98 research outputs found

    Scales of Conflict in Bronze Age to Iron Age Britain: Enemies both Outside and Within

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    Naviance Beyond the Counseling Office

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    Learning session conducted at the annual Minnesota ACT Statewide Conference, Minneapolis, MN. 2010, February

    Exploring aspects of the cognitive behavioural model of physical hoarding in relation to digital hoarding behaviours

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    While the hoarding of physical objects has been extensively explored, there is little research relating to the hoarding of digital materials. The research that has been conducted suggests that digital hoarding (DH) behaviours appears to have some similarities with physical hoarding (PH) behaviours, and can be just at psychologically distressing. This study uses the framework of the cognitive behavioural model of physical hoarding to explore digital hoarding behaviours, including possible similarities regarding emotional attachment to digital possessions, and possible links with Obsessive Compulsive Disorder (OCD) and indecisiveness. Two hundred and eighty two participants completed an online survey which measured levels of digital and physical hoarding, compulsive acquisition, OCD, indecisiveness, and mood. Strong emotional attachments to particular types of digital possessions were evident: this was especially true for photographs and videos. Significant positive relationships were found between all the variables measured. However, a regression analysis revealed that only OCD and physical hoarding scores were significant predictors of digital hoarding. Digital hoarding thus appears to share some of the features of physical hoarding. Implications, limitations and future research possibilities are discussed

    Sex-related changes in physical performance, wellbeing and neuromuscular function of elite Touch players during a four-day international tournament.

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    Accepted author manuscript version reprinted, by permission, from International Journal of Sports Physiology and Performance, 2020, 15(8): 1138–1146, https://doi.org/10.1123/ijspp.2019-0594. © Human Kinetics, Inc.Purpose: To examine the within- and between-sex physical performance, wellbeing and neuromuscular function responses across a four-day international touch rugby (Touch) tournament. Methods: Twenty females and twenty-one males completed measures of wellbeing (fatigue, soreness, sleep, mood, stress) and neuromuscular function (countermovement jump (CMJ) height, peak power output (PPO) and peak force (PF)) during a 4-day tournament with internal, external and perceptual loads recorded for all matches. Results: Relative and absolute total, low- (females) and high-intensity distance was lower on day 3 (males and females) (ES = -0.37 to -0.71) compared to day 1. Mean heart rate was possibly to most likely reduced during the tournament (except day 2 males) (ES = -0.36 to -0.74), whilst RPE-TL was consistently higher in females (ES = 0.02 to 0.83). The change in mean fatigue, soreness and overall wellbeing were unclear to most likely lower (ES = -0.33 to -1.90) across the tournament for both sexes, with greater perceived fatigue and soreness in females on days 3-4 (ES = 0.39 to 0.78). Jump height and PPO were possibly to most likely lower across days 2-4 (ES = -0.30 to -0.84), with greater reductions in females (ES = 0.21 to 0.66). Wellbeing, CMJ height, and PF were associated with changes in external, internal and perceptual measures of load across the tournament (2 = -0.37 to 0.39). Conclusions: Elite Touch players experience reductions in wellbeing, neuromuscular function and running performance across a 4-day tournament, with notable differences in fatigue and running between males and females, suggesting sex-specific monitoring and intervention strategies are necessary

    Biocompatible α‐Methylenation of Metabolic Butyraldehyde in Living Bacteria

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    Small molecule organocatalysts are abundant in all living organisms. However, their use as organocatalysts in cells has been underexplored. Herein, we report that organocatalytic aldol chemistry can be interfaced with living Escherichia coli to enable the α‐methylenation of cellular aldehydes using biogenic amines such as L‐Pro or phosphate. The biocompatible reaction is mild and can be interfaced with butyraldehyde generated from D‐glucose via engineered metabolism to enable the production of 2‐methylenebutanal (2‐MB) and 2‐methylbutanal (2‐MBA) by anaerobic fermentation, and 2‐methylbutanol (2‐MBO) by whole‐cell catalysis. Overall, this study demonstrates the combination of non‐enzymatic organocatalytic and metabolic reactions in vivo for the sustainable synthesis of valuable non‐natural chemicals that cannot be accessed using enzymatic chemistry alone

    The relationship between individual and composite FMSℱ score with the anthropometric and physical characteristics of elite Touch (rugby) players

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    Purpose 1). To describe and compare the movement patterns, anthropometric and physical characteristics of male and female Touch players; and 2). to examine the relationships between Functional Movement Screening (FMSℱ) scores and the anthropometric and physical characteristics. Methods This was a cross-sectional study with 35 elite Touch players (18 males, age=24.7±4.9 y and 17 females, age=26.7±5.2 y). Anthropometric (stature, body mass) and physical characteristics (sprint times, glycolytic change-of-direction test, and countermovement jump (CMJ) flight time and peak power) were assessed alongside movement patterns using the FMSℱ battery. Data were analysed for between-sex differences (independent t-test, Mann Whitney U) and associations (Spearman’s correlation coefficient). Results Between-sex differences in body mass (t=6.082, p<0.001), stature (t=9.247, p<0.001), CMJ flight time (t=3.576, p=0.001), relative CMJ peak power (t=6.578, p<0.001), 10 m sprint time (t=15.861, p<0.001), glycolytic change of direction test time (t=-11.831, p<0.001) and Yo-Yo IR1 (t=6.842, p<0.001) were observed. There was minimal differences for deep squat (Z=-1.036, p=0.443), in-line lunge (Z=-1.284, p=0.303), shoulder mobility (Z=-0.173, p=0.883), trunk stability push-up (Z=-0.896, p=0.483) and rotary stability (Z=-1.537, p=0.273). The correlation between total and individual FMSTM scores with anthropometric and physical characteristics ranged from trivial-to-moderate (r=-0.502 to 0.488). Conclusion The lack of difference for the FMSℱ composite score and small-to-trivial differences in individual scores allows a comparison between mixed populations within Touch. Whilst many of the correlations were trivial-to-small, there were differences between sexes in the associations and evidence that improvements in functional deficiencies could translate into improved physical performance

