A Unified Framework for Modality-Agnostic Deepfakes Detection

As AI-generated content (AIGC) thrives, deepfakes have expanded from single-modality falsification to cross-modal fake content creation, where either audio or visual components can be manipulated. While using two unimodal detectors can detect audio-visual deepfakes, cross-modal forgery clues could be overlooked. Existing multimodal deepfake detection methods typically establish correspondence between the audio and visual modalities for binary real/fake classification, and require the co-occurrence of both modalities. However, in real-world multi-modal applications, missing modality scenarios may occur where either modality is unavailable. In such cases, audio-visual detection methods are less practical than two independent unimodal methods. Consequently, the detector can not always obtain the number or type of manipulated modalities beforehand, necessitating a fake-modality-agnostic audio-visual detector. In this work, we introduce a comprehensive framework that is agnostic to fake modalities, which facilitates the identification of multimodal deepfakes and handles situations with missing modalities, regardless of the manipulations embedded in audio, video, or even cross-modal forms. To enhance the modeling of cross-modal forgery clues, we employ audio-visual speech recognition (AVSR) as a preliminary task. This efficiently extracts speech correlations across modalities, a feature challenging for deepfakes to replicate. Additionally, we propose a dual-label detection approach that follows the structure of AVSR to support the independent detection of each modality. Extensive experiments on three audio-visual datasets show that our scheme outperforms state-of-the-art detection methods with promising performance on modality-agnostic audio/video deepfakes.Comment: This work has been submitted to the IEEE for possible publication. Copyright may be transferred without notice, after which this version may no longer be accessibl

Clinical observation of sacubitril valsartan sodium in the treatment of resistant hypertension: A randomized clinical trial

ObjectiveTo investigate the effectiveness and safety of sacubitril valsartan sodium in the treatment of resistant hypertension (RH).MethodsThis study is a single-center, prospective, randomized controlled study. According to the inclusion and exclusion criteria, patients with RH who met the criteria were screened, and all patients adjusted their drug treatment (valsartan 80 mg, amlodipine 5 mg, and hydrochlorothiazide 12.5 mg). After 4 weeks of drug elution, the random envelope method was used for random grouping. The treatment group took sacubitril valsartan sodium 200 mg, amlodipine 5 mg, hydrochlorothiazide 12.5 mg, and the control group took valsartan 80 mg, amlodipine 5 mg, and hydrochlorothiazide 12.5 mg for 8 weeks. The 24 h ambulatory blood pressure (BP) and the echocardiography index using the office sphygmomanometer were observed in the patients.ResultsA total of 100 patients with RH were included in the two groups, with 50 cases in each group. There were no significant differences in sex, age, or comorbid diseases between the two groups. During the 8-week follow-up, the office BP of the research group were significantly decreased (24.78/17.86 mmHg) compared with those of the control group. In the research group the 24 h average BP, daytime average BP, and nighttime average BP were 144.84/79.82, 147.10/82.06, and 138.67/76.31 mmHg at baseline, and reduced to 128.96/73.32, 131.50/74.94, and 122.11/69.27 mmHg at week 8, which were significantly decreased (P < 0.05 or P < 0.01), and the left ventricular ejection fraction was significantly increased (P < 0.05), compared with the control group.ConclusionSacubitril valsartan sodium can effectively reduce BP and improve cardiac function in RH

A semi-analytical algorithm for deriving the particle size distribution slope of turbid inland water based on OLCI data: A case study in Lake Hongze

The particle size distribution (PSD) slope (ξ) can indicate the predominant particle size, material composition, and inherent optical properties (IOPs) of inland waters. However, few semi-analytical methods have been proposed for deriving ξ from the surface remote sensing reflectance due to the variable optical state of inland waters. A semi-analytical algorithm was developed for inland waters having a wide range of turbidity and ξ in this study. Application of the proposed model to Ocean and Land Color Instrument (OLCI) imagery of the water body resulted in several important observations: (1) the proposed algorithm (754 nm and 779 nm combination) was capable of retrieving ξ with R2 being 0.72 (p < 0.01, n = 60), and MAPE and RMSE being 4.37% and 0.22 (n = 30) respectively; (2) the ξ in HZL was lower in summer than other seasons during the period considered, this variation was driven by the phenological cycle of algae and the runoff caused by rainfall; (3) the band optimization proposed in this study is important for calculating the particle backscattering slope (η) and deriving ξ because it is feasible for both algae dominant and sediment governed turbid inland lakes. These observations help improve our understanding of the relationship between IOPs and ξ, which are affected by different bio-optic processes and algal phenology in the lake environment

