Analysis and Identification of Requirements for a System to Enhance Situational Awareness at Sea

This paper presents the research results of identifying and analyzing key requirements for the ESABALT system based on pre-defined user profile groups. These requirements have been identified through multiple sources, which include an electronic survey of potential users of the system, interviews with specialists in navigation, law and computer science, analysis of state-of-the-art in maritime safety procedures, and study of past R&D projects in this field. Finally, these requirements are classified into user level, domain level and system level requirements for easy interpretation while designing the system architecture and its function-al specifications. The presented system specification is discussed

Maritime Safety - Stakeholders in Information Exchange Process

This paper presents the methodology and research results on identification of potential users of the ESABALT system, which is targeted towards improving the situational awareness in the Baltic Sea region. We describe the technique of analysing the stakeholders involved in maritime sector processes, especially in maritime transport processes, while also taking into account their different classification criteria. The resulting list of stakeholders is used to identify system users and their classification into user profiles groups. This study will form the basis for the identification of user requirements of the ESABALT system

IMPACT OF NOISE, OTHER AIR POLLUTANTS AND METEOROLOGICAL FACTORS ON MENTAL HEALTH ADMISSIONS IN HOSPITAL

A few environmental components, including air contamination, noise in populated regions, and meteorological-type factors, may have huge effect on human health. These factors might impact the ascent in crisis hospital confirmations because of these variables, since a few examinations lately have demonstrated the connection between different mental sicknesses and these conditions. It is conceivable that the elevated degrees of air contamination are to be faulted for the developing mental health issues among the metropolitan populace in arising countries. It is unprecedented to find enormous scope exact investigations that investigate this case on a public level. To check this suspicion, we fabricated an everyday mental health metric using the amount of mental-health-related look on Baidu, the greatest web crawler in China. Our examination shows that openness to air contamination for a more drawn out timeframe impacts individuals' mental health. Men, people in their center years, and the individuals who are hitched are more vulnerable to the pessimistic impacts of air contamination on mental health, as per heterogeneity examinations.

ESABALT - Improvement of Situational Awareness in the Baltic with the Use of Crowdsourcing

This paper presents the key assumptions and preliminary research on an integrated system called ESABALT, for enhancing maritime safety, which incorporates the latest technological advances in positioning, e-Navigation, Earth observation systems and multi-channel cooperative communications. The most novel part of the ESABALT concept, however, is a focus on user-driven crowdsourcing techniques for information gathering and integration. The system will consist of a situational awareness solution for real-time maritime traffic monitoring via utilizing various positioning technologies; an observation system of the marine environment relevant to transportation and accidents including assessing the sea ice, oil spread, waves, wind etc.; and a methodology for context-aware maritime communication with cooperative, multi-channel capabilities. The paper presents the intelligent, novel, user-driven solution and associated services developed in ESABALT for enhancing the maritime safety in the whole Baltic area

The influence of particle(s) size, shape and distribution on cake filtration mechanics—a short review

The filtration properties in solid–liquid separation mainly depend upon the filter cake properties, for instance, cake resistance. However, particle size distribution, particle shape, and their arrangements significantly impact cake filtration. This paper aims to review the work done so far and collate both fundamental and applied work with regard to the quantification of cake properties. The cake resistance and cake porosity in terms of shape, as well as varying particle size distribution width, are discussed here. This work summarizes the current state of the technology and recommends advancements and improvements for future research

The influence of particle(s) size, shape and distribution on cake filtration mechanics—a short review

The filtration properties in solid–liquid separation mainly depend upon the filter cake properties, for instance, cake resistance. However, particle size distribution, particle shape, and their arrangements significantly impact cake filtration. This paper aims to review the work done so far and collate both fundamental and applied work with regard to the quantification of cake properties. The cake resistance and cake porosity in terms of shape, as well as varying particle size distribution width, are discussed here. This work summarizes the current state of the technology and recommends advancements and improvements for future research

Evaluation of the drug solubility and rush ageing on drug release performance of various model drugs from the modified release polyethylene oxide matrix tablets

