Mass Flows in Cometary UCHII Regions

High spectral and spatial resolution, mid-infrared fine structure line observations toward two ultracompact HII (UCHII) regions (G29.96 -0.02 and Mon R2) allow us to study the structure and kinematics of cometary UCHII regions. In our earlier study of Mon R2, we showed that highly organized mass motions accounted for most of the velocity structure in that UCHII region. In this work, we show that the kinematics in both Mon R2 and G29.96 are consistent with motion along an approximately paraboloidal shell. We model the velocity structure seen in our mapping data and test the stellar wind bow shock model for such paraboloidal like flows. The observations and the simulation indicate that the ram pressures of the stellar wind and ambient interstellar medium cause the accumulated mass in the bow shock to flow along the surface of the shock. A relaxation code reproduces the mass flow's velocity structure as derived by the analytical solution. It further predicts that the pressure gradient along the flow can accelerate ionized gas to a speed higher than that of the moving star. In the original bow shock model, the star speed relative to the ambient medium was considered to be the exit speed of ionized gas in the shell.Comment: 34 pages, including 14 figures and 1 table, to be published in ApJ, September 200

An Analysis of Private School Closings

We add to the small literature on private school supply by exploring exits of K-12 private schools. We find that the closure of private schools is not an infrequent event, and use national survey data from the National Center for Education Statistics to study closures of private schools. We assume that the probability of an exit is a function of excess supply of private schools over the demand, as well as the school's characteristics such as age, size, and religious affiliation. Our empirical results generally support the implications of the model. Working Paper 07-0

Re-analysis of the radio luminosity function of Galactic HII regions

We have re-analyzed continuum and recombination lines radio data available in the literature in order to derive the luminosity function (LF) of Galactic HII regions. The study is performed by considering the first and fourth Galactic quadrants independently. We estimate the completeness level of the sample in the fourth quadrant at 5 Jy, and the one in the first quadrant at 2 Jy. We show that the two samples (fourth or first quadrant) include, as well as giant and super-giant HII regions, a significant number of sub-giant sources. The LF is obtained, in each Galactic quadrant, with a generalized Schmidt's estimator using an effective volume derived from the observed spatial distribution of the considered HII regions. The re-analysis also takes advantage of recently published ancillary absorption data allowing to solve the distance ambiguity for several objects. A single power-law fit to the LFs retrieves a slope equal to -2.23+/-0.07 (fourth quadrant) and to -1.85+/-0.11 (first quadrant). We also find marginal evidence of a luminosity break at L_knee = 10^23.45 erg s^(-1) Hz^(-1) for the LF in the fourth quadrant. We convert radio luminosities into equivalent H_alpha and Lyman continuum luminosities to facilitate comparisons with extra-galactic studies. We obtain an average total HII regions Lyman continuum luminosity of 0.89 +/- 0.23 * 10^(53) sec^(-1), corresponding to 30% of the total ionizing luminosity of the Galaxy.Comment: accepted for publication in Ap

The cryomechanical design of MUSIC: a novel imaging instrument for millimeter-wave astrophysics at the Caltech Submillimeter Observatory

MUSIC (Multicolor Submillimeter kinetic Inductance Camera) is a new facility instrument for the Caltech Submillimeter Observatory (Mauna Kea, Hawaii) developed as a collaborative effect of Caltech, JPL, the University of Colorado at Boulder and UC Santa Barbara, and is due for initial commissioning in early 2011. MUSIC utilizes a new class of superconducting photon detectors known as microwave kinetic inductance detectors (MKIDs), an emergent technology that offers considerable advantages over current types of detectors for submillimeter and millimeter direct detection. MUSIC will operate a focal plane of 576 spatial pixels, where each pixel is a slot line antenna coupled to multiple detectors through on-chip, lumped-element filters, allowing simultaneously imaging in four bands at 0.86, 1.02, 1.33 and 2.00 mm. The MUSIC instrument is designed for closed-cycle operation, combining a pulse tube cooler with a two-stage Helium-3 adsorption refrigerator, providing a focal plane temperature of 0.25 K with intermediate temperature stages at approximately 50, 4 and 0.4 K for buffering heat loads and heat sinking of optical filters. Detector readout is achieved using semi-rigid coaxial cables from room temperature to the focal plane, with cryogenic HEMT amplifiers operating at 4 K. Several hundred detectors may be multiplexed in frequency space through one signal line and amplifier. This paper discusses the design of the instrument cryogenic hardware, including a number of features unique to the implementation of superconducting detectors. Predicted performance data for the instrument system will also be presented and discussed

