The Options Matrix Tool (OMT): A Strategic Decision-making Tool to Evaluate Decision Alternatives

The options matrix tool (OMT) is a spreadsheet-based decision making tool designed to help managers apply a set of decision criteria to a variety of alternatives or strategic options. It is particularly useful for decisions that require substantial judgment and for which numbers may not be available. By working through a series of decision-process steps, managers can establish criteria for the assessment and comparison of different possible alternatives and then compare choices. The tool allows managers to list and weigh various decision criteria deemed important for a given business situation or problem alternative. The most desirable option is then identified in a final spreadsheet along with an evaluation of each option. While the OMT is self-explanatory and designed to be easy to use, this report offers a brief description and examples of how to use the tool. Making judgment-based decisions among a variety of viable options is made easier when a systematic process is utilized such as the one offered in this tool

Observations of ozone production in a dissipating tropical convective cell during TC4

From 13 July–9 August 2007, 25 ozonesondes were launched from Las Tablas, Panama as part of the Tropical Composition, Cloud, and Climate Coupling (TC4) mission. On 5 August, a strong convective cell formed in the Gulf of Panama. World Wide Lightning Location Network (WWLLN) data indicated 563 flashes (09:00–17:00 UTC) in the Gulf. NO2 data from the Ozone Monitoring Instrument (OMI) show enhancements, suggesting lightning production of NOx. At 15:05 UTC, an ozonesonde ascended into the southern edge of the now dissipating convective cell as it moved west across the Azuero Peninsula. The balloon oscillated from 2.5–5.1 km five times (15:12–17:00 UTC), providing a unique examination of ozone (O3) photochemistry on the edge of a convective cell. Ozone increased at a rate of 1.6–4.6 ppbv/hr between the first and last ascent, resulting cell wide in an increase of (2.1–2.5)×106 moles of O3. This estimate agrees to within a factor of two of our estimates of photochemical lightning O3 production from the WWLLN flashes, from the radar-inferred lightning flash data, and from the OMI NO2 data (1.2, 1.0, and 1.7×106 moles, respectively), though all estimates have large uncertainties. Examination of DC-8 in situ and lidar O3 data gathered around the Gulf that day suggests 70–97% of the O3 change occurred in 2.5–5.1 km layer. A photochemical box model initialized with nearby TC4 aircraft trace gas data suggests these O3 production rates are possible with our present understanding of photochemistry

Optimizing a Personal Wine Cellar

This report takes what we believe to be the first scientific approach to optimizing a personal wine cellar. We identify the key factors related to optimizing a personal cellar: performance metrics, such as drinking the best possible wine; constraints, such as budget and cellar capacity; and decisions, specifically what to buy and when to consume the purchased wines. We describe the Personal Wine Cellar Optimizer, which is a tool designed to identify the optimum cellar management plan. Using scenarios differing in cellar capacity, cellar life, and wine budget, we examine how the constraints affect the optimal cellar management plan. Using an example of a real cellar, we also illustrate how the recommendations can be used to improve the cellar management. This report is cosponsored by The Vance A. Christian Beverage Management Center, Cornell University School of Hotel Administration

Organ-distribution of the Metabolite 2-Aminothiazoline-4-Carboxylic Acid in a Rat Model following Cyanide Exposure

The reaction of cyanide (CN−) with cystine to produce 2-aminothiazoline-4-carboxylic acid (ATCA) is one of the independent detoxification pathways of cyanide in biological systems. In this report, in vivo production of ATCA and its distributions in plasma and organs were studied after a subcutaneous sublethal dose of 4 mg/kg body weight potassium cyanide (KCN) administration to rats. At this sublethal dose of KCN, ATCA concentration was not significantly increased in the plasma samples, however, it was found significantly increased in liver samples. These results suggested that ATCA might not be a good diagnostic biomarker in plasma for sublethal cyanide exposure; however, liver could serve as the right organ for the detection of ATCA in post-mortem examinations involving cyanide exposure in military, firefighting, industrial and forensic settings

Mid-infrared quantum optics in silicon

Applied quantum optics stands to revolutionise many aspects of information technology, provided performance can be maintained when scaled up. Silicon quantum photonics satisfies the scaling requirements of miniaturisation and manufacturability, but at 1.55 $\mu$m it suffers from unacceptable linear and nonlinear loss. Here we show that, by translating silicon quantum photonics to the mid-infrared, a new quantum optics platform is created which can simultaneously maximise manufacturability and miniaturisation, while minimising loss. We demonstrate the necessary platform components: photon-pair generation, single-photon detection, and high-visibility quantum interference, all at wavelengths beyond 2 $\mu$m. Across various regimes, we observe a maximum net coincidence rate of 448 $\pm$ 12 Hz, a coincidence-to-accidental ratio of 25.7 $\pm$ 1.1, and, a net two photon quantum interference visibility of 0.993 $\pm$ 0.017. Mid-infrared silicon quantum photonics will bring new quantum applications within reach.Comment: 8 pages, 4 figures; revised figures, updated discussion in section 3, typos corrected, added referenc

Temperature dependence of the Kerr nonlinearity and two-photon absorption in a silicon waveguide at 1.55{\mu}m