Hydrophilic matrix systems are currently some of the most widely used drug delivery systems for controlled-release oral dosage forms. Amongst a variety of polymers, polyethylene oxide (PEO) is considered an important material used in pharmaceutical formulations. As PEO is sensitive to thermal oxidation, it is susceptible to free radical oxidative attack. The aim of this study was to investigate the stability of PEO based formulations containing different model drugs with different water solubility, namely propranolol HCl, theophylline and zonisamide. Both polyox matrices 750 and 303 grade were used as model carriers for the manufacture of tablets stored at 40 °C. The results of the present study suggest that the drug release from the matrix was affected by the length of storage conditions, solubility of drugs and the molecular weight of the polymers. Generally, increased drug release rates were prevalent in soluble drug formulations (propranolol) when stored at the elevated temperature (40 °C). In contrast, it was not observed with semi soluble (theophylline) and poorly soluble (zonisamide) drugs especially when formulated with PEO 303 polymer. This indicates that the main parameters controlling the drug release from fresh polyox matrices are the solubility of the drug in the dissolution medium and the molecular weight of the polymer. DSC traces indicated that that there was a big difference in the enthalpy and melting points of fresh and aged PEO samples containing propranolol, whereas the melting point of the aged polyox samples containing theophylline and zonisamide was unaffected

Priprava i evaluacija mukoadhezivnih filmova glipizida

Glipizide is mainly absorbed in the proximal areas of the gastrointestinal tract. The purpose of this study was formulation and evaluation of mucoadhesive films to prolong the stay of drug in its absorption area. Glipizide was formulated in a mucoadhesive film that could be retained in the stomach for prolonged time intervals. Polymeric films were designed with various compositions of hydroxypropyl cellulose and polyethylene glycol 400 (PEG 400). Properties of the mucoadhesive film such as tensile strength, percentage elongation, swelling index, moisture content, pH and viscosity of polymeric dispersion, film thickness, drug concentration, uniformity and mucoadhesion in a simulated gastric environment were evaluated. In addition, percentage drug retained in stomach mucosa was estimated using a simulated dynamic stomach system as a function of time. Increase in hydroxypropyl cellulose concentration resulted in a higher tensile strength and elongation at break, while increase in concentration of PEG 400 was reflected in a decrease of tensile strength and increase of elongation at break. Glipizide/hydroxypropyl cellulose/PEG 400 (2.5:1:0.5) (GF5) was found to be the optimal composition for a novel mucoadhesive stomach formulation that showed good peelability, relatively high swelling index, moderate tensile strength, and stayed on rat stomach mucosa up to 8 h. In vivo testing of the mucoadhesive films with glipizide demonstrated a potential hypoglycemic effect.Glipizid se pretežno apsorbira u proksimalnom dijelu gastrointestinalnog trakta. Cilj rada je priprava i evaluacija mukoadhezivnih filmova s kojima bi se produljilo zadržavanje lijeka u predjelu apsorpcije. Pripravljeni su mukoadhezivni filmovi glipizida koji se produljeno zadržavaju u želucu. Polimerni filmovi sadržavali su različite količine hidroksipropil celuloze i polietilen glikola 400 (PEG 400). Evaluirana su sljedeća svojstva mukoadhezivnih filmova: čvrstoća, postotak elongacije, indeks bubrenja, sadržaj vlage, pH i viskoznost polimerne disperzije, debljina filma, koncentracija lijeka, jednolikost i mukoadhezivnost u simuliranom želučanom soku. Na dinamičkom modelu želuca određivan je i postotak lijeka koji se zadržava u sluznici želuca u ovisnosti o vremenu. Povećanjem koncentracije hidroksipropil celuloze povećavaju se čvrstoća i elongacija, dok se povećanje koncentracije PEG 400 reflektira na smanjenje čvrstoće i povećanje elongacije kod loma. Omjer glipizid/hidroksipropil celuloza/PEG 400 (2,5:1:0,5) (GF5) bio je optimalan za pripravu mukoadhezivnih formulacija, s dobrom kalavošću, relativno visokim indeksom bubrenja, umjerenom čvrstoćom te zadržavanjem u sluznici želuca štakora do 8 h. U in vivo testiranjima mukoadhesivni filmovi s glipizidom pokazali su potencijalni hipoglikemijski učinak