What happens for informal caregivers during transition to increased levels of care for the person with dementia? A systematic review protocol

Abstract Background Dementia is a globally prevalent disease that requires ongoing and increasing levels of care, often provided in the first instance by informal caregivers. Supporting transitions in informal caregiving in dementia is a pertinent issue for caregivers, care providers and governments. There is no existing systematic review that seeks to identify and map the body of literature regarding the review question: ‘What happens for informal caregivers during transition to increased levels of care for the person with dementia?’ Methods/design ASSIA, CINAHL+, MEDLINE, PsycINFO, SCIE, Social Service Abstracts and Web of Science will be systematically searched. Specialist dementia research libraries will be contacted. Reviews identified as relevant during the search process, their reference lists, and reference lists of accepted papers will be hand-searched. Qualitative, quantitative and mixed methods studies that seek to represent the experiences of, or examine the impact upon, informal caregivers during transition to increased formal care for the person with dementia will be eligible for inclusion. Synthesis will be segregated into qualitative and quantitative papers. Findings will be summarised, and the review will be prepared for publication. Discussion The review will seek to identify potentially vulnerable groups in need of support and as such, inform the practice of those offering support. It will also inform future research by highlighting areas in which current literature is insubstantial. Systematic review registration PROSPERO CRD4201706724

Neuroprotection in a Novel Mouse Model of Multiple Sclerosis

The authors acknowledge the support of the Barts and the London Charity, the Multiple Sclerosis Society of Great Britain and Northern Ireland, the National Multiple Sclerosis Society, USA, notably the National Centre for the Replacement, Refinement & Reduction of Animals in Research, and the Wellcome Trust (grant no. 092539 to ZA). The siRNA was provided by Quark Pharmaceuticals. The funders and Quark Pharmaceuticals had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

Are Debris Disks and Massive Planets Correlated?

Using data from the Spitzer Space Telescope Legacy Science Program ``Formation and Evolution of Planetary Systems'' (FEPS), we have searched for debris disks around 9 FGK stars (2-10 Gyr), known from radial velocity (RV) studies to have one or more massive planets. Only one of the sources, HD 38529, has excess emission above the stellar photosphere; at 70 micron the signal-to-noise ratio in the excess is 4.7 while at wavelengths < 30 micron there is no evidence of excess. The remaining sources show no excesses at any Spitzer wavelengths. Applying survival tests to the FEPS sample and the results for the FGK survey published in Bryden et al. (2006), we do not find a significant correlation between the frequency and properties of debris disks and the presence of close-in planets. We discuss possible reasons for the lack of a correlation.Comment: 24 pages, 3 figures. Accepted to Astrophysical Journa

Optics for MUSIC: a new (sub)millimeter camera for the Caltech Submillimeter Observatory

We will present the design and implementation, along with calculations and some measurements of the performance, of the room-temperature and cryogenic optics for MUSIC, a new (sub)millimeter camera we are developing for the Caltech Submm Observatory (CSO). The design consists of two focusing elements in addition to the CSO primary and secondary mirrors: a warm off-axis elliptical mirror and a cryogenic (4K) lens. These optics will provide a 14 arcmin field of view that is diffraction limited in all four of the MUSIC observing bands (2.00, 1.33, 1.02, and 0.86 mm). A cold (4K) Lyot stop will be used to define the primary mirror illumination, which will be maximized while keeping spillover at the sub 1% level. The MUSIC focal plane will be populated with broadband phased antenna arrays that efficiently couple to factor of (see manuscript) 3 in bandwidth, and each pixel on the focal plane will be read out via a set of four lumped element filters that define the MUSIC observing bands (i.e., each pixel on the focal plane simultaneously observes in all four bands). Finally, a series of dielectric and metal-mesh low pass filters have been implemented to reduce the optical power load on the MUSIC cryogenic stages to a quasi-negligible level while maintaining good transmission in-band