Search for an axion-like particle in J/ψJ/\psi radiative decays

We search for an axion-like particle (ALP) $a$ through the process $\psi(3686)\rightarrow\pi^+\pi^-J/\psi$, $J/\psi\rightarrow\gamma a$, $a\rightarrow\gamma\gamma$ in a data sample with $(2708.1\pm14.5)\times10^6$ $\psi(3686)$ events collected by the BESIII detector. No significant ALP signal is observed over the expected background, and the upper limits on the branching fraction of the decay $J/\psi\rightarrow\gamma a$ and the ALP-photon coupling constant $g_{a\gamma\gamma}$ are set at the 95\% confidence level in the mass range of 0.165\leq m_a\leq2.84\,\mbox{GeV}/c^2. The limits on $\mathcal{B}(J/\psi\rightarrow\gamma a)$ range from $8.3\times10^{-8}$ to $1.8\times10^{-6}$ over the search region, and the constraints on the ALP-photon coupling are the most stringent to date for 0.165\leq m_a\leq1.468\,\mbox{GeV}/c^2.Comment: 10 pages, 5 figure

Production of doubly-charged Δ\Delta baryon in e+e−e^{+}e^{-} annihilation at energies from 2.3094 to 2.6464 GeV

The processes $e^{+}e^{-} \to \Delta^{++}\bar{\Delta}^{--}$ and $e^{+}e^{-}\to \Delta^{++} \bar{p} \pi^{-} + c.c.$ are studied for the first time with $179~{\rm pb}^{-1}$ of $e^{+}e^{-}$ annihilation data collected with the BESIII detector at center-of-mass energies from $2.3094$ GeV to $2.6464$ GeV. No significant signal for the $e^{+}e^{-}\to \Delta^{++}\bar{\Delta}^{--}$ process is observed and the upper limit of the Born cross section is estimated at each energy point. For the process $e^{+}e^{-} \to \Delta^{++} \bar{p} \pi^{-} + c.c.$, a significant signal is observed at center-of-mass energies near 2.6454 GeV and the corresponding Born cross section is reported.Comment: 10 pages, 4 figure

Measurements of the electric and magnetic form factors of the neutron for time-like momentum transfer

We present the first measurements of the electric and magnetic form factors of the neutron in the time-like (positive $q^2$) region as function of four-momentum transfer. We explored the differential cross sections of the reaction $e^+e^- \rightarrow \bar{n}n$ with data collected with the BESIII detector at the BEPCII accelerator, corresponding to an integrated luminosity of 354.6 pb$^{-1}$ in total at twelve center-of-mass energies between $\sqrt{s} = 2.0 - 2.95$ GeV. A relative uncertainty of 18% and 12% for the electric and magnetic form factors, respectively, is achieved at $\sqrt{s} = 2.3935$ GeV. Our results are comparable in accuracy to those from electron scattering in the comparable space-like (negative $q^2$) region of four-momentum transfer. The electromagnetic form factor ratio $R_{\rm em}\equiv |G_E|/|G_M|$ is within the uncertainties close to unity. We compare our result on $|G_E|$ and $|G_M|$ to recent model predictions, and the measurements in the space-like region to test the analyticity of electromagnetic form factors.Comment: main paper: 9 pages, 6 figures, 3 tables; supplement: 9 pages, 28 table

Measurements of the branching fractions of the inclusive decays D0(D+)→π+π+π−X

Using eþe− annihilation data corresponding to an integrated luminosity of 2.93 fb−1 taken at a center-of mass energy of 3.773 GeV with the BESIII detector, we report the first measurements of the branching fractions of the inclusive decays D0 → πþπþπ−X and Dþ → πþπþπ−X, where pions from K0 S decays have been excluded from the πþπþπ− system and X denotes any possible particle combination. The branching fractions of D0ðDþÞ → πþπþπ−X are determined to be BðD0 → πþπþπ−XÞ¼ð17.60 0.11 0.22Þ% and BðDþ → πþπþπ−XÞ¼ð15.25 0.09 0.18Þ%, where the first uncertainties are statistical and the second systematic

A New Look at the Scalar Meson f0(500)f_0(500) via D+→π+π−ℓ+νℓD^+\to \pi^+\pi^-\ell^+\nu_\ell Decays

