of the singlet one-pion-exchange plus point-like interactions

The subtracted kernel approach is shown to be a powerful method to be implemented recursively in scattering equations with regular plus point-like interactions. The advantages of the method allows one to recursively renormalize the potentials, with higher derivatives of the Dirac-delta, improving previous results. The applicability of the method is verified in the calculation of the $^1S_0$ nucleon-nucleon phase-shifts, when considering a potential with one-pion-exchange plus a contact interaction and its derivatives. The $^1S_0$ renormalization parameters are fitted to the data. The method can in principle be extended to any derivative order of the contact interaction, to higher partial waves and to coupled channels.Comment: 12 pages, 3 figure

O Valor Prognóstico do Ponto Ótimo Cardiorrespiratório após Prova de Esforço Cardiorrespiratória Submáxima na Insuficiência Cardíaca

Introduction: Peak oxygen consumption (pVO2) is a key parameter for assessing the prognosis of heart failure with reduced ejection fraction (HFrEF). However, it is less reliable when the cardiopulmonary exercise test (CPET) is not maximal. Objective: To compare the prognostic power of various exercise parameters in submaximal CPET. Methods: Adult patients with HFrEF undergoing CPET in a tertiary center were prospectively assessed. Submaximal CPET was defined as a respiratory exchange ratio ≤1.10. Patients were followed for one year for the primary endpoint of cardiac death and urgent heart transplantation (HT). Various CPET parameters were analyzed as potential predictors of the combined endpoint and their prognostic power (area under the curve [AUC]) was compared using the Hanley-McNeil test. Results: CPET was performed in 442 HFrEF patients (mean age 56±12 years, 80% male), of whom 290 (66%) had a submaximal CPET. Seventeen patients (6%) reached the primary endpoint. The cardiorespiratory optimal point (COP) had the highest AUC value (0.989, p<0.001), and significantly higher prognostic power than other tested parameters, with pVO2 presenting an AUC of 0.753 (p=0.001). COP ≥36 had significantly lower survival free of HT during follow-up (p<0.001) and presented a sensitivity of 100% and a specificity of 89% for the primary endpoint. Conclusion: COP had the highest prognostic power of all parameters analyzed in a submaximal CPET. This parameter can help stratify HFrEF patients who are physiologically unable to reach a maximal level of exercise.info:eu-repo/semantics/publishedVersio

Composição química de plantas de cobertura como indicador de emissão de N2O.

A versão atual do Guia para Elaboração de Inventários Nacionais de Emissões de Gases de Efeito Estufa do IPCC adicionou a quantificação da contribuição de emissões de N2O em decorrência da decomposição de resíduos vegetais no cálculo do fator de emissão de óxido nitroso. Assim, este trabalho teve como objetivo analisar parâmetros (lignina, celulose, hemiceluloses, N) relacionados ao processo de decomposição de plantas de cobertura indicadores do potencial de emissão de N2O em sistema plantio direto no Cerrado. As seguintes espécies vegetais foram analisadas quanto aos teores de lignina, FDA, FDN, N total e conteúdo de N: Canavalia brasiliensis; Cajanus cajan; Mucuna aterrima; Crotalaria juncea; Pennisetum glaucum; Sorgum bicholor; Brachiaria ruziziensis;Triticum aestivum, Raphanus sativus e vegetação espontânea. Os menores teores de lignina foram observados em tecido vegetal de Brachiaria ruziziensis, Pennisetum glaucum e Canavalia brasiliensis e os conteúdos de N mais elevados em Canavalia brasiliensis. Porém, o tecido vegetal de Pennisetum glaucum possui maior C:N. Assim, a qualidade dos resíduos vegetais de Brachiaria ruziziensis e Canavalia brasiliensis, que apresentam decomposição acelerada e elevada concentração de N, pode favorecer mineralização de nitrogênio, consequentemente, as emissões de N2O para atmosfera