We measure the temperature dependence of the two-photon absorption and optical Kerr nonlinearity of a silicon waveguide over a range of temperatures from 5.5 to 300 K at a wavelength of 1.55 {\mu}m. The two-photon absorption coefficient is calculated from the power dependent transmission of a 4.9 ps pulse. We observed a nearly two-fold decrease in the two-photon absorption coefficient from 0.76 cm/GW at 300K to 0.42 cm/GW at 5.5 K. The Kerr nonlinearity is inferred from the self-phase modulation induced spectral broadening of the transmitted pulse. A smaller reduction in Kerr nonlinearity from 5.2E-18 m^2/W at 300 K to 3.9E-18 m^2/W at 5.5 K is found. The increased ratio of Kerr to absorptive nonlinearity at low temperatures indicates an improved operation of devices that make use of a nonlinear phase shift, such as optical switches or parametric photon-pair sources. We examine how the heralding efficiency of a photon-pair source will change at low temperature. In addition, the modelling and experimental techniques developed can readily be extended to other wavelengths or materials of interest.Comment: 9 pages, 5 figure

Phase-resolved HST/STIS spectroscopy of the exposed white dwarf in the high-field polar AR UMa

Phase-resolved HST/STIS ultraviolet spectroscopy of the high-field polar AR UMa confirms that the WD photospheric Ly alpha Zeeman features are formed in a magnetic field of ~200 MG. In addition to the Ly alpha pi and sigma+ components, we detect the forbidden hydrogen 1s0->2s0 transition, which becomes ``enabled'' in the presence of both strong magnetic and electric fields. Our attempt in fitting the overall optical+UV low state spectrum with single temperature magnetic WD models remains rather unsatisfactory, indicating either a shortcoming in the present models or a new physical process acting in AR UMa. As a result, our estimate of the WD temperature remains somewhat uncertain, Twd=20000+-5000K. We detect a broad emission bump centered at ~1445A and present throughout the entire binary orbit, and a second bump near ~1650A, which appears only near the inferior conjunction of the secondary star. These are suggestive of low harmonic cyclotron emission produced by low-level (M-dot~1e-13 Msun/yr) accretion onto both magnetic poles. However, there is no evidence in the power spectrum of light variations for accretion in gas blobs. The observed Ly alpha emission line shows a strong phase dependence with maximum flux and redshift near orbital phase phi~0.3, strongly indicating an origin on the trailing hemisphere of the secondary star. An additional Ly alpha absorption feature with similar phasing as the Ly alpha emission, but a \~700km/s blueshift could tentatively be ascribed to absorption of WD emission in a moderately fast wind. We derive a column density of neutral hydrogen of NH=(1.1+-1.0)1e18 cm**-2, the lowest of any known polar.Comment: 26 pages, 10 figures, AAS TeX 5.0, accepted for publication in the Astrophysical Journa

Broccoli (Brassica oleracea) phloem tissue proteome

Background: The transport of sugars, hormones, amino acids, proteins, sugar alcohols, and other organic compounds from the sites of synthesis to the sites of use or storage occurs through the conducting cells of the phloem. To better understand these processes a comprehensive understanding of the proteins involved is required. While a considerable amount of data has been obtained from proteomic analyses of phloem sap, this has mainly served to identify the soluble proteins that are translocated through the phloem network.Results: In order to obtain more comprehensive proteomic data from phloem tissue we developed a simple dissection procedure to isolate phloem tissue from Brassica oleracea. The presence of a high density of phloem sieve elements was confirmed using light microscopy and fluorescently labeled sieve element-specific antibodies. To increase the depth of the proteomic analysis for membrane bound and associated proteins, soluble proteins were extracted first and subsequent extractions were carried out using two different detergents (SDS and CHAPSO). Across all three extractions almost four hundred proteins were identified and each extraction method added to the analysis demonstrating the utility of an approach combining several extraction protocols.Conclusions: The phloem was found to be enriched in proteins associated with biotic and abiotic stress responses and structural proteins. Subsequent expression analysis identified a number of genes that appear to be expressed exclusively or at very high levels in phloem tissue, including genes that are known to express specifically in the phloem as well as novel phloem genes.Peer reviewedBiochemistry and Molecular Biolog

Development of a model of focal pneumococcal pneumonia in young rats

BACKGROUND: A recently licensed pneumococcal conjugate vaccine has been shown to be highly effective in the prevention of bacteremia in immunized children but the degree of protection against pneumonia has been difficult to determine. METHODS: We sought to develop a model of Streptococcus pneumoniae pneumonia in Sprague-Dawley rats. We challenged three-week old Sprague-Dawley pups via intrapulmonary injection of S. pneumoniae serotypes 3 and 6B. Outcomes included bacteremia, mortality as well histologic sections of the lungs. RESULTS: Pneumonia was reliably produced in animals receiving either 10 or 100 cfu of type 3 pneumococci, with 30% and 50% mortality respectively. Similarly, with type 6B, the likelihood of pneumonia increased with the inoculum, as did the mortality rate. Prophylactic administration of a preparation of high-titered anticapsular antibody prevented the development of type 3 pneumonia and death. CONCLUSION: We propose that this model may be useful for the evaluation of vaccines for the prevention of pneumococcal pneumonia

A note on "Constraints on deep-seated zonal winds inside Jupiter and Saturn"

Liu et al. 2008 discuss an important consideration for models of zonal winds deep within giant planets. However, the constraints they propose for the depth of the winds are based on their prescriptions for the internal structures of the magnetic field and zonal winds. The same kinematic analysis applied to other plausible configurations would produce no constraint on the depth to which the winds extend.Comment: accepted for publication in Icaru