Using $2.93~\mathrm{fb}^{-1}$ of $e^+e^-$ collision data collected with the BESIII detector at the center-of-mass energy of 3.773 GeV, we investigate the semileptonic decays $D^+\to \pi^+\pi^- \ell^+\nu_\ell$ ($\ell=e$ and $\mu$). The $D^+\to f_0(500)\mu^+\nu_\mu$ decay is observed for the first time. By analyzing simultaneously the differential decay rates of $D^+\to f_0(500) \mu^+\nu_\mu$ and $D^+\to f_0(500) e^+\nu_e$ in different $\ell^+\nu_\ell$ four-momentum transfer intervals, the product of the relevant hadronic form factor $f^{f_0}_{+}(0)$ and the magnitude of the $c\to d$ Cabibbo-Kobayashi-Maskawa matrix element $|V_{cd}|$ is determined to be $f_{+}^{f_0} (0)|V_{cd}|=0.0787\pm0.0060_{\rm stat}\pm0.0033_{\rm syst}$ for the first time. With the input of $|V_{cd}|$ from the global fit in the standard model, we determine $f_{+}^{f_0} (0)=0.350\pm0.027_{\rm stat}\pm0.015_{\rm syst}$. The absolute branching fractions of $D^+\to f_0(500)_{(\pi^+\pi^-)}\mu^+\nu_\mu$ and $D^+\to \rho^0_{(\pi^+\pi^-)} \mu^+\nu_\mu$ are determined as $(0.72\pm0.13_{\rm stat}\pm0.10_{\rm syst})\times10^{-3}$ and $(1.64\pm0.13_{\rm stat}\pm0.11_{\rm syst})\times 10^{-3}$. Combining these results with those of previous BESIII measurements on their semielectronic counterparts from the same data sample, we test lepton flavor universality by measuring the branching fraction ratios ${\mathcal B}_{D^+\to \rho^0 \mu^+\nu_\mu}/{\mathcal B}_{D^+\to \rho^0 e^+\nu_e}=0.88\pm0.10$ and ${\mathcal B}_{D^+\to f_0(500) \mu^+\nu_\mu}/{\mathcal B}_{D^+\to f_0(500) e^+\nu_e}=1.14\pm0.28$, which are compatible with the standard model expectation.Comment: Supplemental Materials added in this versio

First Observation of a Three-Resonance Structure in e+e−→e^+e^-\rightarrow{non-open} Charm Hadrons

We report the measurement of the cross sections for $e^+e^-$$\rightarrow${nOCH} (nOCH stands for non-open charm hadrons) with improved precision at center-of-mass energies from 3.645 to 3.871 GeV. We observe for the first time a three-resonance structure in the energy-dependent lineshape of the cross sections, which are $\mathcal R(3760)$, $\mathcal R(3780)$ and $\mathcal R(3810)$ with significances of $9.4\sigma$, $15.7\sigma$, and $9.8\sigma$, respectively. The $\mathcal R(3810)$ is observed for the first time. We found two solutions in analysis of the cross sections. For solution I [solution II], we measure the mass, the total width and the product of electronic width and nOCH decay branching fraction to be $(3805.8 \pm 1.1 \pm 2.7)$ [$(3805.8 \pm 1.1 \pm 2.7)$] MeV/$c^2$, $(11.6 \pm 2.6 \pm 1.9)$ [$(11.5 \pm 2.5 \pm 1.8)$] MeV, and $(10.8\pm 3.2\pm 2.3)$ [$(11.0\pm 2.9\pm 2.4)$] eV for the $\mathcal R(3810)$, respectively. In addition, we measure the branching fractions ${\mathcal B}({\mathcal R}(3760)$$\rightarrow${nOCH}$)=(24.5 \pm 13.4 \pm 27.4)\% [(6.8 \pm 5.4 \pm 7.6)\%]$ for the first time, and ${\mathcal B}(\mathcal R(3780)$$\rightarrow${nOCH}$)=(11.6 \pm 5.8 \pm 7.8)\% [(10.3 \pm 4.5 \pm 6.9)\%]$. Moreover, we determine the open-charm (OC) branching fraction ${\mathcal B}({\mathcal R}$$(3760)\rightarrow${OC}$)=(75.5 \pm 13.4 \pm 27.4)\% [(93.2 \pm 5.4 \pm 7.6)\%]$, which supports the interpretation of $\mathcal R(3760)$ as an OC pair molecular state, but contained a simple four-quark state component. The first uncertainties are from fits to the cross sections, and the second are systematic

Amplitude analysis and branching fraction measurement of the decay D+→KS0π+π0π0D^{+} \to K_S^0\pi^+\pi^0\pi^0

Using 2.93 $\rm{fb}^{-1}$ of $e^+e^-$ collision data collected with the BESIII detector at the center-of-mass energy 3.773\,GeV, we perform the first amplitude analysis of the decay $D^+\to K_S^0\pi^+\pi^0\pi^0$ and determine the relative magnitudes and phases of different intermediate processes. The absolute branching fraction of $D^+\to K_S^0\pi^+\pi^0\pi^0$ is measured to be $(2.888\pm0.058_{\rm stat.}\pm0.069_{\rm syst.})\%$. The dominant intermediate processes are $D^+\to K_S^0a_1(1260)^+(\to \rho^+\pi^0)$ and $D^+\to \bar{K}^{*0}\rho^+$, with branching fractions of $(8.66\pm1.04_{\rm stat.}\pm1.39_{\rm syst.})\!\times \!10^{-3}$ and $(9.70\pm0.81_{\rm stat.}\pm0.53_{\rm syst.})\!\times \!10^{-3}$, respectively