    A forensic STR profiling system for the Eurasian badger: A framework for developing profiling systems for wildlife species. Forensic Sci

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    Abstract Developing short tandem repeat (STR) profiling systems for forensic identification is complicated in animal species. Obtaining a representative number of individuals from populations, limited access to family groups and a lack of developed STR markers can make adhering to human forensic guidelines difficult. Furthermore, a lack of animal specific guidelines may explain why many wildlife forensic STR profiling systems developed to date have not appropriately addressed areas such as marker validation or the publication and analysis of population data necessary for the application of these tools to forensic science. Here we present a methodology used to develop an STR profiling system for a legally protected wildlife species, the Eurasian badger Meles meles. Ten previously isolated STR loci were selected based on their level of polymorphism, adherence to Hardy-Weinberg expectations and their fragment size. Each locus was individually validated with respect to its reproducibility, inheritance, species specificity, DNA template concentration and thermocycling parameters. The effects of chemical, substrate and environmental exposure were also investigated. All ten STR loci provided reliable and reproducible results, and optimal amplification conditions were defined. Allele frequencies from 20 representative populations in England and Wales are presented and used to calculate the level of population substructure (u) and inbreeding ( f). Accounting for these estimates, the average probability of identity (PI ave ) was 2.18 Â 10 À7 . This case study can act as a framework for others attempting to develop wildlife forensic profiling systems.

    Airborne methane remote measurements reveal heavy-tail flux distribution in Four Corners region

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    Methane (CH_4) impacts climate as the second strongest anthropogenic greenhouse gas and air quality by influencing tropospheric ozone levels. Space-based observations have identified the Four Corners region in the Southwest United States as an area of large CH_4 enhancements. We conducted an airborne campaign in Four Corners during April 2015 with the next-generation Airborne Visible/Infrared Imaging Spectrometer (near-infrared) and Hyperspectral Thermal Emission Spectrometer (thermal infrared) imaging spectrometers to better understand the source of methane by measuring methane plumes at 1- to 3-m spatial resolution. Our analysis detected more than 250 individual methane plumes from fossil fuel harvesting, processing, and distributing infrastructures, spanning an emission range from the detection limit ∌2 kg/h to 5 kg/h through ∌5,000 kg/h. Observed sources include gas processing facilities, storage tanks, pipeline leaks, and well pads, as well as a coal mine venting shaft. Overall, plume enhancements and inferred fluxes follow a lognormal distribution, with the top 10% emitters contributing 49 to 66% to the inferred total point source flux of 0.23 Tg/y to 0.39 Tg/y. With the observed confirmation of a lognormal emission distribution, this airborne observing strategy and its ability to locate previously unknown point sources in real time provides an efficient and effective method to identify and mitigate major emissions contributors over a wide geographic area. With improved instrumentation, this capability scales to spaceborne applications [Thompson DR, et al. (2016) Geophys Res Lett 43(12):6571–6578]. Further illustration of this potential is demonstrated with two detected, confirmed, and repaired pipeline leaks during the campaign

    Reducing bias in open-label trials where blinded outcome assessment is not feasible: strategies from two randomised trials

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    Background Blinded outcome assessment is recommended in open-label trials to reduce bias, however it is not always feasible. It is therefore important to find other means of reducing bias in these scenarios. Methods We describe two randomised trials where blinded outcome assessment was not possible, and discuss the strategies used to reduce the possibility of bias. Results TRIGGER was an open-label cluster randomised trial whose primary outcome was further bleeding. Because of the cluster randomisation, all researchers in a hospital were aware of treatment allocation and so could not perform a blinded assessment. A blinded adjudication committee was also not feasible as it was impossible to compile relevant information to send to the committee in a blinded manner. Therefore, the definition of further bleeding was modified to exclude subjective aspects (such as whether symptoms like vomiting blood were severe enough to indicate the outcome had been met), leaving only objective aspects (the presence versus absence of active bleeding in the upper gastrointestinal tract confirmed by an internal examination). TAPPS was an open-label trial whose primary outcome was whether the patient was referred for a pleural drainage procedure. Allowing a blinded assessor to decide whether to refer the patient for a procedure was not feasible as many clinicians may be reluctant to enrol patients into the trial if they cannot be involved in their care during follow-up. Assessment by an adjudication committee was not possible, as the outcome either occurred or did not. Therefore, the decision pathway for procedure referral was modified. If a chest x-ray indicated that more than a third of the pleural space filled with fluid, the patient could be referred for a procedure; otherwise, the unblinded clinician was required to reach a consensus on referral with a blinded assessor. This process allowed the unblinded clinician to be involved in the patient’s care, while reducing the potential for bias. Conclusions When blinded outcome assessment is not possible, it may be useful to modify the outcome definition or method of assessment to reduce the risk of bias
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